{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T10:52:22Z","timestamp":1779879142138,"version":"3.53.1"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003The MANTA vascular closure device (VCD) is a novel collagen plug-based VCD for large bore arteriotomies. The current literature regarding complication rates of this device is quite variable and mostly limited to relatively small case series.<\/jats:p><jats:p>\n          Methods\u2003This study is retrospective analysis of the MANTA VCD-related main access site complications according to Valve Academic Research Consortium-2 (VARC-2) criteria during the hospital stay. Particular attention was paid to the detailed analysis of multislice computed tomography with regard to the anatomy of the access vessel and the puncture site itself.<\/jats:p><jats:p>\n          Results\u2003A total of 524 patients underwent transfemoral transcatheter aortic valve implantation (TF TAVI) including the use of the MANTA device (18F) for percutaneous vascular closure. A group of 22 patients was excluded from the study due to incomplete imaging data. During the study period, we observed 28 major (5.6%) and five minor (1.0%) MANTA device-related vascular complications. There was no patient death related to these adverse events. Female gender, vessel angulation at the puncture site, and at least moderate calcification of the dorsal vessel segment were identified as independent predictors for major complications.<\/jats:p><jats:p>\n          Conclusions\u2003The MANTA device is a feasible option for vascular closure of large bore arteriotomies in patients undergoing TF TAVI or other percutaneous transfemoral interventions. Furthermore, we have identified novel predictors for device failure\/complications that should be taken into account for selection of the appropriate closure device. To our knowledge, this report is one of the largest case series analyzing the use of the MANTA VCD.<\/jats:p>","DOI":"10.1055\/s-0041-1730972","type":"journal-article","created":{"date-parts":[[2021,6,27]],"date-time":"2021-06-27T22:43:15Z","timestamp":1624833795000},"page":"084-093","source":"Crossref","is-referenced-by-count":7,"title":["Evaluation of the MANTA Vascular Closure Device in Transfemoral TAVI"],"prefix":"10.1055","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2831-0492","authenticated-orcid":false,"given":"Lukasz","family":"Kmiec","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthaeus","family":"Zerdzitzki","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christof","family":"Schmid","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurt","family":"Debl","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Sossalla","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Hilker","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Holzamer","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,6,27]]},"reference":[{"issue":"20","key":"ref1","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1016\/j.jacc.2015.03.034","article-title":"Perioperative results and complications in 15,964 transcatheter aortic valve replacements: prospective data from the GARY registry","volume":"65","author":"T Walther","year":"2015","journal-title":"J Am Coll Cardiol"},{"issue":"08","key":"ref2","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.jcin.2013.05.004","article-title":"Management of vascular access in transcatheter aortic valve replacement: part 2: vascular complications","volume":"6","author":"S Toggweiler","year":"2013","journal-title":"JACC Cardiovasc Interv"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.amjcard.2016.11.009","article-title":"Incidence, predictors, and mid-term outcomes of percutaneous closure failure after transfemoral aortic valve implantation using an expandable sheath (from the Optimized Transcatheter Valvular Intervention [OCEAN-TAVI] registry)","volume":"119","author":"Y Nara","year":"2017","journal-title":"Am J Cardiol"},{"issue":"08","key":"ref4","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1016\/j.amjcard.2016.07.045","article-title":"Frequency and effect of access-related vascular injury and subsequent vascular intervention after transcatheter aortic valve replacement","volume":"118","author":"D Dencker","year":"2016","journal-title":"Am J Cardiol"},{"issue":"03","key":"ref5","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.ejvs.2019.03.014","article-title":"Vascular complications and procedures following transcatheter aortic valve implantation","volume":"58","author":"S Raju","year":"2019","journal-title":"Eur J Vasc Endovasc Surg"},{"issue":"47","key":"ref6","doi-asserted-by":"crossref","first-page":"3370","DOI":"10.1093\/eurheartj\/ehv417","article-title":"Comparison of vascular closure devices for access site closure after transfemoral aortic valve implantation","volume":"36","author":"I M Barbash","year":"2015","journal-title":"Eur Heart J"},{"issue":"10","key":"ref7","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1016\/j.amjcard.2016.02.041","article-title":"Surgical versus percutaneous femoral access for delivery of large-bore cardiovascular devices (from the PARTNER Trial)","volume":"117","author":"J M McCabe","year":"2016","journal-title":"Am J Cardiol"},{"issue":"07","key":"ref8","doi-asserted-by":"crossref","first-page":"896","DOI":"10.4244\/EIJV12I7A147","article-title":"MANTA, a novel plug-based vascular closure device for large bore arteriotomies: technical report","volume":"12","author":"L van Gils","year":"2016","journal-title":"EuroIntervention"},{"issue":"06","key":"ref9","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.jcin.2016.12.277","article-title":"Percutaneous plug-based arteriotomy closure device for large-bore access: a multicenter prospective study","volume":"10","author":"N M Van Mieghem","year":"2017","journal-title":"JACC Cardiovasc Interv"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29439","article-title":"Dedicated plug based closure for large bore access -the MARVEL prospective registry","author":"H G Kroon","year":"2020","journal-title":"Catheter Cardiovasc Interv"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29506","article-title":"Vascular complications with a plug-based vascular closure device after transcatheter aortic valve replacement: predictors and bail-outs","author":"M P van Wiechen","year":"2021","journal-title":"Catheter Cardiovasc Interv"},{"issue":"21","key":"ref12","doi-asserted-by":"publisher","first-page":"00102","DOI":"10.1016\/j.carrev.2021.02.017","article-title":"Frequency, impact and predictors of access complications with plug-based large-bore