{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:33:38Z","timestamp":1740126818041,"version":"3.37.3"},"reference-count":16,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:p>\n            Objective\u2003The aim of this study was to evaluate whether a 1-hour glucose challenge test (GCT) \u2265140\u2009mg\/dL in a nondiabetic index pregnancy is associated with the development of gestational diabetes mellitus (GDM) in a subsequent pregnancy.<\/jats:p><jats:p>\n            Study Design\u2003We performed a retrospective cohort study from a single institution from June 2009 to December 2018. Women with a nondiabetic index singleton gestation who underwent a 1-hour GCT at 24 to 28 weeks and had a successive singleton delivery were included. GDM was defined by a 1-hour GCT of \u2265 200\u2009mg\/dL, \u22652 of 4 elevated values on a 3-hour GCT, or a diagnosis of GDM defined by International Classification of Disease codes in the electronic medical record. Univariable analyses were performed to evaluate the associations between an elevated 1-hour GCT result in the index pregnancy, maternal characteristics, and the development of GDM in the subsequent pregnancy. Variables found to be significant (p\u2009&lt;\u20090.05) were included in multivariable analysis.<\/jats:p><jats:p>\n            Results\u2003A total of 2,423 women were included. Of these, 340 (14.0%) had an elevated 1-hour GCT in the index pregnancy. Women with an elevated 1-hour GCT in the index pregnancy compared with those without were significantly more likely to be older, married, privately insured, of Hispanic ethnicity or Asian race, chronically hypertensive, have a higher body mass index (BMI), have a shorter inter-pregnancy interval, and to develop GDM in the subsequent pregnancy (14.4 vs. 3.3%, p\u2009&lt;\u20090.001). In multivariable analysis, an elevated 1-hour GCT (adjusted odds ratio [aOR]: 4.54, 95% confidence interval [CI]: 3.02\u20136.81), first-trimester BMI \u226530\u2009kg\/m2 in the index pregnancy (aOR: 3.10, 95% CI: 2.03\u20134.71), Asian race (aOR: 2.96, 95% CI: 1.70\u20135.12), Hispanic ethnicity (aOR: 2.11, 95% CI: 1.12\u20134.00), and increasing age (aOR: 1.07, 95% CI: 1.02\u20131.12) were significantly associated with an increased risk of GDM in the subsequent pregnancy.<\/jats:p><jats:p>\n            Conclusion\u2003An elevated 1-hour GCT in a nondiabetic index pregnancy is associated with a fourfold increased risk of GDM in a subsequent pregnancy.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0041-1729878","type":"journal-article","created":{"date-parts":[[2021,5,28]],"date-time":"2021-05-28T00:27:52Z","timestamp":1622161672000},"page":"1117-1121","source":"Crossref","is-referenced-by-count":0,"title":["Elevated Glucose Challenge Test in a Nondiabetic Index Pregnancy and Gestational Diabetes in a Subsequent Pregnancy"],"prefix":"10.1055","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0431-7585","authenticated-orcid":false,"given":"Samantha","family":"de Los Reyes","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, NorthShore University HealthSystem, Evanston, Illinois"},{"name":"Department of Obstetrics of Obstetrics and Gynecology, University of Chicago Pritzker School of Medicine, Chicago, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annie","family":"Dude","sequence":"additional","affiliation":[{"name":"Department of Obstetrics of Obstetrics and Gynecology, University of Chicago Pritzker School of Medicine, Chicago, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marci","family":"Adams","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, NorthShore University HealthSystem, Evanston, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beth","family":"Plunkett","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, NorthShore University HealthSystem, Evanston, Illinois"},{"name":"Department of Obstetrics of Obstetrics and Gynecology, University of Chicago Pritzker School of Medicine, Chicago, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmet","family":"Hirsch","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, NorthShore University HealthSystem, Evanston, Illinois"},{"name":"Department of Obstetrics of Obstetrics and Gynecology, University of Chicago Pritzker School of Medicine, Chicago, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,5,27]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1007\/s10995-014-1553-5","article-title":"Trends in prevalence of diabetes among delivery hospitalizations, United States, 1993-2009","volume":"19","author":"A Correa","year":"2015","journal-title":"Matern Child Health J"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1097\/01.AOG.0000109220.24211.BD","article-title":"False-positive 1-hour glucose challenge test and adverse perinatal outcomes","volume":"103","author":"D