{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T10:32:48Z","timestamp":1776335568395,"version":"3.51.2"},"reference-count":38,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Homeopathy"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Background\u2003Whilst warts and vitiligo are both common skin diseases, their co-morbidity is rare. Here we present a clinical case of warts with vitiligo to illustrate the utility of individualized homeopathic treatment.<\/jats:p><jats:p>Method\u2003The homeopathic medicine Sepia officinalis was prescribed, based on individualization. During follow-up, changes were documented by photographs. The non-invasive methods ORIDL (Outcome Related to Impact on Daily Living), VASI (Vitiligo Area and Scoring Index), and VETF (Vitiligo European Task Force) were used to assess treatment progress. Possible causal attribution of outcome with treatment was evaluated using the Modified Naranjo Criteria for Homeopathy (MONARCH).<\/jats:p><jats:p>Result\u2003There was a marked improvement of vitiligo, along with the disappearance of warts, as evidenced photographically. VASI and VETF scores were significantly reduced. Main complaints, as well as overall well-being, improved on the ORIDL scale (+3). The MONARCH score (+9) suggested that the clinical improvement was attributable to the homeopathic intervention.<\/jats:p><jats:p>Conclusion\u2003The study suggests a significant role for individualized homeopathic treatment in the co-morbidity of warts and vitiligo.<\/jats:p>","DOI":"10.1055\/s-0041-1733975","type":"journal-article","created":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T01:46:36Z","timestamp":1637804796000},"page":"139-146","source":"Crossref","is-referenced-by-count":6,"title":["A Co-morbid Condition of Warts and Vitiligo Treated with Individualized Homeopathy: An Evidence-Based Case Report"],"prefix":"10.1055","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9594-8811","authenticated-orcid":false,"given":"Akhyaya Kumar","family":"Prusty","sequence":"additional","affiliation":[{"name":"Regional Research Institute for Homoeopathy, Puri, Odisha, under Central Council for Research in Homoeopathy, Ministry of AYUSH, Govt. of India, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Preeti","family":"Bhandari","sequence":"additional","affiliation":[{"name":"Regional Research Institute for Homoeopathy, Puri, Odisha, under Central Council for Research in Homoeopathy, Ministry of AYUSH, Govt. of India, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,11,24]]},"reference":[{"key":"ref1","volume-title":"Illustrated Synopsis of Dermatology and Sexually Transmitted Diseases","author":"N Khanna","year":"2019","edition":"6th ed."},{"key":"ref2","first-page":"1710","article-title":"Warts (non-genital)","author":"SK-F Loo","year":"2014","journal-title":"BMJ Clin Evid"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1111\/bjd.14356","article-title":"Evidence-based management of vitiligo: summary of a Cochrane systematic review","volume":"174","author":"M Whitton","year":"2016","journal-title":"Br J Dermatol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0140-6736(14)60763-7","article-title":"Vitiligo","volume":"386","author":"K Ezzedine","year":"2015","journal-title":"Lancet"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/j.1365-2133.2011.10650.x","article-title":"New insights in segmental vitiligo: case report and review of theories","volume":"166","author":"N van Geel","year":"2012","journal-title":"Br J Dermatol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.det.2008.11.013","article-title":"Comorbidities in dermatology","volume":"27","author":"M Wakkee","year":"2009","journal-title":"Dermatol Clin"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1001\/jamadermatol.2014.3324","article-title":"Association of vitiligo and alopecia areata with atopic dermatitis: A systematic review and meta-analysis","volume":"151","author":"G C Mohan","year":"2015","journal-title":"JAMA Dermatol"},{"key":"ref8","first-page":"125","article-title":"Individualized Homoeopathic approach in a case of vitiligo with hypothyroidism\u2014a case report","volume":"4","author":"S Pandey","year":"2020","journal-title":"IJA-CARE"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"330","DOI":"10.5021\/ad.2009.21.3.330","article-title":"A case of concurrent vitiligo and psoriasis","volume":"21","author":"J M Park","year":"2009","journal-title":"Ann Dermatol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"157","DOI":"10.4103\/ijpd.IJPD_127_16","article-title":"Co-occurrence of psoriasis, vitiligo, and lichen planus in a single patient","volume":"19","author":"S Neelagiri","year":"2018","journal-title":"Indian J Paediatr Dermatol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1055\/s-0034-1392808","article-title":"Lichen planus verrucosus in an association with vitiligo","volume":"41","author":"R Petrosian","year":"2015","journal-title":"Aktuelle Derm"},{"key":"ref12","first-page":"81","article-title":"Wart with depigmented halo and generalized vitiligo","volume":"55","author":"T Ito","year":"2012","journal-title":"Yonago Acta Med"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"e214","DOI":"10.1111\/pde.12049","article-title":"Goodbye warts, hello vitiligo: Candida antigen-induced depigmentation","volume":"30","author":"E N Wilmer","year":"2013","journal-title":"Pediatr Dermatol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1111\/bjd.13310","article-title":"British Association of Dermatologists' guidelines for the management of cutaneous warts 2014","volume":"171","author":"J C Sterling","year":"2014","journal-title":"Br J Dermatol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1001\/jamadermatol.2013.755","article-title":"Duct tape for the treatment of common warts in adults","volume":"149","author":"M R Sanchez","year":"2013","journal-title":"JAMA Dermatol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1111\/j.1365-4632.2012.05654.x","article-title":"A review of applications of tea tree oil in dermatology","volume":"52","author":"N Pazyar","year":"2013","journal-title":"Int