arteriotomy closure - a patient level meta-analysis","volume":"S1553-8389","author":"R-J Nuis","year":"2021","journal-title":"Cardiovasc Revasc Med"},{"issue":"02","key":"ref13","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jcin.2020.09.052","article-title":"Suture- or plug-based large-bore arteriotomy closure: a pilot randomized controlled trial","volume":"14","author":"M P van Wiechen","year":"2021","journal-title":"JACC Cardiovasc Interv"},{"issue":"05","key":"ref14","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1002\/ccd.27595","article-title":"Impact of percutaneous femoral arteriotomy closure using the MANTA\u2122 device on vascular and bleeding complications after transcatheter aortic valve replacement","volume":"92","author":"R De Palma","year":"2018","journal-title":"Catheter Cardiovasc Interv"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.ijcard.2018.04.065","article-title":"MANTA versus ProGlide vascular closure devices in transfemoral transcatheter aortic valve implantation","volume":"263","author":"F Biancari","year":"2018","journal-title":"Int J Cardiol"},{"issue":"01","key":"ref16","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s42155-018-0026-0","article-title":"Access site complications after transfemoral aortic valve implantation - a comparison of Manta and ProGlide","volume":"1","author":"P Hoffmann","year":"2018","journal-title":"CVIR Endovasc"},{"issue":"17","key":"ref17","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1016\/j.jcin.2019.06.049","article-title":"Insights from a multidisciplinary introduction of the MANTA vascular closure device","volume":"12","author":"F Moccetti","year":"2019","journal-title":"JACC Cardiovasc Interv"},{"issue":"15","key":"ref18","doi-asserted-by":"crossref","first-page":"e1558","DOI":"10.4244\/EIJ-D-18-00769","article-title":"Propensity-matched comparison of vascular closure devices after transcatheter aortic valve replacement using MANTA versus ProGlide","volume":"14","author":"N Moriyama","year":"2019","journal-title":"EuroIntervention"},{"issue":"08","key":"ref19","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1016\/j.amjcard.2019.07.030","article-title":"Early outcomes after percutaneous closure of access site in transfemoral transcatheter valve implantation using the novel vascular closure device collagen plug-based MANTA","volume":"124","author":"L Gheorghe","year":"2019","journal-title":"Am J Cardiol"},{"issue":"07","key":"ref20","doi-asserted-by":"publisher","first-page":"e007258","DOI":"10.1161\/CIRCINTERVENTIONS.119.007258","article-title":"Pivotal clinical study to evaluate the safety and effectiveness of the MANTA percutaneous vascular closure device","volume":"12","author":"D A Wood","year":"2019","journal-title":"Circ Cardiovasc Interv"},{"issue":"12","key":"ref21","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1007\/s12471-020-01465-3","article-title":"Assessment of the MANTA closure device in transfemoral transcatheter aortic valve replacement: a single-centre observational study","volume":"28","author":"J Halim","year":"2020","journal-title":"Neth Heart J"},{"issue":"06","key":"ref22","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1093\/ejcts\/ezv095","article-title":"Multislice computed tomography-based prediction of the implantation plane in transcatheter aortic valve implantation: determination of the line of perpendicularity and the implanter's views","volume":"48","author":"A Holzamer","year":"2015","journal-title":"Eur J Cardiothorac Surg"},{"issue":"01","key":"ref24","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.jtcvs.2012.09.002","article-title":"Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document","volume":"145","author":"A P Kappetein","year":"2013","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"01","key":"ref25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jcmg.2018.12.003","article-title":"Computed tomography imaging in the context of transcatheter aortic valve implantation (TAVI)\/transcatheter aortic valve replacement (TAVR): an expert consensus document of the Society of Cardiovascular Computed Tomography","volume":"12","author":"P Blanke","year":"2019","journal-title":"JACC Cardiovasc Imaging"},{"issue":"12","key":"ref26","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.jacc.2012.07.003","article-title":"Vascular complications after transcatheter aortic valve replacement: insights from the PARTNER (Placement of AoRTic TraNscathetER Valve) trial","volume":"60","author":"P G\u00e9n\u00e9reux","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.avsg.2017.06.137","article-title":"A novel iliac morphology score predicts procedural mortality and major vascular complications in transfemoral aortic valve replacement","volume":"46","author":"J Blakeslee-Carter","year":"2018","journal-title":"Ann Vasc Surg"},{"issue":"08","key":"ref28","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.jcin.2011.03.019","article-title":"Transfemoral aortic valve implantation new criteria to predict vascular complications","volume":"4","author":"K Hayashida","year":"2011","journal-title":"JACC Cardiovasc Interv"},{"issue":"05","key":"ref29","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1002\/ccd.25488","article-title":"Predicting vascular complications during transfemoral transcatheter aortic valve replacement using computed tomography: a novel area-based index","volume":"84","author":"A Krishnaswamy","year":"2014","journal-title":"Catheter Cardiovasc Interv"},{"issue":"08","key":"ref30","doi-asserted-by":"crossref","first-page":"e0183658","DOI":"10.1371\/journal.pone.0183658","article-title":"Impact of sheath diameter of different sheath types on vascular complications and mortality in transfemoral TAVI approaches using the Proglide closure device","volume":"12","author":"Z Dimitriadis","year":"2017","journal-title":"PLoS One"}],"container-title":["The Thoracic and Cardiovascular Surgeon"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0041-1730972.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T01:26:07Z","timestamp":1678411567000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0041-1730972"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,27]]},"references-count":29,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2023,3,9]]},"published-print":{"date-parts":[[2023,3]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0041-1730972","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0171-6425","1439-1902"],"issn-type":[{"value":"0171-6425","type":"print"},{"value":"1439-1902","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,27]]}}}