{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T02:57:07Z","timestamp":1781233027746,"version":"3.54.1"},"reference-count":32,"publisher":"Georg Thieme Verlag KG","license":[{"start":{"date-parts":[[2021,5,23]],"date-time":"2021-05-23T00:00:00Z","timestamp":1621728000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian Journal of Radiology and Imaging"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\nPurpose\u2003Intraabdominal hypertension (IAH) in acute pancreatitis (AP) may reduce tissue perfusion and impair organ function and has been shown to portend poor prognosis. We investigated the computed tomography (CT) findings in patients with AP with IAH.<\/jats:p><jats:p>\nMethods\u2003This retrospective study comprised of consecutive patients with AP from June 2016 to June 2018 in whom intraabdominal pressure (IAP) was measured. The patients who underwent a contrast-enhanced CT within 7 days of IAP measurement were included. Using a cutoff of 12 mm Hg for IAP, the patients were divided into IAH and non-IAH groups. Measures of severity and clinical outcome were evaluated. CT parameters were compared between the groups.<\/jats:p><jats:p>\nResults\u2003The IAH group comprised of 41 patients, while there were 20 patients in the non-IAH group. The IAH group was characterized by severe disease, increased incidence of organ failure, increased requirement for drainage and surgery, prolonged hospital and intensive care unit stay. The mortality was not significantly different between the two groups. On univariate analysis, the CT features that were found to be significantly different between the two groups were the presence of collection (p = 0.036), the maximum dimension of collection (p = 0.004), volume of collection (p = 0.019), biliary dilatation (p = 0.011), and the presence of moderate-to-severe pleural effusion (p = 0.009). On multivariate analysis, all these parameters except biliary dilatation were found to be statistically significant.<\/jats:p><jats:p>\nConclusion\u2003CT findings in patients with AP may suggest IAH. This can be used as an additional marker for severity of AP.<\/jats:p>","DOI":"10.1055\/s-0041-1729768","type":"journal-article","created":{"date-parts":[[2021,5,23]],"date-time":"2021-05-23T23:03:57Z","timestamp":1621811037000},"source":"Crossref","is-referenced-by-count":5,"title":["Computed Tomography Findings in Intraabdominal Hypertension in Patients with Acute Pancreatitis"],"prefix":"10.1055","author":[{"given":"Pankaj","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis and Imaging, PGIMER, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohan","family":"Kamat","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis and Imaging, PGIMER, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayanta","family":"Samanta","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, PGIMER, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harshal","family":"Mandavdhare","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, PGIMER, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishal","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, PGIMER, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saroj Kant","family":"Sinha","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, PGIMER, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usha","family":"Dutta","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, PGIMER, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakesh","family":"Kochhar","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, PGIMER, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,5,23]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1097\/mpa.0b013e318149f5bf","article-title":"Clinical relevance of intra-abdominal hypertension in patients with severe acute pancreatitis","volume":"36","author":"A Z Al-Bahrani","year":"2008","journal-title":"Pancreas"},{"issue":"22","key":"ref2","doi-asserted-by":"crossref","first-page":"3541","DOI":"10.3748\/wjg.14.3541","article-title":"Abdominal compartment syndrome in patients with severe acute pancreatitis in early stage","volume":"14","author":"H Chen","year":"2008","journal-title":"World J Gastroenterol"},{"issue":"06","key":"ref3","doi-asserted-by":"crossref","first-page":"717","DOI":"10.3748\/wjg.15.717","article-title":"Early recognition of abdominal compartment syndrome in patients with acute pancreatitis","volume":"15","author":"Z Dambrauskas","year":"2009","journal-title":"World J Gastroenterol"},{"issue":"01","key":"ref4","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.pan.2019.11.010","article-title":"Site