{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T19:58:15Z","timestamp":1771012695981,"version":"3.50.1"},"reference-count":22,"publisher":"Georg Thieme Verlag KG","issue":"04","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["61877001"],"award-info":[{"award-number":["61877001"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Considering the complexity of lung structures and the difficulty of thoracoscopic surgery, simulation-based training is of paramount importance for junior surgeons. Here, we aim to design a high-fidelity lung model through utilizing the three-dimensional (3D) printing technology combined with synthetic materials to mimic the real human lung.<\/jats:p><jats:p>\n          Methods\u2003The 3D printed lung model was manufactured based on the computed tomography images of a randomly selected male patient. Synthetic materials were used for the construction of lung parenchyma, blood vessels, and bronchi. Then, the model was assessed in terms of its visual, tactile, and operational features by participants (the senior surgeons, junior surgeons, and medical students), who were asked to complete the specially designed survey-questionnaires.<\/jats:p><jats:p>\n          Results\u2003A 3D printed model of the right lung made of synthetic materials was successfully fabricated. Thirty subjects participated in our study (10 senior surgeons, 10 junior surgeons, and 10 medical students). The average visual evaluation scores for senior surgeons, junior surgeons, and medical students were 3.97\u2009\u00b1\u20090.61, 4.56\u2009\u00b1\u20090.58, 4.76\u2009\u00b1\u20090.49, respectively. The average tactile evaluation scores were 3.40\u2009\u00b1\u20090.50, 4.13\u2009\u00b1\u20090.68, 4.00\u2009\u00b1\u20090.64, respectively. The average operation evaluation scores were 3.33\u2009\u00b1\u20090.83, 3.93\u2009\u00b1\u20090.66, 4.03\u2009\u00b1\u20090.66, respectively. Signi\ufb01cant lower scores were obtained in the group of the senior surgeons compared with the other two groups.<\/jats:p><jats:p>\n          Conclusion\u2003A high level of fidelity was exhibited in our 3D printed lung model and it could be applied as a promising simulator for the surgical training in the future.<\/jats:p>","DOI":"10.1055\/s-0041-1731783","type":"journal-article","created":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T22:46:56Z","timestamp":1632264416000},"page":"355-360","source":"Crossref","is-referenced-by-count":9,"title":["Development of a 3D Printed Lung Model Made of Synthetic Materials for Simulation"],"prefix":"10.1055","volume":"70","author":[{"given":"Ganwei","family":"Liu","sequence":"first","affiliation":[{"name":"Peking University People's Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenjie","family":"Bian","sequence":"first","affiliation":[{"name":"Peking University People's Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guili","family":"Zu","sequence":"additional","affiliation":[{"name":"Peking University People's Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Liu","sequence":"additional","affiliation":[{"name":"Peking University People's Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guoxin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Jucheng Teaching Technology Development Co. Ltd, Yingkou, Liaoning, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changji","family":"Li","sequence":"additional","affiliation":[{"name":"Jucheng Teaching Technology Development Co. Ltd, Yingkou, Liaoning, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guanchao","family":"Jiang","sequence":"additional","affiliation":[{"name":"Peking University People's Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,9,21]]},"reference":[{"issue":"07","key":"ref1","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1007\/s12094-015-1448-y","article-title":"Long noncoding RNAs in lung cancer: what we know in 2015","volume":"18","author":"Y J Xu","year":"2016","journal-title":"Clin Transl Oncol"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3322\/caac.21208","article-title":"Cancer statistics, 2014","volume":"64","author":"R Siegel","year":"2014","journal-title":"CA Cancer J Clin"},{"issue":"06","key":"ref3","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1016\/j.athoracsur.2008.07.009","article-title":"Surgery for early-stage non-small cell lung cancer: a systematic review of the video-assisted thoracoscopic surgery versus thoracotomy approaches to lobectomy","volume":"86","author":"B A Whitson","year":"2008","journal-title":"Ann Thorac Surg"},{"issue":"04","key":"ref4","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.jtcvs.2009.11.059","article-title":"Video-assisted thoracic surgery versus open lobectomy for lung cancer: a secondary analysis of data from the American College of Surgeons Oncology Group Z0030 randomized clinical trial","volume":"139","author":"W J Scott","year":"2010","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"03","key":"ref5","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.thorsurg.2008.05.003","article-title":"Cost comparison of robotic, video-assisted thoracic surgery and thoracotomy approaches to pulmonary lobectomy","volume":"18","author":"B J Park","year":"2008","journal-title":"Thorac Surg 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Med"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.cryobiol.2020.03.003","article-title":"Feasibility, effectiveness, and safety of a novel cryo-balloon targeted lung denervation technique in an animal model","volume":"93","author":"K Wang","year":"2020","journal-title":"Cryobiology"},{"issue":"06","key":"ref10","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1007\/s11748-019-01265-6","article-title":"Investigation of surgical technique for bronchial stump closure after lobectomy in animal model","volume":"68","author":"K Makidono","year":"2020","journal-title":"Gen Thorac Cardiovasc Surg"},{"key":"ref11","first-page":"250","article-title":"A role of three-dimensional (3D) reconstruction in the classification of lung adenocarcinoma","volume":"179","author":"M L Onozato","year":"2012","journal-title":"Stud Health Technol 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Monda","year":"2018","journal-title":"Urology"},{"issue":"03","key":"ref22","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1177\/0391560317749405","article-title":"Multiple application of three-dimensional soft kidney models with localized kidney cancer: a pilot study","volume":"85","author":"P V Glybochko","year":"2018","journal-title":"Urologia"}],"container-title":["The Thoracic and Cardiovascular 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