{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T01:49:06Z","timestamp":1788400146548,"version":"build-2803163510"},"reference-count":14,"publisher":"Scientific Scholar","license":[{"start":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T00:00:00Z","timestamp":1618272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["ruralneuropractice.com"],"crossmark-restriction":true},"short-container-title":["JNRP"],"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p>Even for seasoned neurosurgeons who have mastered the microvascular decompression (MVD) techniques, trigeminal neuralgia (TGN) secondary to vertebrobasilar dolichoectatic vessels remains a challenge. Often, patient is either medically infirm or unwilling for invasive surgical interventions. Alternative treatment options including Gamma Knife radiosurgery (GKRS) are considered in such a situation with variable success. This study aimed to evaluate the role of GKRS in patients with trigeminal neuralgia with dolichoectatic vessels and severe cross compression. We prospectively managed three male patients of intractable TGN secondary to dolichoectatic vascular compression with single-session GKRS. The cisternal component of the trigeminal nerve was targeted with 90 Gy radiation at 100% isodose with a single 4-mm collimator. The patients were regularly evaluated on clinical parameters for pain relief (Barrow Neurological Institute (BNI) score), sensory complaints, and outcome. All patients had satisfactory pain control (BNI I\u2013IIIa) at 3 months of interval only to get recurrent pain (BNI IV\u2013V) after 6 months. The treatment was eventually considered a failure after 6-month duration and one patient needed MVD for pain control. Post-GKRS pain control remains inferior in patients with dolichoectasia compared with typical TGN. GKRS should be offered only as a salvage or rescue procedure and should not be used as an alternative treatment of MVD in patient population with dolichoectatic vessels.<\/jats:p>","DOI":"10.1055\/s-0041-1726150","type":"journal-article","created":{"date-parts":[[2021,4,14]],"date-time":"2021-04-14T01:19:29Z","timestamp":1618363169000},"page":"455-460","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Radiosurgery for Trigeminal Neuralgia Secondary to Dolichoectatic Vessels: Case Series and Review of Literature"],"prefix":"10.25259","volume":"12","author":[{"given":"Manjul","family":"Tripathi","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India"},{"name":"National Institute of Health Research (NIHR) Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Mohindra","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renu","family":"Madan","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chirag K.","family":"Ahuja","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aman","family":"Batish","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rupinder","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sushant","family":"Dutta","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ninad R.","family":"Patil","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasundhara S.","family":"Rangan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Nizam Institute of Medical Sciences, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonikpreet","family":"Aulakh","sequence":"additional","affiliation":[{"name":"Department of Translational Neuro-Oncology, West Virginia Cancer Institute, Morgantown, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2021,4,13]]},"reference":[{"issue":"2","key":"10.1055\/s-0041-1726150\/ref-1","doi-asserted-by":"crossref","first-page":"414","DOI":"10.4103\/0028-3886.258020","article-title":"Trigeminal neuralgia: an orphan with many fathers","volume":"67","author":"Tripathi","year":"2019","journal-title":"Neurol India"},{"issue":"5","key":"10.1055\/s-0041-1726150\/ref-2","first-page":"1","article-title":"Letter to the editor. Microsurgical rhizotomy as treatment for trigeminal neuralgia in patients with multiple sclerosis: turnpike or dirt road?","volume":"130","author":"Deora","year":"2018","journal-title":"J Neurosurg"},{"issue":"3","key":"10.1055\/s-0041-1726150\/ref-3","doi-asserted-by":"crossref","first-page":"733","DOI":"10.3171\/2017.9.JNS17545","article-title":"Stereotactic radiosurgery for trigeminal neuralgia: a systematic review","volume":"130","author":"Tuleasca","year":"2018","journal-title":"J Neurosurg"},{"issue":"3","key":"10.1055\/s-0041-1726150\/ref-4","first-page":"1","article-title":"Letter to the Editor. Cafeteria approach