{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:19:59Z","timestamp":1792034399887,"version":"4.4.0"},"reference-count":49,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Plast Surg"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Tendon stores, releases, and dissipates energy to efficiently transmit contractile forces from muscle to bone. Tendon injury is exceedingly common, with the spectrum ranging from chronic tendinopathy to acute tendon rupture. Tendon generally develops according to three main steps: collagen fibrillogenesis, linear growth, and lateral growth. In the setting of injury, it also repairs and regenerates in three overlapping steps (inflammation, proliferation, and remodeling) with tendon-specific durations. Acute injury to the flexor and extensor tendons of the hand are of particular clinical importance to plastic surgeons, with tendon-specific treatment guided by the general principle of minimum protective immobilization followed by hand therapy to overcome potential adhesions. Thorough knowledge of the underlying biomechanical principles of tendon healing is required to provide optimal care to patients presenting with tendon injury.<\/jats:p>","DOI":"10.1055\/s-0041-1731632","type":"journal-article","created":{"date-parts":[[2021,7,15]],"date-time":"2021-07-15T23:02:02Z","timestamp":1626390122000},"page":"211-215","source":"Crossref","is-referenced-by-count":78,"title":["Tendon: Principles of Healing and Repair"],"prefix":"10.1055","volume":"35","author":[{"given":"Christian","family":"Chartier","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, McGill University, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"ElHawary","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, McGill University Health Centre, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aslan","family":"Baradaran","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, McGill University Health Centre, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Vorstenbosch","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, McGill University Health Centre, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liqin","family":"Xu","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, McGill University Health Centre, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnny Ionut","family":"Efanov","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,7,15]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1146\/annurev-bioeng-071811-150122","article-title":"Tendon healing: repair and regeneration","volume":"14","author":"P B Voleti","year":"2012","journal-title":"Annu Rev Biomed Eng"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1115\/1.2895704","article-title":"A comprehensive approach for studying muscle-tendon mechanics","volume":"116","author":"D Hawkins","year":"1994","journal-title":"J Biomech Eng"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jhsa.2007.09.007","article-title":"Tendon: biology, biomechanics, repair, growth factors, and evolving treatment options","volume":"33","author":"R James","year":"2008","journal-title":"J Hand Surg Am"},{"issue":"10","key":"ref4","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.2106\/00004623-199173100-00009","article-title":"Histopathological changes preceding spontaneous rupture of a tendon. 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