{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T02:03:55Z","timestamp":1773799435635,"version":"3.50.1"},"reference-count":11,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Homeopathy"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Acne is a common disorder of the pilosebaceous follicle. The face, back and chest are usually involved. It leads to significant diminution in quality of life. Numerous treatments are documented in therapeutic guidelines. Naturopathic approaches have been proposed in some, but the role of homeopathy is not examined.<\/jats:p><jats:p>\n          Methods\u2003In this study, 83 patients treated for acne with individualised homeopathic medicine alone were reviewed. Most had received conventional acne treatment, with limited success prior to presentation for homeopathy. Each patient was prescribed a single homeopathic medicine and followed up at 6- to 8-week intervals. The individualisation process resulted in 17 different medicines being used in this group. Photographic documentation was obtained per patient, with informed consent. Patients were classified as mild (comedonal acne with no papules or pustules), moderate (inflammatory and non-inflammatory lesions) and severe (predominantly inflammatory lesions: pustules, cysts, nodules). Results of treatment were recorded as remission (decrease in new lesion number, duration and intensity), failure to respond, and lost to follow-up (LTF).<\/jats:p><jats:p>\n          Results\u2003The average age of patients was 21.5 years (range 11\u201345 years). The F:M ratio was 55 (66.3%):28 (33.7%). Average pre-treatment duration was 5.5 years (0.25\u201322 years). Seven (8.4%) patients had mild acne, 37 (44.6%) moderate, and 39 (47%) severe acne. There were 13 (15.7%) LTFs, two (2.4%) failed to respond, and 68 (81.9%) went into remission. Average time to remission was 1.9 months (range 1.5\u20136 months), with no relapses or side-effects. The most commonly prescribed medicines were Lycopodium (38.6%), Palladium (15.7%) and Platinum (12.1%).<\/jats:p><jats:p>\n          Conclusion\u2003Individualised homeopathy may be useful for acne therapy. The most useful medicines appeared to be Lycopodium, Palladium and Platinum, though 17 different medicines were used in this study, underscoring the value of individualisation of therapy, a key characteristic of homeopathy.<\/jats:p>","DOI":"10.1055\/s-0041-1728666","type":"journal-article","created":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T22:56:57Z","timestamp":1625007417000},"page":"271-276","source":"Crossref","is-referenced-by-count":7,"title":["Individualised Homeopathic Treatment of Acne\u2014An Analysis of 83 Patients"],"prefix":"10.1055","volume":"110","author":[{"given":"Lawrence Chukwudi","family":"Nwabudike","sequence":"additional","affiliation":[{"name":"Department of Dermatovenereology, N. Paulescu National Institute of Diabetes, Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,6,29]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1111\/jdv.14475","article-title":"Acne prevalence and associations with lifestyle: a cross-sectional online survey of adolescents\/young adults in 7 European countries","volume":"32","author":"P Wolkenstein","year":"2018","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1111\/bjd.12149","article-title":"Epidemiology of acne vulgaris","volume":"168","author":"K Bhate","year":"2013","journal-title":"Br J Dermatol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.jaad.2015.12.037","article-title":"Guidelines of care for the management of acne vulgaris","volume":"74","author":"A L Zaenglein","year":"2016","journal-title":"J Am Acad Dermatol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1001\/jamadermatol.2020.0465","article-title":"Efficacy and safety of topical clascoterone cream, 1%, for treatment in patients with facial acne: Two phase 3 randomized clinical trials","volume":"156","author":"A Hebert","year":"2020","journal-title":"JAMA Dermatol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"743","DOI":"10.2105\/AJPH.2015.303025","article-title":"Homeopathy use by US adults: results of a national survey","volume":"106","author":"M L Dossett","year":"2016","journal-title":"Am J Public Health"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1001\/archinte.162.10.1176","article-title":"Physicians want education about complementary and alternative medicine to enhance communication with their patients","volume":"162","author":"L S Winslow","year":"2002","journal-title":"Arch Intern Med"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1001\/jamadermatol.2014.2274","article-title":"Comparative prevalence of complementary and alternative medicine use among outpatients in dermatology and primary care clinics","volume":"150","author":"R K Sivamani","year":"2014","journal-title":"JAMA Dermatol"},{"key":"ref8","first-page":"27","article-title":"An observation on successful treatment of acne scar with homeopathic medicine","volume":"6","author":"S Shraddhamayananda","year":"2015","journal-title":"Int J Biopharmaceutics"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1159\/000486309","article-title":"Case reports of acne and homeopathy","volume":"25","author":"L C Nwabudike","year":"2018","journal-title":"Complement Med Res"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.homp.2013.12.002","article-title":"Observational study of Arctium lappa in the treatment of acne vulgaris","volume":"103","author":"A Miglani","year":"2014","journal-title":"Homeopathy"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.ctim.2015.12.019","article-title":"Homeopathic clinical case reports: Development of a supplement (HOM-CASE) to the CARE clinical case reporting guideline","volume":"25","author":"R A van Haselen","year":"2016","journal-title":"Complement Ther Med"}],"container-title":["Homeopathy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0041-1728666.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,8]],"date-time":"2021-11-08T23:38:24Z","timestamp":1636414704000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0041-1728666"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,29]]},"references-count":11,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2021,11,8]]},"published-print":{"date-parts":[[2021,11]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0041-1728666","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1475-4916","1476-4245"],"issn-type":[{"value":"1475-4916","type":"print"},{"value":"1476-4245","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,29]]}}}