{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T11:08:38Z","timestamp":1770721718367,"version":"3.49.0"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"03","funder":[{"DOI":"10.13039\/501100001809","name":"Joint Funds of the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81760398"],"award-info":[{"award-number":["81760398"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"Joint Funds of the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["U1503221"],"award-info":[{"award-number":["U1503221"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program","doi-asserted-by":"crossref","award":["2017YFB1304204"],"award-info":[{"award-number":["2017YFB1304204"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100015310","name":"Natural Science Foundation of Xinjiang","doi-asserted-by":"crossref","award":["2021D01C330"],"award-info":[{"award-number":["2021D01C330"]}],"id":[{"id":"10.13039\/501100015310","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Knee Surg"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Revision total knee arthroplasty (TKA) is challenging to perform in patients with periprosthetic joint infection (PJI) due to the difficulty of eradicating the infection and potential for bone and ligamentous deficits. The current study aimed to evaluate the midterm survival of varus\u2013valgus constrained (VVC) implants used in one-stage revision TKA for chronic PJI at our institution. This retrospective analysis included 132 patients with chronic PJI who underwent one-stage revision using a VVC implant. The average follow-up was 51.6 months (range: 24\u201385 months). Five-year survival analysis was performed to set recurrent infection and mechanical failure as the end point. Hospital for special surgery (HSS) as functional outcomes was evaluated preoperatively and at the latest follow-up. A total of 12 patients (9.1%) underwent retreatment for reinfection (nine patients) and mechanical failure (three patients). The overall 5-year revision-free survival was 82.7%, the infection-free survival was 91.1%, and the mechanical failure-free survival was 98.3%. The preoperative HSS knee score improved from 35.6 points (range: 24.3\u201347.7 points) preoperatively to 76.8 points (range: 57.2\u201387.6 points) at the latest follow-up. Complications were identified in 20 patients (15.2%) which included aseptic osteolysis in 4 cases, acceptable flexion instability in 3 cases, arthrofibrosis in 2 patients, hematomas in 2 cases, calf intermuscular venous thrombosis in 6 patients, and femoral stem tip pain in 3 cases. This is the first study to report the outcomes of one-stage revision using VVC implants for knee PJI. Improved functional outcomes and good midterm survival are demonstrated at an average follow-up of 51.6 months.<\/jats:p>","DOI":"10.1055\/s-0041-1731739","type":"journal-article","created":{"date-parts":[[2021,9,14]],"date-time":"2021-09-14T16:15:24Z","timestamp":1631636124000},"page":"284-291","source":"Crossref","is-referenced-by-count":9,"title":["Midterm Survival of a Varus\u2013Valgus Constrained Implant following One-Stage Revision for Periprosthetic Joint Infection: A Single-Center Study"],"prefix":"10.1055","volume":"36","author":[{"given":"Baochao","family":"Ji","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guoqing","family":"Li","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaogang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenbo","family":"Mu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,7,16]]},"reference":[{"issue":"08","key":"ref1","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.arth.2012.02.022","article-title":"Economic burden of periprosthetic joint infection in the United States","volume":"27","author":"S M Kurtz","year":"2012","journal-title":"J Arthroplasty"},{"issue":"05","key":"ref2","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1302\/0301-620X.86B5.14887","article-title":"Infection after total knee arthroplasty","volume":"86","author":"A W Blom","year":"2004","journal-title":"J Bone Joint Surg Br"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"38","DOI":"10.2106\/JBJS.G.01686","article-title":"Risk factors for infection after knee arthroplasty. 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