{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T05:24:13Z","timestamp":1780637053839,"version":"3.54.1"},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:p>Objective\u2003Umbilical venous catheters (UVC) are widely used in neonatal intensive care (NICU). Noncentral catheter position is known to be associated with multiple adverse complications; however, risk factors for catheter malposition are unclear. This work aimed to identify clinical risk factors and complications associated with UVC malposition in neonates admitted in an NICU.<\/jats:p><jats:p>Study Design\u2003A retrospective chart review was performed of inborn babies admitted to BC Women's Hospital NICU with UVC inserted in their first 7 days between July 2016 and June 2018. Infant and maternal demographic, radiograph, UVC-related data, and complications were reviewed.<\/jats:p><jats:p>Results\u2003A total of 257 infants had UVC placed; 158 (61%) and 99 (39%) were in central and noncentral positions after initial placement, respectively. Of initially central-placed UVCs, a further 35 (22%) were pulled back or migrated to malposition on follow-up X-ray. Multivariable logistic regression analysis revealed the use of larger UV (5 Fr) catheter (odds ratio [OR]: 2.5, 95% confidence interval [CI]: 1.1\u20135.6, p\u2009=\u20090.026) and escalation of respiratory support mode (OR: 1.7, 95% CI: 1.0\u20132.8, p\u2009=\u20090.049) as significant predictors of catheter malposition.<\/jats:p><jats:p>Conclusion\u2003Noncentral UVC position as well as migration were common after initial placement in this cohort. The use of larger size UV catheters and increasingly invasive respiratory support were risk factors associated with higher incidence of UVC malposition. Ongoing surveillance of UVC position is thus recommended.<\/jats:p><jats:p>Key Points<\/jats:p>","DOI":"10.1055\/s-0041-1726385","type":"journal-article","created":{"date-parts":[[2021,4,14]],"date-time":"2021-04-14T23:15:14Z","timestamp":1618442114000},"page":"1805-1811","source":"Crossref","is-referenced-by-count":8,"title":["Factors Associated with Umbilical Venous Catheter Malposition in Newborns: A Tertiary Center Experience"],"prefix":"10.1055","volume":"39","author":[{"given":"Sasivimon","family":"Soonsawad","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, BC Women's and Children's Hospital and the University of British Columbia, Canada"},{"name":"Ramathibodi Medical School, Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samut Prakan, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily A.","family":"Kieran","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, BC Women's and Children's Hospital and the University of British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph Y.","family":"Ting","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, BC Women's and Children's Hospital and the University of British Columbia, Canada"},{"name":"BC Children's Hospital Research Institute, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"AlonsoPrieto","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, BC Women's and Children's Hospital and the University of British Columbia, Canada"},{"name":"BC Children's Hospital Research Institute, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia K.","family":"Panczuk","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, BC Women's and Children's Hospital and the University of British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,4,14]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"e1742","DOI":"10.1542\/peds.2013-1373","article-title":"Standardizing umbilical catheter usage in preterm infants","volume":"133","author":"S Shahid","year":"2014","journal-title":"Pediatrics"},{"issue":"04","key":"ref2","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1460-9592.2005.01433.x","article-title":"Umbilical vein catheterization under electrocardiogram guidance","volume":"15","author":"B CH Tsui","year":"2005","journal-title":"Paediatr 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