and size of extrapancreatic necrosis are associated with clinical outcomes in patients with acute necrotizing pancreatitis","volume":"20","author":"P Gupta","year":"2020","journal-title":"Pancreatology"},{"issue":"06","key":"ref5","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1002\/jgh3.12185","article-title":"Gastrointestinal complications in acute and chronic pancreatitis","volume":"3","author":"A Bansal","year":"2019","journal-title":"JGH Open"},{"issue":"05","key":"ref6","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/j.surg.2013.12.028","article-title":"Observational study of intra-abdominal pressure monitoring in acute pancreatitis","volume":"155","author":"E L Aitken","year":"2014","journal-title":"Surgery"},{"issue":"04","key":"ref7","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.pan.2020.04.012","article-title":"Reduction of intra-abdominal pressure after percutaneous catheter drainage of pancreatic fluid collection predicts survival","volume":"20","author":"A K Singh","year":"2020","journal-title":"Pancreatology"},{"issue":"04","key":"ref8","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/S0039-6109(05)70483-7","article-title":"The abdominal compartment syndrome","volume":"76","author":"J M Burch","year":"1996","journal-title":"Surg Clin North Am"},{"issue":"01","key":"ref9","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/BF02565176","article-title":"Multisystem organ failure secondary to increased intraabdominal pressure","volume":"27","author":"H J Sugerman","year":"1999","journal-title":"Infection"},{"issue":"04","key":"ref10","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1097\/00005373-200010000-00008","article-title":"Abdominal perfusion pressure: a superior parameter in the assessment of intra-abdominal hypertension","volume":"49","author":"M L Cheatham","year":"2000","journal-title":"J Trauma"},{"issue":"01","key":"ref11","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/jgh3.12099","article-title":"Thoracic complications of pancreatitis","volume":"3","author":"P Kumar","year":"2018","journal-title":"JGH Open"},{"issue":"S 04","key":"ref12","doi-asserted-by":"crossref","first-page":"S212","DOI":"10.1097\/CCM.0b013e318168e333","article-title":"Abdominal compartment syndrome","volume":"36","author":"L Maerz","year":"2008","journal-title":"Crit Care Med"},{"issue":"12","key":"ref13","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1097\/00003246-198712000-00014","article-title":"A simple technique to accurately determine intra-abdominal pressure","volume":"15","author":"T J Iberti","year":"1987","journal-title":"Crit Care Med"},{"issue":"03","key":"ref14","doi-asserted-by":"crossref","first-page":"575","DOI":"10.2214\/ajr.173.3.10470882","article-title":"The abdominal compartment syndrome: CT findings","volume":"173","author":"P J Pickhardt","year":"1999","journal-title":"AJR Am J Roentgenol"},{"issue":"05","key":"ref15","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s00247-001-0569-3","article-title":"Abdominal compartment syndrome in children: CT findings","volume":"32","author":"M Epelman","year":"2002","journal-title":"Pediatr Radiol"},{"issue":"07","key":"ref16","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.crad.2006.11.006","article-title":"A prospective evaluation of CT features predictive of intra-abdominal hypertension and abdominal compartment syndrome in critically ill surgical patients","volume":"62","author":"A Z Al-Bahrani","year":"2007","journal-title":"Clin Radiol"},{"issue":"01","key":"ref17","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s002619900295","article-title":"Narrowing of the upper abdominal inferior vena cava in patients with elevated intraabdominal pressure","volume":"23","author":"R H Wachsberg","year":"1998","journal-title":"Abdom Imaging"},{"issue":"11","key":"ref18","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1007\/s00134-006-0349-5","article-title":"Results from the international conference of experts on intra-abdominal hypertension and abdominal compartment syndrome. I. definitions","volume":"32","author":"M LNG Malbrain","year":"2006","journal-title":"Intensive Care Med"},{"issue":"05","key":"ref19","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1007\/s00261-020-02408-7","article-title":"Radiation dose from computed tomography in patients with acute pancreatitis: an audit from a tertiary care referral hospital","volume":"45","author":"P Gupta","year":"2020","journal-title":"Abdom Radiol (NY)"},{"issue":"05","key":"ref20","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1007\/s00261-020-02473-y","article-title":"Fat-modified computed tomography severity index (CTSI) is a better predictor of severity and outcome in patients with acute pancreatitis compared with modified CTSI","volume":"45","author":"P Gupta","year":"2020","journal-title":"Abdom Radiol (NY)"},{"issue":"04","key":"ref21","first-page":"495","article-title":"Role of computed tomography in prediction of gastrointestinal fistula in patients with acute pancreatitis","volume":"82","author":"P Gupta","year":"2019","journal-title":"Acta Gastroenterol Belg"},{"issue":"07","key":"ref22","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.pan.2018.08.010","article-title":"An audit of percutaneous drainage for acute necrotic collections and walled off necrosis in patients with acute pancreatitis","volume":"18","author":"B Mallick","year":"2018","journal-title":"Pancreatology"},{"issue":"02","key":"ref23","doi-asserted-by":"crossref","first-page":"315","DOI":"10.2214\/ajr.135.2.315","article-title":"CT of ascites: differential diagnosis","volume":"135","author":"H Jolles","year":"1980","journal-title":"AJR Am J Roentgenol"},{"issue":"05","key":"ref24","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.2214\/ajr.183.5.1831261","article-title":"A modified CT severity index for evaluating acute pancreatitis: improved correlation with patient outcome","volume":"183","author":"K J Mortele","year":"2004","journal-title":"AJR Am J Roentgenol"},{"issue":"05","key":"ref25","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1007\/BF02091521","article-title":"Ascites, pleural, and pericardial effusions in acute pancreatitis. A prospective study of incidence, natural history, and prognostic role","volume":"41","author":"A Maringhini","year":"1996","journal-title":"Dig Dis Sci"},{"issue":"05","key":"ref26","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.pan.2019.06.004","article-title":"Ascites in acute pancreatitis: not a silent bystander","volume":"19","author":"J Samanta","year":"2019","journal-title":"Pancreatology"},{"issue":"01","key":"ref27","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s00268-011-1295-0","article-title":"Risk factors and outcome of intra-abdominal hypertension in patients with severe acute pancreatitis","volume":"36","author":"L Ke","year":"2012","journal-title":"World J Surg"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"Epub ahead of print","DOI":"10.1007\/ S10620\u2013020\u201306526\u20136","article-title":"Unusual sites of necrotic collections in acute necrotizing pancreatitis: association with parenchymal necrosis and clinical outcomes","volume":"\u2022\u2022\u2022","author":"P Gupta","year":"2020","journal-title":"Dig Dis Sci"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"Epub ahead of print","DOI":"10.1007\/s00261-020-02740-y","article-title":"Development and validation of a computed tomography index for assessing outcomes in patients with acute pancreatitis: \u201cSMART-CT\u201d index","volume":"\u2022\u2022\u2022","author":"P Gupta","year":"2020","journal-title":"Abdom Radiol (NY)"},{"issue":"03","key":"ref30","doi-asserted-by":"crossref","first-page":"252","DOI":"10.9738\/INTSURG-D-13-00182.1","article-title":"Mortality indicators and risk factors for intra-abdominal hypertension in severe acute pancreatitis","volume":"99","author":"J G Zhao","year":"2014","journal-title":"Int Surg"},{"issue":"12","key":"ref31","doi-asserted-by":"crossref","first-page":"3696","DOI":"10.1007\/s10620-020-06116-6","article-title":"Aggressive percutaneous catheter drainage protocol for necrotic pancreatic collections","volume":"65","author":"P Gupta","year":"2020","journal-title":"Dig Dis Sci"},{"issue":"03","key":"ref32","first-page":"2311","article-title":"Kissing catheter technique for percutaneous catheter drainage of necrotic pancreatic collections in acute pancreatitis","volume":"20","author":"P Gupta","year":"2020","journal-title":"Exp Ther Med"}],"container-title":["Indian Journal of Radiology and Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0041-1729768.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,23]],"date-time":"2021-05-23T23:04:29Z","timestamp":1621811069000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0041-1729768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,23]]},"references-count":32,"URL":"https:\/\/doi.org\/10.1055\/s-0041-1729768","relation":{},"ISSN":["0971-3026","1998-3808"],"issn-type":[{"value":"0971-3026","type":"print"},{"value":"1998-3808","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,23]]}}}