{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T04:24:48Z","timestamp":1793679888949,"version":"4.5.1"},"reference-count":17,"publisher":"Scientific Scholar","issue":"04","license":[{"start":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T00:00:00Z","timestamp":1640908800000},"content-version":"vor","delay-in-days":30,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["South Asian J Cancer"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Introduction Head and neck cancers (HNCs) are increasing in Nepal and have become a major public health issue. This study aims to describe the trend of HNCs in a national tertiary cancer hospital in Nepal.<\/jats:p>\n                  <jats:p>Methods This was a cross-sectional study with secondary data analysis conducted at B.P Koirala Memorial Hospital, Chitwan, Nepal. The data were obtained from the medical record section and included all new HNC cases registered from 2012 to 2017. Analysis was done using Statistical Package for Social Sciences version 17. Subgroup analysis was done according to age, gender, site, and year.<\/jats:p>\n                  <jats:p>Results A total of 4,582 new HNCs were registered, of which 3,097 (67.6%) were males and 1,482 (32.4%) were females. Lip and oral cavity cancers (46.5%) were the most common HNCs followed by tonsil and pharynx (18.0%) and larynx (15.8%). The trend of HNCs shows a steady rise in incidence with difference according to the sites. HNCs were more common among males than females except for thyroid cancer. The most common age group was 60 to 74 years.<\/jats:p>\n                  <jats:p>Conclusions The trend of HNCs is increasing in Nepal especially oral cancers. Awareness of risk factors, effective screening programs, and comprehensive treatment should be focused to decrease the burden of HNCs.<\/jats:p>","DOI":"10.1055\/s-0041-1731131","type":"journal-article","created":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T18:30:21Z","timestamp":1640975421000},"page":"236-240","source":"Crossref","is-referenced-by-count":7,"title":["Trend of Head and Neck Cancers in a National Tertiary Cancer Hospital of Nepal from 2012 to 2017"],"prefix":"10.25259","volume":"10","author":[{"given":"Gambhir","family":"Shrestha","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Maharajgunj, Kathmandu, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhola","family":"Siwakoti","sequence":"additional","affiliation":[{"name":"Department of Cancer Prevention, Control and Research, B.P. Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashmi","family":"Mulmi","sequence":"additional","affiliation":[{"name":"Department of Cancer Prevention, Control and Research, B.P. Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dejkumar","family":"Gautam","sequence":"additional","affiliation":[{"name":"ENT, Head and Neck Unit, Department of Surgical Oncology, B.P. Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2021,12,31]]},"reference":[{"key":"ref1","author":"Nepal Health Research Council","year":"2019"},{"issue":"06","key":"ref4","doi-asserted-by":"crossref","first-page":"394","DOI":"10.3322\/caac.21492","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"68","author":"F Bray","year":"2018","journal-title":"CA Cancer J Clin"},{"issue":"01","key":"ref5","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s10555-005-5044-4","article-title":"Epidemiology of head and neck cancer: magnitude of the problem","volume":"24","author":"L D\u00f6brossy","year":"2005","journal-title":"Cancer Metastasis Rev"},{"issue":"02","key":"ref6","doi-asserted-by":"crossref","first-page":"e0009","DOI":"10.5041\/RMMJ.10143","article-title":"Head 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cancer: an epidemiological review focused on nutritional factors","volume":"20","author":"L Dal Maso","year":"2009","journal-title":"Cancer Causes Control"},{"issue":"02","key":"ref11","first-page":"195","article-title":"Epidemiological review of head and neck cancers in Karachi","volume":"7","author":"Y Bhurgri","year":"2006","journal-title":"Asian Pac J Cancer Prev"},{"issue":"05","key":"ref12","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1002\/jso.24545","article-title":"Head and neck cancers in India","volume":"115","author":"M Dandekar","year":"2017","journal-title":"J Surg Oncol"},{"issue":"03","key":"ref13","doi-asserted-by":"crossref","first-page":"263","DOI":"10.21053\/ceo.2015.01123","article-title":"Trends in head and neck cancer in South Korea between 1999 and 2012","volume":"9","author":"J D Suh","year":"2016","journal-title":"Clin Exp Otorhinolaryngol"},{"issue":"08","key":"ref14","doi-asserted-by":"crossref","first-page":"e0134834","DOI":"10.1371\/journal.pone.0134834","article-title":"The burden and determinants of non communicable diseases risk factors in Nepal: findings from a nationwide STEPS survey","volume":"10","author":"K K Aryal","year":"2015","journal-title":"PLoS One"},{"issue":"11","key":"ref15","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.1158\/1055-9965.EPI-06-0503","article-title":"Glutathione S-transferase polymorphisms and the synergy of alcohol and tobacco in oral, pharyngeal, and laryngeal carcinoma","volume":"15","author":"E S Peters","year":"2006","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref16","first-page":"320","article-title":"Tobacco and alcohol and the risk of head and neck cancer","volume":"70","author":"H Maier","year":"1992","journal-title":"Clin Investig"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1758-3284-1-5","article-title":"Diagnostic aids in the screening of oral cancer","volume":"1","author":"S Fedele","year":"2009","journal-title":"Head Neck Oncol"},{"key":"ref18","first-page":"85","author":"R Sankaranarayanan","year":"2015"},{"key":"ref20","author":"World Health Organization","year":"2007"}],"container-title":["South Asian Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0041-1731131.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T11:13:24Z","timestamp":1781176404000},"score":1,"resource":{"primary":{"URL":"https:\/\/journal.sajc.org\/trend-of-head-and-neck-cancers-in-a-national-tertiary-cancer-hospital-of-nepal-from-2012-to-2017\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":17,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2021,12,31]]},"published-print":{"date-parts":[[2021,12]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0041-1731131","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2278-330X","2278-4306"],"issn-type":[{"value":"2278-330X","type":"print"},{"value":"2278-4306","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12]]}}}