{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T23:40:21Z","timestamp":1782776421308,"version":"3.54.5"},"reference-count":41,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"12","license":[{"start":{"date-parts":[[2021,12,21]],"date-time":"2021-12-21T00:00:00Z","timestamp":1640044800000},"content-version":"vor","delay-in-days":20,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003To analyze the clinical and obstetric aspects of pregnant women with COVID-19.<\/jats:p><jats:p>\n          Methods\u2003A systematic literature review in the MEDLINE\/PubMed, LILACS, SCIELO, and CNKI databases was performed from March to May 2020, with the descriptors: Pregnancy; 2019-nCov; Coronavirus; SARS-Cov-2, Covid-19. Of those chosen were original titles, without language and period restriction and that addressed pregnant women with a clinical and\/or laboratory diagnosis of COVID-19. Revisions, editorials, and duplicate titles were excluded. The Newcastle-Ottawa (NOS) and Murad et al. scales were used to assess the quality of the studies.<\/jats:p><jats:p>\n          Results\u2003We included 34 articles with 412 pregnant women infected with severe acute respiratory syndrome (SARS-Cov-2), with an average age of 27.5 years of age and 36.0 gestational weeks. The most common symptom was fever (205 [49.7%]), and 89 (21.6%) pregnant women progressed to severe viral pneumonia. Laboratory tests showed an increase in C-reactive protein (154 [37.8%]), and radiological tests showed pneumonia with peripheral ground-glass pattern (172 [51.4%]). Emergency cesarean delivery was indicated for most pregnant women, and the most common gestational complication was premature rupture of ovarian membranes (14 [3.4%;]). We detected 2 (0.5%) neonatal deaths, 2 (0.5%) stillbirths, and 1 (0.2%) maternal death.<\/jats:p><jats:p>\n          Conclusion\u2003Pregnant women with COVID-19 presented a clinical picture similar to that of non-infected pregnant women, with few obstetric or neonatal repercussions. There was a greater indication of cesarean deliveries before the disease aggravated, and there was no evidence of vertical transmission of the infection.<\/jats:p>","DOI":"10.1055\/s-0041-1733913","type":"journal-article","created":{"date-parts":[[2021,12,21]],"date-time":"2021-12-21T23:32:30Z","timestamp":1640129550000},"page":"949-960","source":"Crossref","is-referenced-by-count":12,"title":["Clinical and Obstetric Aspects of Pregnant Women with COVID-19: A Systematic Review"],"prefix":"10.61622","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4291-9843","authenticated-orcid":false,"given":"Sarah Nilkece Mesquita Ara\u00fajo Nogueira","family":"Bastos","sequence":"additional","affiliation":[{"name":"Departamento de Medicina, Universidade Federal do Delta do Parna\u00edba, Parna\u00edba, PI, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4748-3655","authenticated-orcid":false,"given":"B\u00e1rbara Louise Freire","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Departamento de Medicina, Universidade Federal do Delta do Parna\u00edba, Parna\u00edba, PI, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5955-3473","authenticated-orcid":false,"given":"Larisse Giselle Barbosa","family":"Cruz","sequence":"additional","affiliation":[{"name":"Departamento de Medicina, Universidade Federal do Delta do Parna\u00edba, Parna\u00edba, PI, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8301-0076","authenticated-orcid":false,"given":"Rayza Pereira de","family":"Souza","sequence":"additional","affiliation":[{"name":"Departamento de Medicina, Faculdade Uninassau, Parna\u00edba, PI, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3050-4635","authenticated-orcid":false,"given":"Simone Santos e","family":"Silva Melo","sequence":"additional","affiliation":[{"name":"Departamento de Medicina, Universidade Federal do Delta do Parna\u00edba, Parna\u00edba, PI, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5586-3116","authenticated-orcid":false,"given":"Caroline Camargo Bandeira da Silveira","family":"Luz","sequence":"additional","affiliation":[{"name":"Departamento de Medicina, Universidade Federal do Delta do Parna\u00edba, Parna\u00edba, PI, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"47794","published-online":{"date-parts":[[2021,12,21]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1007\/s12098-020-03263-6","article-title":"A Review of Coronavirus Disease-2019 (COVID-19)","volume":"87","author":"T Singhal","year":"2020","journal-title":"Indian J 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