{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T15:14:21Z","timestamp":1787670861228,"version":"build-2736575974"},"reference-count":38,"publisher":"Georg Thieme Verlag KG","issue":"06","funder":[{"name":"Academic Pediatric Association"},{"name":"National Center for Advancing Translational Sciences, National Institutes of Health","award":["UL1 TR001860"],"award-info":[{"award-number":["UL1 TR001860"]}]},{"name":"National Institutes of Health Building Interdisciplinary Research Careers in Women's Health Program","award":["K12HD051958"],"award-info":[{"award-number":["K12HD051958"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:p>\n            Objective\u2003There is a paucity of evidence to guide the clinical care of late preterm and term neonates born to women with perinatal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The objective of this case series is to describe early neonatal outcomes and inpatient management in U.S. hospitals.<\/jats:p><jats:p>\n            Study Design\u2003We solicited cases of mother\u2013infant dyads affected by novel coronavirus disease 2019 (COVID-19) from the Better Outcomes through Research for Newborns (BORN) Network members. Using a structured case template, participating sites contributed deidentified, retrospective birth hospitalization data for neonates \u226535 weeks of gestation at birth with mothers who tested positive for SARS-CoV-2 before delivery. We describe demographic and clinical characteristics, clinical management, and neonatal outcomes.<\/jats:p><jats:p>\n            Results\u2003Sixteen U.S. hospitals contributed 70 cases. Birth hospitalizations were uncomplicated for 66 (94%) neonates in which 4 (6%) required admission to a neonatal intensive care unit. None required evaluation or treatment for infection, and all who were tested for SARS-CoV-2 were negative (n\u2009=\u200957). Half of the dyads were colocated (n\u2009=\u200934) and 40% directly breastfed (n\u2009=\u200928). Outpatient follow-up data were available for 13 neonates, all of whom remained asymptomatic.<\/jats:p><jats:p>\n            Conclusion\u2003In this multisite case series of 70 neonates born to women with SARS-CoV-2 infection, clinical outcomes were overall good, and there were no documented neonatal SARS-CoV-2 infections. Clinical management was largely inconsistent with contemporaneous U.S. COVID-19 guidelines for nursery care, suggesting concerns about the acceptability and feasibility of those recommendations. Longitudinal studies are urgently needed to assess the benefits and harms of current practices to inform evidence-based clinical care and aid shared decision-making.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0041-1726036","type":"journal-article","created":{"date-parts":[[2021,3,16]],"date-time":"2021-03-16T07:33:55Z","timestamp":1615880035000},"page":"622-631","source":"Crossref","is-referenced-by-count":15,"title":["Management and Early Outcomes of Neonates Born to Women with SARS-CoV-2 in 16 U.S. Hospitals"],"prefix":"10.1055","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6424-2189","authenticated-orcid":false,"given":"Jayme L.","family":"Congdon","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of California San Francisco, San Francisco, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura R.","family":"Kair","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of California, Davis, Sacramento, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie J.","family":"Flaherman","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of California San Francisco, San Francisco, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly E.","family":"Wood","sequence":"additional","affiliation":[{"name":"Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Ann","family":"LoFrumento","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Columbia University, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eberechi","family":"Nwaobasi-Iwuh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Morristown Medical Center, Atlantic Health System, Morristown, New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carrie A.","family":"Phillipi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Oregon Health and Science University, Portland, Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the Better Outcomes through Research for Newborns (BORN) Network","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,3,15]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/S0140-6736(20)30360-3","article-title":"Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records","volume":"395","author":"H 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