{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T21:01:42Z","timestamp":1793826102506,"version":"4.6.1"},"reference-count":27,"publisher":"Georg Thieme Verlag KG","issue":"09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:p>\n            Objective\u2003This study aimed to compare trends and characteristics of assisted reproductive technology (ART) and non-ART perinatal deaths and to evaluate the association of perinatal mortality and method of conception (ART vs. non-ART) among ART and non-ART deliveries in Florida, Massachusetts, and Michigan from 2006 to 2011.<\/jats:p><jats:p>\n            Study Design\u2003Retrospective cohort study using linked ART surveillance and vital records data from Florida, Massachusetts, and Michigan.<\/jats:p><jats:p>\n            Results\u2003During 2006 to 2011, a total of 570 ART-conceived perinatal deaths and 25,158 non-ART conceived perinatal deaths were identified from the participating states. Overall, ART perinatal mortality rates were lower than non-ART perinatal mortality rates for both singletons (7.0\/1,000 births vs. 10.2\/1,000 births) and multiples (22.8\/1,000 births vs. 41.2\/1,000 births). At &lt;28 weeks of gestation, the risk of perinatal death among ART singletons was significantly lower than non-ART singletons (adjusted risk ratio [aRR]\u2009=\u20090.46, 95% confidence interval [CI]: 0.26\u20130.85). Similar results were observed among multiples at &lt;28 weeks of gestation (aRR\u2009=\u20090.64, 95% CI: 0.45\u20130.89).<\/jats:p><jats:p>\n            Conclusion\u2003Our findings suggest that ART use is associated with a decreased risk of perinatal deaths prior to 28 weeks of gestation, which may be explained by earlier detection and management of fetal and maternal conditions among ART-conceived pregnancies. These findings provide valuable information for health care providers, including infertility specialists, obstetricians, and pediatricians when counseling ART users on risk of treatment.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0041-1732451","type":"journal-article","created":{"date-parts":[[2021,7,20]],"date-time":"2021-07-20T00:34:33Z","timestamp":1626741273000},"page":"953-959","source":"Crossref","is-referenced-by-count":4,"title":["Assisted Reproductive Technology and Perinatal Mortality: Selected States (2006\u20132011)"],"prefix":"10.1055","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0181-4554","authenticated-orcid":false,"given":"Jeani","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujia","family":"Zhang","sequence":"additional","affiliation":[{"name":"Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheree L.","family":"Boulet","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara B.","family":"Crawford","sequence":"additional","affiliation":[{"name":"Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenn E.","family":"Copeland","sequence":"additional","affiliation":[{"name":"Michigan Department of Health and Human Services, Lansing, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Bernson","sequence":"additional","affiliation":[{"name":"Massachusetts Department of Public Health, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell S.","family":"Kirby","sequence":"additional","affiliation":[{"name":"College of Public Health, University of South Florida, Tampa, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dmitry M.","family":"Kissin","sequence":"additional","affiliation":[{"name":"Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanda D.","family":"Barfield","sequence":"additional","affiliation":[{"name":"Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for States Monitoring Assisted Reproductive Technology (SMART) Collaborative","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,7,19]]},"reference":[{"key":"ref2","volume-title":"2016 Assisted Reproductive Technology National Summary Report","author":"Centers for Disease Control and Prevention, American Society for Reproductive Medicine, Society for Assisted Reproductive Technology","year":"2018"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.ss6804a1","article-title":"Assisted reproductive technology surveillance\u2014United States, 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