to management of trigeminal neuralgia: stereotactic radiosurgery as a preferred option","volume":"130","author":"Tripathi","year":"2018","journal-title":"J Neurosurg"},{"issue":"1","key":"10.1055\/s-0041-1726150\/ref-5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/jns.1994.81.1.0001","article-title":"Microvascular decompression for trigeminal neuralgia caused by vertebrobasilar compression","volume":"81","author":"Linskey","year":"1994","journal-title":"J Neurosurg"},{"issue":"1","key":"10.1055\/s-0041-1726150\/ref-6","doi-asserted-by":"crossref","first-page":"73","DOI":"10.3171\/2011.8.JNS11920","article-title":"Outcomes of Gamma Knife surgery for trigeminal neuralgia secondary to vertebrobasilar ectasia","volume":"116","author":"Park","year":"2012","journal-title":"J Neurosurg"},{"issue":"8","key":"10.1055\/s-0041-1726150\/ref-7","doi-asserted-by":"crossref","first-page":"742","DOI":"10.2176\/nmc.27.742","article-title":"[Trigeminal neuralgia due to compression of the trigeminal root by a basilar artery trunk. Report of 45 cases] (in Japanese)","volume":"27","author":"Miyazaki","year":"1987","journal-title":"Neurol Med Chir (Tokyo)"},{"issue":"1","key":"10.1055\/s-0041-1726150\/ref-8","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1590\/S0004-282X2006000100027","article-title":"Vertebrobasilar dolichoectasia as a cause of trigeminal neuralgia: the role of microvascular decompression. Case report","volume":"64","author":"Kraemer","year":"2006","journal-title":"Arq Neuropsiquiatr"},{"issue":"4","key":"10.1055\/s-0041-1726150\/ref-9","first-page":"341","article-title":"Microvascular decompression for trigeminal neuralgia: the importance of a noncompressive technique\u2013Kaplan-Meier analysis in a consecutive series of 330 patients","volume":"63","author":"Sindou","year":"2008","journal-title":"Neurosurgery"},{"issue":"3","key":"10.1055\/s-0041-1726150\/ref-10","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1159\/000362172","article-title":"Trigeminal neuralgia related to megadolichobasilar artery compression: a prospective series of twenty-nine patients treated with gamma knife surgery, with more than one year of follow-up","volume":"92","author":"Tuleasca","year":"2014","journal-title":"Stereotact Funct Neurosurg"},{"issue":"1","key":"10.1055\/s-0041-1726150\/ref-11","first-page":"61","article-title":"High-resolution computed tomography of the basilar artery: 2. Vertebrobasilar dolichoectasia: clinical-pathologic correlation and review","volume":"7","author":"Smoker","year":"1986","journal-title":"AJNR Am J Neuroradiol"},{"issue":"1","key":"10.1055\/s-0041-1726150\/ref-12","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1212\/01.wnl.0000286947.89193.f3","article-title":"Natural history of vertebrobasilar dolichoectasia","volume":"70","author":"Passero","year":"2008","journal-title":"Neurology"},{"issue":"6","key":"10.1055\/s-0041-1726150\/ref-13","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.3171\/2009.6.JNS09469","article-title":"Trigeminal neuralgia in the presence of ectatic basilar artery and basilar invagination: treatment by foramen magnum decompression","volume":"111","author":"Goel","year":"2009","journal-title":"J Neurosurg"},{"key":"10.1055\/s-0041-1726150\/ref-14","doi-asserted-by":"crossref","first-page":"455","DOI":"10.25259\/SNI_729_2020","article-title":"Please spare my teeth! Dental procedures and trigeminal neuralgia.","volume":"11","author":"Tripathi","year":"2020","journal-title":"Surg Neurol Int."}],"container-title":["Journal of Neurosciences in Rural Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ruralneuropractice.com\/radiosurgery-for-trigeminal-neuralgia-secondary-to-dolichoectatic-vessels-case-series-and-review-of-literature\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ruralneuropractice.com\/radiosurgery-for-trigeminal-neuralgia-secondary-to-dolichoectatic-vessels-case-series-and-review-of-literature\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T04:40:12Z","timestamp":1691210412000},"score":1,"resource":{"primary":{"URL":"https:\/\/ruralneuropractice.com\/radiosurgery-for-trigeminal-neuralgia-secondary-to-dolichoectatic-vessels-case-series-and-review-of-literature\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,13]]},"references-count":14,"alternative-id":["10.1055\/s-0041-1726150"],"URL":"https:\/\/doi.org\/10.1055\/s-0041-1726150","relation":{},"ISSN":["0976-3147"],"issn-type":[{"value":"0976-3147","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,13]]},"article-number":"455"}}