{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:43:44Z","timestamp":1760647424531,"version":"3.37.3"},"reference-count":21,"publisher":"Georg Thieme Verlag KG","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:p>\n            Objective\u2003This study was aimed to determine mydriatic regimen(s) used in neonatal units in Aotearoa, New Zealand (NZ), and Australia and to estimate the frequency of adverse drug events following mydriatic administration in preterm neonates.<\/jats:p><jats:p>\n            Study Design\u2003A cross-sectional survey was sent to neonatal nursing staff listed in the Australian and New Zealand Neonatal Network contact list. Participants were asked to state what mydriatic regimen they use, and to estimate the frequency of adverse drug events when eye drops were administered for retinopathy of prematurity eye examinations (ROPEE).<\/jats:p><jats:p>\n            Results\u2003Thirteen different mydriatic regimens were identified; phenylephrine 2.5% and cyclopentolate 0.5% (1 standard drop of each) was the most commonly used regimen. Two of the regimens exceeded adult doses and five regimens included a mydriatic that is equivalent to an adult dose. Following mydriatic instillation, the three most common adverse effects were apnea, tachycardia, and periorbital pallor.<\/jats:p><jats:p>\n            Conclusion\u2003Low-concentration single-microdrop regimens are currently in use and resulting in successful ROPEE, yet doses exceeding adult doses are in use throughout Aotearoa, NZ, and Australian units. We know from this dataset that neonates are experiencing unwanted and potentially preventable, adverse effects associated with mydriatics, and every effort should be made to minimize this risk.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0041-1726316","type":"journal-article","created":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T22:56:42Z","timestamp":1617145002000},"page":"1779-1785","source":"Crossref","is-referenced-by-count":4,"title":["A Survey of Neonatal Nurses on Mydriatic Regimens Used in Neonatal Retinopathy of Prematurity Eye Examinations"],"prefix":"10.1055","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9068-4391","authenticated-orcid":false,"given":"Lisa","family":"Kremer","sequence":"additional","affiliation":[{"name":"School of Pharmacy, University of Otago, Dunedin, Aotearoa, New Zealand"},{"name":"Department of Women's and Children's Health, Dunedin School of Medicine, University of Otago, Dunedin, Aotearoa, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Reith","sequence":"additional","affiliation":[{"name":"Deans Department, Dunedin School of Medicine, University of Otago, Dunedin, Aotearoa, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie J.","family":"Medlicott","sequence":"additional","affiliation":[{"name":"School of Pharmacy, University of Otago, Dunedin, Aotearoa, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary J.","family":"Sime","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Dunedin Hospital, Dunedin, Aotearoa, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liza","family":"Edmonds","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health, Dunedin School of Medicine, University of Otago, Dunedin, Aotearoa, New Zealand"},{"name":"Neonatal Intensive Care Unit, Dunedin Hospital, Dunedin, Aotearoa, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Broadbent","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health, Dunedin School of Medicine, University of Otago, Dunedin, Aotearoa, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,3,30]]},"reference":[{"issue":"12","key":"ref2","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1001\/archopht.121.12.1684","article-title":"Revised indications for the treatment of retinopathy of prematurity: results of the early treatment for retinopathy of prematurity randomized trial","volume":"121","author":"Early Treatment For Retinopathy Of Prematurity Cooperative Group","year":"2003","journal-title":"Arch Ophthalmol"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1001\/archopht.1988.01060130517027","article-title":"Multicenter trial of cryotherapy for retinopathy of prematurity. 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