{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T05:10:56Z","timestamp":1691212256355},"reference-count":28,"publisher":"Scientific Scholar","license":[{"start":{"date-parts":[[2021,5,10]],"date-time":"2021-05-10T00:00:00Z","timestamp":1620604800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["ruralneuropractice.com"],"crossmark-restriction":true},"short-container-title":["JNRP"],"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p>\n<jats:bold>Background<\/jats:bold>\u2003The precise timings of evoked potentials in evaluating the functional outcome of stroke have remained indistinct. Few studies in the Indian context have studied the outcome of early prognosis of stroke utilizing evoked potentials.<\/jats:p>\n<jats:p>\n<jats:bold>Objective<\/jats:bold>\u2003The aim of this study was to determine somatosensory evoked potentials (SSEPs) and brain stem auditory evoked potentials (BAEPs), their timing and abnormalities in acute ischemic stroke involving the middle cerebral artery (MCA) territory and to correlate SSEP and BAEP with the functional outcome (National Institutes of Health Stroke Scale (NIHSS), modified Rankin scale (mRS) and Barthel\u2019s index) at 3 months.<\/jats:p>\n<jats:p>\n<jats:bold>Methods<\/jats:bold>\u2003MCA territory involved acute ischemic stroke patients (<jats:italic>n<\/jats:italic> = 30) presenting consecutively to the hospital within 3 days of symptoms onset were included. Details about clinical symptoms, neurological examination, treatment, NIHSS score, mRS scores were collected at the time of admission. All patients underwent imaging of the brain and were subjected to SSEP and BAEP on two occasions, first at 1 to 3 days and second at 4 to 7 days from the onset of stroke. At 3 months of follow-up, NIHSS, mRS, and Barthel\u2019s index were recorded.<\/jats:p>\n<jats:p>\n<jats:bold>Results<\/jats:bold>\u2003P37 and N20 amplitude had a strong negative correlation (at 1\u20133 and 4\u20137 days) with NIHSS at admission, NIHSS at 3 months, mRS at admission, and mRS at 3 months and a significant positive correlation with Barthel\u2019s index (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). BAEP wave V had a negative correlation (at 1\u20133 and 4\u20137 days) with NIHSS at admission, NIHSS at 3 months, mRS at admission, and mRS at 3 months and a positive correlation with Barthel\u2019s index (<jats:italic>p<\/jats:italic> &lt; 0.0001).<\/jats:p>\n<jats:p>\n<jats:bold>Conclusion<\/jats:bold>\u2003SSEP abnormalities recorded on days 4 to 7 from onset of stroke are more significant than those recorded within 1 to 3 days of onset of stroke; hence, the timing of 4 to 7 days after stroke onset can be considered as better for predicting functional outcome.<\/jats:p>","DOI":"10.1055\/s-0041-1727558","type":"journal-article","created":{"date-parts":[[2021,5,31]],"date-time":"2021-05-31T09:08:07Z","timestamp":1622452087000},"page":"478-482","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Study of Short Latency Somatosensory and Brain Stem Auditory Evoked Potentials Patients with Acute Ischemic Stroke Involving Middle Cerebral Artery Territory"],"prefix":"10.25259","volume":"12","author":[{"given":"Abhishek","family":"Miryala","sequence":"first","affiliation":[{"name":"Department of Neurology, MS Ramaiah Medical College & Hospital, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahendra","family":"Javali","sequence":"additional","affiliation":[{"name":"Department of Neurology, MS Ramaiah Medical College & Hospital, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anish","family":"Mehta","sequence":"additional","affiliation":[{"name":"Department of Neurology, MS Ramaiah Medical College & Hospital, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Pradeep","sequence":"additional","affiliation":[{"name":"Department of Neurology, MS Ramaiah Medical College & Hospital, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Purushottam","family":"Acharya","sequence":"additional","affiliation":[{"name":"Department of Neurology, MS Ramaiah Medical College & Hospital, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rangasetty","family":"Srinivasa","sequence":"additional","affiliation":[{"name":"Department of Neurology, MS Ramaiah Medical College & Hospital, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2021,5,10]]},"reference":[{"issue":"1","key":"10.1055\/s-0041-1727558\/ref-1","first-page":"42","article-title":"Somatosensory evoked potentials in predicting motor deficit after ischemic or hemorrhagic stroke","volume":"41","author":"Calugaru","year":"2015","journal-title":"Curr Health Sci J"},{"issue":"1","key":"10.1055\/s-0041-1727558\/ref-2","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s12028-007-9025-z","article-title":"Evoked potentials in acute ischemic stroke within the first 24 h: possible predictor of a malignant course","volume":"9","author":"Burghaus","year":"2008","journal-title":"Neurocrit Care"},{"issue":"6","key":"10.1055\/s-0041-1727558\/ref-3","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1007\/s13244-012-0185-9","article-title":"Comparison of CT and MR imaging in ischemic stroke","volume":"3","author":"Vymazal","year":"2012","journal-title":"Insights Imaging"},{"issue":"1","key":"10.1055\/s-0041-1727558\/ref-4","doi-asserted-by":"crossref","first-page":"69","DOI":"10.4103\/1673-5374.224375","article-title":"Predictors of short-term outcome in patients with acute middle cerebral artery occlusion: unsuitability of fluid-attenuated inversion recovery vascular hyperintensity scores","volume":"13","author":"Li","year":"2018","journal-title":"Neural Regen Res"},{"key":"10.1055\/s-0041-1727558\/ref-5","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3389\/fneur.2016.00245","article-title":"A critical review of Alberta Stroke Program Early CT Score for evaluation of acute stroke imaging","volume":"7","author":"Schr\u00f6der","year":"2017","journal-title":"Front Neurol"},{"key":"10.1055\/s-0041-1727558\/ref-6","volume":"227","author":"Maddison","year":"2011","unstructured":"Demyelinating disease. 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