{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:08:47Z","timestamp":1791216527842,"version":"4.1.0"},"reference-count":23,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg A Cent Eur Neurosurg"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Large solid hemangioblastoma in the posterior fossa has an abundant blood supply as an arteriovenous malformation. The presence of adjacent vital neurovascular structures makes them vulnerable and difficult to operate. Complete surgical resection is always a challenge to the neurosurgeon.<\/jats:p><jats:p>\n          Material and Method\u2003We share the surgical difficulties and outcome in this case series of large solid hemangioblastomas without preoperative embolization as an adjunct. This study included five patients (three men and two women, with a mean age of 42.2 years). Preoperative embolization was attempted in one patient but was unsuccessful. All the patients have headache (100%) and ataxia (100%) as an initial symptom. A ventriculoperitoneal shunt was inserted in one case before definite surgery due to obstructive hydrocephalus. The surgical outcome was measured using the Karnofsky Performance Status (KPS) score.<\/jats:p><jats:p>\n          Result\u2003The tumor was excised completely in all the cases. No intra- and postoperative morbidity occurred in four patients; one patient developed transient lower cranial nerve palsy. Mean blood loss was 235\u2009mL, and no intraoperative blood transfusion was needed in any case. The mean follow-up period was 14.2 months. The mean KPS score at last follow-up was 80.One patient had a KPS score of 60.<\/jats:p><jats:p>\n          Conclusion\u2003Our treatment strategy is of circumferential dissection followed by en bloc excision, which is the optimal treatment of large solid hemangioblastoma. The use of adjuncts as color duplex sonography and indocyanine green video angiography may help complete tumor excision with a lesser risk of complication. Preoperative embolization may not be needed to resect large solid posterior fossa hemangioblastoma, including those at the cerebellopontine angle location.<\/jats:p>","DOI":"10.1055\/s-0041-1728766","type":"journal-article","created":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T22:51:17Z","timestamp":1629931877000},"page":"224-230","source":"Crossref","is-referenced-by-count":1,"title":["Surgical Outcome of Large Solid Posterior Fossa Hemangioblastoma without Preoperative Embolization"],"prefix":"10.1055","volume":"83","author":[{"given":"Prashant Raj","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, AIIMS, Raipur, Chhattisgarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raghvendra Kumar","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, AIIMS, Raipur, Chhattisgarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jitender","family":"Chaturvedi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, AIIMS, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitish","family":"Nayak","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, AIIMS, Raipur, Chhattisgarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil Kumar","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, AIIMS, Raipur, Chhattisgarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,8,25]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"e1049","DOI":"10.1016\/j.wneu.2017.11.173","article-title":"Hemangioblastomas of the posterior cranial fossa in adults: demographics, clinical, morphologic, pathologic, surgical features, and outcomes. 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