{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T16:56:54Z","timestamp":1789750614484,"version":"4.0.1"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T00:00:00Z","timestamp":1649808000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\u2003Benign paroxysmal positional vertigo (BPPV) appears during the same age group in which vitamin D and calcium deficiencies are evident. Vitamin D deficiency could predispose to BPPV, since these two entities share a demineralization process.<\/jats:p><jats:p>\n          Objective\u2003To establish the otological impact of vitamin D supplementation in patients with its deficiency who suffer from BPPV.<\/jats:p><jats:p>\n          Methods\u2003This was a randomized clinical trial. A total of 35 patients with vitamin D deficiency (&lt; 30\u2009ng\/ml) and BPPV were divided into 2 groups: Group 1 (control group): treatment with repositioning maneuvers; and Group 2: treatment with repositioning maneuvers and vitamin D supplementation.<\/jats:p><jats:p>\n          Results\u2003A follow-up of between 6 and 13 months and a log rank test revealed that the probability of recurrence between the experimental groups was significantly different, with group 2 having a decreased recurrence of vertigo (p\u2009=\u20090.17). Scores in the Dizziness Handicap inventory (DHI) in patients treated with vitamin D supplementation were smaller (10\u2009\u00b1\u20099) when compared with a score of 36\u2009\u00b1\u20099 in the control group.<\/jats:p><jats:p>\n          Conclusion\u2003Plasmatic values of 25-hydroxyvitamin D have an impact in patients with BPPV, who present an improvement in their quality of life when their vitamin D levels are replaced with supplementation. Benign paroxysmal positional vertigo could stop being perceived as a purely otologic disease.<\/jats:p>","DOI":"10.1055\/s-0041-1730992","type":"journal-article","created":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T04:09:12Z","timestamp":1649909352000},"page":"e666-e670","source":"Crossref","is-referenced-by-count":11,"title":["Therapeutic Effect of the Correction of Vitamin D Deficiency in Patients with Benign Paroxysmal Positional Vertigo. A Randomized Clinical Trial"],"prefix":"10.1055","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8360-9812","authenticated-orcid":false,"given":"Jimena","family":"Mancera S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Ear Nose and Throat Department, Instituto Nacional de Rehabilitaci\u00f3n, Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Hernaiz Leonardo","sequence":"additional","affiliation":[{"name":"Ear Nose and Throat Department, Instituto Nacional de Rehabilitaci\u00f3n, Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia Kioko","family":"Ishiwara Niembro","sequence":"additional","affiliation":[{"name":"Department of Otoneurology, Instituto Nacional de Rehabilitacion Luis Guillermo Ibarra Ibarra, Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Lesser","sequence":"additional","affiliation":[{"name":"Ear Nose and Throat Department, Instituto Nacional de Rehabilitaci\u00f3n, Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,4,13]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.otorri.2014.09.003","article-title":"Benign paroxysmal positional vertigo--a review of 101 cases","volume":"66","author":"C Silva","year":"2015","journal-title":"Acta Otorrinolaringol Esp"},{"issue":"04","key":"ref2","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1007\/BF00919595","article-title":"Dizziness following head injury: a neuro-otological study","volume":"242","author":"R A Davies","year":"1995","journal-title":"J Neurol"},{"issue":"09","key":"ref3","doi-asserted-by":"publisher","first-page":"2249","DOI":"10.1007\/s00405-014-3175-3","article-title":"Low bone mineral density 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