{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:37:05Z","timestamp":1740148625401,"version":"3.37.3"},"reference-count":10,"publisher":"Georg Thieme Verlag KG","issue":"S 01","license":[{"start":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T00:00:00Z","timestamp":1634083200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ortop (Sao Paulo)"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Resumo<\/jats:title><jats:p>Apesar da rela\u00e7\u00e3o entre artroplastia de quadril e o desenvolvimento de sarcoma ter sido descrita pela primeira vez na literatura h\u00e1 cerca de quarenta anos, esta associa\u00e7\u00e3o \u00e9 extremamente rara. No presente relato de caso, descrevemos a associa\u00e7\u00e3o entre implante ortop\u00e9dico e sarcoma de partes moles em um homem de 79 anos submetido a artroplastia prim\u00e1ria total do quadril (ATQ) por coxartrose h\u00e1 24 anos. Foram descritas a evolu\u00e7\u00e3o cl\u00ednica e os achados radiogr\u00e1ficos e histopatol\u00f3gicos da les\u00e3o. No intraoperat\u00f3rio da segunda cirurgia de revis\u00e3o, foi evidenciada soltura dos componentes acetabular e femoral em associa\u00e7\u00e3o com extensas \u00e1reas de necrose e de metalose. Foi realizado desbridamento da regi\u00e3o do quadril e da coxa direita e retirada dos implantes. Devido \u00e0 extens\u00e3o da les\u00e3o e da necrose, n\u00e3o foi poss\u00edvel realizar nova reconstru\u00e7\u00e3o articular. O diagn\u00f3stico histopatol\u00f3gico de sarcoma pleom\u00f3rfico indiferenciado de alto grau associado a extensas \u00e1reas de metalose foi estabelecido no tecido adjacente ao implante. O paciente evoluiu com met\u00e1stases pulmonares e faleceu 6 meses ap\u00f3s o diagn\u00f3stico. Apesar da raridade da associa\u00e7\u00e3o, os sarcomas devem ser considerados no diagn\u00f3stico diferencial das solturas ass\u00e9pticas, particularmente na presen\u00e7a de metalose no tecido peri-implantar. Pelo nosso conhecimento o per\u00edodo de lat\u00eancia de 24 anos entre a ATQ prim\u00e1ria e o estabelecimento do diagn\u00f3stico de sarcoma \u00e9 um dos mais longos relatado at\u00e9 o momento.<\/jats:p>","DOI":"10.1055\/s-0041-1735140","type":"journal-article","created":{"date-parts":[[2021,10,14]],"date-time":"2021-10-14T00:28:13Z","timestamp":1634171293000},"page":"e17-e21","source":"Crossref","is-referenced-by-count":0,"special_numbering":"S","title":["Sarcoma pleom\u00f3rfico de alto grau associado a metalose em paciente com artroplastia total do quadril"],"prefix":"10.1055","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3394-3008","authenticated-orcid":false,"given":"Roni Serra","family":"Campos","sequence":"additional","affiliation":[{"name":"Centro de Cirurgia do Quadril, Instituto Nacional de Traumatologia e Ortopedia, Rio de Janeiro, RJ, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1402-9667","authenticated-orcid":false,"given":"Walter","family":"Meohas","sequence":"additional","affiliation":[{"name":"Centro de Ortopedia Oncol\u00f3gica, Instituto Nacional de Traumatologia e Ortopedia, Rio de Janeiro, RJ, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8051-4006","authenticated-orcid":false,"given":"Artur Shioji","family":"Ferradosa","sequence":"additional","affiliation":[{"name":"Centro de Cirurgia do Quadril, Instituto Nacional de Traumatologia e Ortopedia, Rio de Janeiro, RJ, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3507-0493","authenticated-orcid":false,"given":"Anneliese Fortuna de Azevedo","family":"Freire da Costa","sequence":"additional","affiliation":[{"name":"Divis\u00e3o de Pesquisa do Instituto Nacional de Traumatologia e Ortopedia, Rio de Janeiro, RJ, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5647-2248","authenticated-orcid":false,"given":"Jo\u00e3o Antonio Matheus","family":"Guimar\u00e3es","sequence":"additional","affiliation":[{"name":"Divis\u00e3o de Pesquisa do Instituto Nacional de Traumatologia e Ortopedia, Rio de Janeiro, RJ, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2248-2410","authenticated-orcid":false,"given":"Maria Eugenia Leite","family":"Duarte","sequence":"additional","affiliation":[{"name":"Divis\u00e3o de Pesquisa do Instituto Nacional de Traumatologia e Ortopedia, Rio de Janeiro, RJ, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,10,13]]},"reference":[{"issue":"454","key":"ref1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/01.blo.0000238813.95035.1b","article-title":"The cellular and molecular biology of periprosthetic osteolysis","volume":"454","author":"P E Purdue","year":"2007","journal-title":"Clin Orthop Relat Res"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1302\/0301-620X.66B1.6319423","article-title":"Malignant fibrous histiocytoma of bone at the site of a total hip arthroplasty. 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