{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T05:54:00Z","timestamp":1760162040874,"version":"3.37.3"},"reference-count":26,"publisher":"American Academy of Audiology","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["j am acad audiol"],"published-print":{"date-parts":[[2021,7,1]]},"abstract":"<jats:p><jats:bold>Abstract<\/jats:bold>  <jats:bold>Background<\/jats:bold>\u2003Some viral infections can cause congenital or acquired unilateral or bilateral hearing loss. It is predicted that the coronavirus disease 2019 (COVID-19) virus, which can affect many systems in the body, may also have a negative effect on\n hearing. <jats:bold>Purpose<\/jats:bold>\u2003This study evaluated the effects of COVID-19 infection on pure-tone average. <jats:bold>Research Design<\/jats:bold>\u2003A case\u2010control study. <jats:bold>Materials and Methods<\/jats:bold>\u2003A total of 104 volunteers (48 control, 56 experimental group) who applied to the\n ENT clinic of Ad\u0131yaman University Training and Research Hospital were included in this study. After the detailed clinical examination and medical history, 13 volunteers of the experimental group and 5 volunteers from the control group were excluded from the study. In this way, each\n group consisted of 43 volunteers. While the experimental group consisted of patients who did not have any hearing problems before but had COVID-19. The control group consisted of healthy volunteers who did not have any hearing problems and were not infected with COV\u0130D-19. Audiological\n test was applied to all volunteers to determine their pure-tone average. On the data obtained, it was analyzed whether COVID-19 affects the pure-tone average and how it changes according to variables such as age and gender. <jats:bold>Results<\/jats:bold>\u2003The evaluation of the 43 (50.0%) COVID-19-positive\n patients and 43 (50.0%) healthy controls showed no significant differences (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05) at 250 and 500\u2009Hz, whereas at 4000, 6000, and 8000\u2009Hz, the two groups differed significantly. In addition, significant differences were found in the left and right ears\n at 1000 and 2000\u2009Hz (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). The differences between the two groups in the pure-tone average of the left and right ear were statistically significant (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). However, there were no significant sex-based differences in the pure-tone\n average between males and females (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05) <jats:bold>Conclusion<\/jats:bold>\u2003The pure-tone average of COVID-19 positive patients was significantly worse than those of the healthy control group. Thus, COVID-19 should also be considered in patients presenting with unexplained\n hearing loss. Further studies should investigate the effects of COVID-19 on hearing and the underlying pathophysiology.<\/jats:p>","DOI":"10.1055\/s-0041-1730960","type":"journal-article","created":{"date-parts":[[2021,11,30]],"date-time":"2021-11-30T23:44:58Z","timestamp":1638315898000},"page":"464-468","source":"Crossref","is-referenced-by-count":4,"title":["Evaluation of Postinfection Hearing with Audiological Tests in Patients with COVID-19: A Case\u2010Control Study"],"prefix":"10.3766","volume":"32","author":[{"given":"Mehtap","family":"Koparal","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Ad\u0131yaman University Education and Training Hospital, Ad\u0131yaman, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cuneyt","family":"Y\u0131lmazer","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Ad\u0131yaman University Education and Training Hospital, Ad\u0131yaman, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2087","reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/S1473-3099(20)30200-0","article-title":"Clinical and virological data of the first cases of COVID-19 in Europe: a case series","volume":"20","author":"F X Lescure","year":"2020","journal-title":"Lancet Infect Dis"},{"issue":"01","key":"ref2","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/s40779-020-00240-0","article-title":"The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status","volume":"7","author":"Y R Guo","year":"2020","journal-title":"Mil Med Res"},{"issue":"07","key":"ref3","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1002\/alr.22579","article-title":"Association of chemosensory dysfunction and COVID-19 in patients presenting with influenza-like symptoms","volume":"10","author":"C H Yan","year":"2020","journal-title":"Int Forum Allergy Rhinol"},{"issue":"03","key":"ref4","doi-asserted-by":"crossref","first-page":"102483","DOI":"10.1016\/j.amjoto.2020.102483","article-title":"Audiological profile of asymptomatic Covid-19 PCR-positive cases","volume":"41","author":"M WM Mustafa","year":"2020","journal-title":"Am J Otolaryngol"},{"issue":"01","key":"ref5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0196-0709(00)80117-9","article-title":"Otologic and audiologic evaluation of human immunodeficiency virus-infected patients","volume":"21","author":"S S Chandrasekhar","year":"2000","journal-title":"Am J Otolaryngol"},{"issue":"09","key":"ref6","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1001\/archotol.1986.03780090021002","article-title":"Electrocochleography and brain-stem potentials in Ramsay Hunt syndrome","volume":"112","author":"S Abramovich","year":"1986","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"12","key":"ref7","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1097\/00006454-200512000-00016","article-title":"Congenital cytomegalovirus screening","volume":"24","author":"S P Adler","year":"2005","journal-title":"Pediatr Infect Dis J"},{"issue":"02","key":"ref8","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0022-510X(73)90027-0","article-title":"Herpes zoster oticus and facial paralysis (Ramsay Hunt syndrome). 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