{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T02:34:18Z","timestamp":1750818858136,"version":"3.37.3"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>\n            Objective\u2003There is wide variation in the management of pregnancies complicated by abnormal placental cord insertion (PCI), which includes velamentous cord insertion (VCI) and marginal cord insertion (MCI). We tested the hypothesis that abnormal PCI is associated with small for gestational age (SGA) infants.<\/jats:p><jats:p>\n            Study Design\u2003This is a retrospective cohort study of all pregnant patients undergoing anatomic ultrasound at a single institution from 2010 to 2017. Patients with abnormal PCI were matched in a 1:2 ratio by race, parity, gestational age at the time of ultrasound, and obesity to patients with normal PCIs. The primary outcome was SGA at delivery. Secondary outcomes were cesarean delivery, preterm delivery, cesarean delivery for nonreassuring fetal status, 5-minute Apgar score\u2009&lt;\u20097, umbilical artery pH\u2009&lt;\u20097.1, and neonatal intensive care unit admission. These outcomes were compared using univariate and bivariate analyses.<\/jats:p><jats:p>\n            Results\u2003Abnormal PCI was associated with an increased risk of SGA (relative risk [RR]: 2.43; 95% confidence interval [CI]: 1.26\u20134.69), increased risk of preterm delivery &lt;37 weeks (RR: 3.60; 95% CI: 1.74\u20137.46), and &lt;34 weeks (RR: 3.50; 95% CI: 1.05\u201311.63) compared with patients with normal PCI. There was no difference in rates of cesarean delivery, Apgar score of &lt;7 at 5\u2009minutes, acidemia, or neonatal intensive care unit admission between normal and abnormal PCI groups. In a stratified analysis, the association between abnormal PCI and SGA did not differ by the type of abnormal PCI (p for interaction\u2009=\u20090.46).<\/jats:p><jats:p>\n            Conclusion\u2003Abnormal PCI is associated with an increased risk of SGA and preterm delivery. These results suggest that serial fetal growth assessments in this population may be warranted.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0041-1729163","type":"journal-article","created":{"date-parts":[[2021,5,2]],"date-time":"2021-05-02T22:33:06Z","timestamp":1619994786000},"page":"089-094","source":"Crossref","is-referenced-by-count":5,"title":["Obstetric Outcomes in Singleton Pregnancies with Abnormal Placental Cord Insertions"],"prefix":"10.1055","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1041-1535","authenticated-orcid":false,"given":"Leilah D.","family":"Zahedi-Spung","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Washington University in St. Louis, Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Molly J.","family":"Stout","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, University of Michigan, Ann Arbor, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ebony B.","family":"Carter","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Washington University in St. Louis, Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey M.","family":"Dicke","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Washington University in St. Louis, Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Methodius G.","family":"Tuuli","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Indiana University, Indianapolis, Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nandini","family":"Raghuraman","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Washington University in St. Louis, Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,5,2]]},"reference":[{"issue":"11","key":"ref1","doi-asserted-by":"crossref","first-page":"E13","DOI":"10.1002\/jum.14831","article-title":"AIUM-ACR-ACOG-SMFM-SRU Practice Parameter for the Performance of Standard Diagnostic Obstetric Ultrasound Examinations","volume":"37","year":"2018","journal-title":"J Ultrasound Med"},{"issue":"06","key":"ref2","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1002\/uog.132","article-title":"Prenatal detection of velamentous insertion of the umbilical cord: a prospective color Doppler ultrasound study","volume":"21","author":"W Sepulveda","year":"2003","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref3","first-page":"247","volume-title":"Pathology of the umbilical cord","author":"R N Baergen","year":"2011","edition":"2nd 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