{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:44:41Z","timestamp":1761129881730,"version":"3.37.3"},"reference-count":52,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"05","license":[{"start":{"date-parts":[[2021,6,28]],"date-time":"2021-06-28T00:00:00Z","timestamp":1624838400000},"content-version":"vor","delay-in-days":58,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003Coronavirus disease 2019 (COVID-19) is a disease caused by a newly discovered coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which usually leads to non-specific respiratory symptoms. Although pregnant women are considered at risk for respiratory infections by other viruses, such as SARS and Middle East respiratory syndrome (MERS), little is known about their vulnerability to SARS-CoV-2. Therefore, this study aims to identify and present the main studies on the topic, including the postpartum period.<\/jats:p><jats:p>\n          Methods\u2003In this narrative review, articles were searched in various databases, organizations, and health entities using keywords compatible with medical subject headings (MeSH), such as: COVID-19, pregnancy, vertical transmission, coronavirus 2019, and SARS-CoV-2.<\/jats:p><jats:p>\n          Results\u2003The review of the scientific literature on the subject revealed that pregnant women with COVID-19 did not present clinical manifestations significantly different from those of non-pregnant women; however, there are contraindicated therapies. Regarding fetuses, studies were identified that reported that infection by SARS-CoV-2 in pregnant women can cause fetal distress, breathing difficulties and premature birth, but there is no substantial evidence of vertical transmission.<\/jats:p><jats:p>\n          Conclusion\u2003Due to the lack of adequate information and the limitations of the analyzed studies, it is necessary to provide detailed clinical data on pregnant women infected with SARS-CoV-2 and on the maternal-fetal repercussions caused by this infection. Thus, this review may contribute to expand the knowledge of professionals working in the area as well as to guide more advanced studies on the risk related to pregnant women and their newborns. Meanwhile, monitoring of confirmed or suspected pregnant women with COVID-19 is essential, including in the postpartum period.<\/jats:p>","DOI":"10.1055\/s-0041-1729145","type":"journal-article","created":{"date-parts":[[2021,6,28]],"date-time":"2021-06-28T22:33:51Z","timestamp":1624919631000},"page":"384-394","source":"Crossref","is-referenced-by-count":4,"title":["Clinical Features and Maternal-fetal Results of Pregnant Women in COVID-19 Times"],"prefix":"10.61622","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9158-3218","authenticated-orcid":false,"given":"Ana Paula Nogueira","family":"Godoi","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Jo\u00e3o del-Rei, Divin\u00f3polis, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2839-2443","authenticated-orcid":false,"given":"Gilcelia Correia Santos","family":"Bernardes","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Jo\u00e3o del-Rei, Divin\u00f3polis, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8598-973X","authenticated-orcid":false,"given":"Leilismara Sousa","family":"Nogueira","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Jo\u00e3o del-Rei, Divin\u00f3polis, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3602-2645","authenticated-orcid":false,"given":"Patr\u00edcia Nessralla","family":"Alpoim","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6895-3543","authenticated-orcid":false,"given":"Melina de Barros","family":"Pinheiro","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Jo\u00e3o del-Rei, Divin\u00f3polis, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"47794","published-online":{"date-parts":[[2021,6,28]]},"reference":[{"issue":"05","key":"ref1","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/j.ajog.2020.02.017","article-title":"Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know","volume":"222","author":"S A Rasmussen","year":"2020","journal-title":"Am J Obstet Gynecol"},{"issue":"01","key":"ref2","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1016\/j.ajog.2003.11.019","article-title":"Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome","volume":"191","author":"S F Wong","year":"2004","journal-title":"Am J Obstet Gynecol"},{"issue":"02","key":"ref3","doi-asserted-by":"publisher","first-page":"194","DOI":"10.3390\/v12020194","article-title":"Potential maternal and infant outcomes from Coronavirus 2019-nCoV (SARS-CoV-2) infecting pregnant women: lessons from SARS, MERS, and other human coronavirus infections","volume":"12","author":"D A Schwartz","year":"2020","journal-title":"Viruses"},{"issue":"08","key":"ref4","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1056\/NEJMoa2001017","article-title":"A Novel Coronavirus from Patients with Pneumonia in China, 2019","volume":"382","author":"N Zhu","year":"2020","journal-title":"N Engl J Med"},{"issue":"18","key":"ref7","doi-asserted-by":"publisher","first-page":"1708","DOI":"10.1056\/NEJMoa2002032","article-title":"Clinical Characteristics of Coronavirus Disease 2019 in China","volume":"382","author":"W J Guan","year":"2020","journal-title":"N Engl J Med"},{"issue":"05","key":"ref8","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1016\/S1473-3099(20)30176-6","article-title":"Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study","volume":"20","author":"N Yu","year":"2020","journal-title":"Lancet Infect Dis"},{"volume-title":"Doen\u00e7a pelo Coronav\u00edrus COVID-19","year":"2020","author":"Minist\u00e9rio da Sa\u00fade. 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