M Stamilio","year":"2004","journal-title":"Obstet Gynecol"},{"issue":"07","key":"ref3","first-page":"176","article-title":"Are non-diabetic women with abnormal glucose screening test at increased risk of pre-eclampsia, macrosomia and caesarian birth?","volume":"45","author":"K S Khan","year":"1995","journal-title":"J Pak Med Assoc"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1097\/AOG.0b013e3181ae8d85","article-title":"Carpenter-Coustan criteria compared with the national diabetes data group thresholds for gestational diabetes mellitus","volume":"114","author":"Y W Cheng","year":"2009","journal-title":"Obstet Gynecol"},{"issue":"09","key":"ref5","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.2337\/diacare.25.9.1625","article-title":"Prevalence of gestational diabetes mellitus detected by the national diabetes data group or the Carpenter and Coustan plasma glucose thresholds","volume":"25","author":"A Ferrara","year":"2002","journal-title":"Diabetes Care"},{"issue":"03","key":"ref6","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1097\/AOG.0b013e3181cfce4f","article-title":"Gestational weight gain and risk of gestational diabetes mellitus","volume":"115","author":"M M Hedderson","year":"2010","journal-title":"Obstet Gynecol"},{"issue":"03","key":"ref7","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1097\/AOG.0000000000001891","article-title":"Interpregnancy interval and adverse pregnancy outcomes an analysis of successive pregnancies","volume":"129","author":"G E Hanley","year":"2017","journal-title":"Obstet Gynecol"},{"issue":"01","key":"ref8","first-page":"69","article-title":"Re-examining IOM Pregnancy Weight Guidelines","volume":"78","author":"Institute of Medicine and National Research Council Committee to Reexamine IOM Pregnancy Weight Guidelines","year":"2009","journal-title":"In: Weight Gain During Pregnancy: Reexamining the Guidelines"},{"key":"ref9","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-84882-120-0_2","volume-title":"Hyperglycemia and adverse pregnancy outcome (HAPO) study: an overview","author":"L P Lowe","year":"2010"},{"issue":"04","key":"ref10","doi-asserted-by":"crossref","first-page":"339.e1","DOI":"10.1016\/j.ajog.2006.11.016","article-title":"Positive association between a single abnormal glucose tolerance test value in pregnancy and subsequent abnormal glucose tolerance","volume":"196","author":"F Corrado","year":"2007","journal-title":"Am J Obstet Gynecol"},{"key":"ref11","first-page":"CD007122","article-title":"Different strategies for diagnosing gestational diabetes to improve maternal and infant health","volume":"8","author":"D Farrar","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"issue":"09","key":"ref12","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1007\/s00125-015-3647-z","article-title":"Diagnosis of gestational diabetes mellitus: falling through the net","volume":"58","author":"C L Meek","year":"2015","journal-title":"Diabetologia"},{"issue":"11","key":"ref13","doi-asserted-by":"crossref","first-page":"4311","DOI":"10.1210\/jc.2013-2460","article-title":"Screening for gestational diabetes: a systematic review and meta-analysis","volume":"98","author":"G J Prutsky","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"issue":"05","key":"ref14","doi-asserted-by":"crossref","first-page":"495.e1","DOI":"10.1016\/j.ajog.2019.12.021","article-title":"Early gestational diabetes screening in obese women: a randomized controlled trial","volume":"222","author":"L M Harper","year":"2020","journal-title":"Am J Obstet Gynecol"},{"issue":"02","key":"ref15","doi-asserted-by":"crossref","first-page":"e49","DOI":"10.1097\/AOG.0000000000002501","article-title":"ACOG Practice Bulletin No. 190","volume":"131","author":"Committee on Practice Bulletins\u2013Obstetrics","year":"2018","journal-title":"Obstet Gynecol"},{"issue":"04","key":"ref16","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1067\/mob.2002.126979","article-title":"Screening for gestational diabetes mellitus in the subsequent pregnancy: is it worthwhile?","volume":"187","author":"G C Lu","year":"2002","journal-title":"Am J Obstet Gynecol"}],"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0041-1729878.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T22:44:41Z","timestamp":1629845081000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0041-1729878"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,27]]},"references-count":16,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2021,8,24]]},"published-print":{"date-parts":[[2021,9]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0041-1729878","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"type":"print","value":"0735-1631"},{"type":"electronic","value":"1098-8785"}],"subject":[],"published":{"date-parts":[[2021,5,27]]}}}