{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T12:57:54Z","timestamp":1740142674981,"version":"3.37.3"},"reference-count":16,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"05","license":[{"start":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T00:00:00Z","timestamp":1622592000000},"content-version":"vor","delay-in-days":32,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003Most prenatal screening programs for toxoplasmosis use immunoassays in serum samples of pregnant women. Few studies assess the accuracy of screening tests in dried blood spots, which are of easy collection, storage, and transportation. The goals of the present study are to determine the performance and evaluate the agreement between an immunoassay of dried blood spots and a reference test in the serum of pregnant women from a population-based prenatal screening program for toxoplasmosis in Brazil.<\/jats:p><jats:p>\n          Methods\u2003A cross-sectional study was performed to compare the immunoassays Imunoscreen Toxoplasmose IgM and Imunoscreen Toxoplasmose IgG (Mbiolog Diagn\u00f3sticos, Ltda., Contagem, Minas Gerais, Brazil)in dried blood spots with the enzyme-linked fluorescent assay (ELFA, BioM\u00e9rieux S.A., Lyon, France) reference standard in the serum of pregnant women from Minas Gerais Congenital Toxoplasmosis Control Program.<\/jats:p><jats:p>\n          Results\u2003The dried blood spot test was able to discriminate positive and negative results of pregnant women when compared with the reference test, with an accuracy of 98.2% for immunoglobulin G (IgG), and of 95.8% for immunoglobulin M (IgM).<\/jats:p><jats:p>\n          Conclusion\u2003Dried blood samples are easy to collect, store, and transport, and they have a good performance, making this a promising method for prenatal toxoplasmosis screening programs in countries with continental dimensions, limited resources, and a high prevalence of toxoplasmosis, as is the case of Brazil.<\/jats:p>","DOI":"10.1055\/s-0041-1730285","type":"journal-article","created":{"date-parts":[[2021,6,28]],"date-time":"2021-06-28T22:33:51Z","timestamp":1624919631000},"page":"351-356","source":"Crossref","is-referenced-by-count":0,"title":["Comparison between Enzyme Immunoassays Performed on Samples of Dried Blood and Serum for Toxoplasmosis Prenatal Screening: Population-based Study"],"prefix":"10.61622","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3117-8162","authenticated-orcid":false,"given":"B\u00e1rbara Ara\u00fajo","family":"Marques","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3319-7597","authenticated-orcid":false,"given":"Ericka Vianna Machado","family":"Carellos","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0121-1275","authenticated-orcid":false,"given":"V\u00e2nia Maria Novato","family":"Silva","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4569-7767","authenticated-orcid":false,"given":"Fernando Henrique","family":"Pereira","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9364-044X","authenticated-orcid":false,"given":"Maria Regina Lage","family":"Guerra","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Ezequiel Dias, Belo Horizonte, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9831-2800","authenticated-orcid":false,"given":"Jacqueline Ara\u00fajo Domingos","family":"Iturra","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Ezequiel Dias, Belo Horizonte, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0912-3782","authenticated-orcid":false,"given":"Jos\u00e9 N\u00e9lio","family":"Janu\u00e1rio","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3174-8663","authenticated-orcid":false,"given":"Gl\u00e1ucia Manzan Queiroz de","family":"Andrade","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"47794","published-online":{"date-parts":[[2021,6,2]]},"reference":[{"issue":"08","key":"ref1","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1590\/S0100-72032005000800002","article-title":"[Acute toxoplasmosis: study of the frequency, vertical transmission rate and the relationship between maternal-fetal diagnostic tests during pregnancy in a Central-Western state of Brazil]","volume":"27","author":"E A Figueir\u00f3-Filho","year":"2005","journal-title":"Rev Bras Ginecol 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