J Dermatol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"365","DOI":"10.2165\/00128071-200506060-00004","article-title":"Human papillomavirus: burden of illness and treatment cost considerations","volume":"6","author":"P A Fox","year":"2005","journal-title":"Am J Clin Dermatol"},{"key":"ref18","first-page":"250","article-title":"Homeopathic management of psoriasis\u2014a case study","volume":"6","author":"Y Bhadoriya","year":"2020","journal-title":"World J Pharm Med Res"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"75","DOI":"10.4103\/0974-7168.179145","article-title":"Homoeopathic treatment in a case of co-morbid atopic dermatitis and depressive disorder","volume":"10","author":"S Parveen","year":"2016","journal-title":"Indian J Res Homoeopath"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.12659\/AJCR.913328","article-title":"Individualized homeopathic therapy in a case of obesity, dysfunctional uterine bleeding, and autonomic dystonia","volume":"19","author":"T G Denisova","year":"2018","journal-title":"Am J Case Rep"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1186\/1472-6963-7-139","article-title":"Outcome related to impact on daily living: preliminary validation of the ORIDL instrument","volume":"7","author":"D Reilly","year":"2007","journal-title":"BMC Health Serv Res"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1001\/archderm.140.6.677","article-title":"Parametric modeling of narrowband UV-B phototherapy for vitiligo using a novel quantitative tool: the Vitiligo Area Scoring Index","volume":"140","author":"I Hamzavi","year":"2004","journal-title":"Arch Dermatol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/bjd.13432","article-title":"Vitiligo Area Scoring Index and Vitiligo European Task Force assessment: reliable and responsive instruments to measure the degree of depigmentation in vitiligo","volume":"172","author":"L Komen","year":"2015","journal-title":"Br J Dermatol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1600-0749.2006.00355.x","article-title":"The definition and assessment of vitiligo: a consensus report of the Vitiligo European Task Force","volume":"20","author":"A Ta\u00efeb","year":"2007","journal-title":"Pigment Cell Res"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1055\/s-0040-1701251","article-title":"Evaluation of the Modified Naranjo Criteria for assessing causal attribution of clinical outcome to homeopathic intervention as presented in case reports","volume":"109","author":"C D Lamba","year":"2020","journal-title":"Homeopathy"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1159\/000335827","article-title":"Is it possible to distinguish homeopathic aggravation from adverse effects? A qualitative study","volume":"19","author":"T Stub","year":"2012","journal-title":"Forsch Komplement Med"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.12659\/AJCR.905340","article-title":"Homeopathic treatment of vitiligo: a report of fourteen cases","volume":"18","author":"S Mahesh","year":"2017","journal-title":"Am J Case Rep"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"168","DOI":"10.51910\/ijhdr.v12i45.638","article-title":"Homeopathic treatment of vitiligo: an open observational pilot study","volume":"12","author":"S Ganguly","year":"2013","journal-title":"Int J High Dilution Res"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"272","DOI":"10.4103\/0974-7168.194342","article-title":"Case studies for treatment of warts with Homoeopathy","volume":"10","author":"M Shaikh","year":"2016","journal-title":"Indian J Res Homoeopath"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1055\/s-0038-1673647","article-title":"Right potency matters: a case report of homoeopathic treatment of verruca palmaris","volume":"31","author":"A Sahoo","year":"2018","journal-title":"Hom\u0153opathic Links"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"45","DOI":"10.4103\/2455-3972.184085","article-title":"Homeopathic management of warts","volume":"2","author":"P Oza","year":"2016","journal-title":"Indian J Drugs Dermatol"},{"key":"ref32","first-page":"475","article-title":"Homeopathy. Basic aspects and principles of use in dermatology","volume":"43","author":"S Pingel","year":"1992","journal-title":"Hautarzt"},{"key":"ref33","volume-title":"The Principles and Art of Cure by Homoeopathy","author":"H A Roberts","year":"2012"},{"key":"ref34","volume-title":"Organon of Medicine","author":"S Hahnemann","year":"2015"},{"key":"ref35","first-page":"1749","article-title":"Homeopathic treatment of plantar warts","volume":"146","author":"M Labrecque","year":"1992","journal-title":"CMAJ"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1159\/000246277","article-title":"Homoeopathic versus placebo therapy of children with warts on the hands: a randomized, double-blind clinical trial","volume":"193","author":"J T Kainz","year":"1996","journal-title":"Dermatology"},{"key":"ref37","first-page":"25","article-title":"Double blind placebo controlled clinical trials of homoeopathic medicines in warts and molluscum contagiosum","volume":"19","author":"R K Manchanda","year":"1997","journal-title":"CCRH Q Bull"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1055\/s-0037-1621731","article-title":"The N-of-1 clinical trial: a timely research opportunity in homeopathy","volume":"107","author":"S Ulbrich-Z\u00fcrni","year":"2018","journal-title":"Homeopathy"}],"container-title":["Homeopathy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0041-1733975.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T02:55:15Z","timestamp":1699844115000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0041-1733975"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,24]]},"references-count":38,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2022,5,19]]},"published-print":{"date-parts":[[2022,5]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0041-1733975","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1475-4916","1476-4245"],"issn-type":[{"value":"1475-4916","type":"print"},{"value":"1476-4245","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,24]]}}}