{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,6]],"date-time":"2023-08-06T04:02:59Z","timestamp":1691294579061},"reference-count":10,"publisher":"Scientific Scholar","license":[{"start":{"date-parts":[[2021,9,20]],"date-time":"2021-09-20T00:00:00Z","timestamp":1632096000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["ruralneuropractice.com"],"crossmark-restriction":true},"short-container-title":["JNRP"],"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p>\n<jats:bold>Background<\/jats:bold>\u2003The traditional diagnosis of lumbar radiculoplexus neuropathy (LRN) is based on a classical sequence of symptoms and targeted electrodiagnostic examination by means of electromyography. Ultrasonography reliably indicates the level of lumbar radiculopathy by assessing edema mesial to the site of compression.<\/jats:p>\n<jats:p>\n<jats:bold>Materials and Methods<\/jats:bold>\u2003This case\u2013control study was undertaken at a tertiary care hospital between July 2017 and June 2019 on 15 diabetic patients with symptoms of LRN. Fifteen healthy volunteers with no symptoms or clinical signs of LRN were included in the control group. The diameter (D) and transverse diameter (TD) of L1 nerve root (L1NR), L2NR, L3NR, and L4NR were measured, and their cross-sectional areas (CSAs) were calculated based on location in the lateral zone, where the NRs were visualized. On high-resolution ultrasonography, femoral nerve was localized lateral to the femoral artery in the femoral triangle beneath the inguinal ligament. Additionally, the CSA (calculated as CSA [mm<jats:sup>2<\/jats:sup>]\u2009=\u2009D\u2009\u00d7\u2009TD\u2009\u00d7\u2009\u03c0\/4), the diameter (mm), and transverse diameter (mm) of bilateral femoral nerves at the level of L3-L4 were calculated.<\/jats:p>\n<jats:p>\n<jats:bold>Results<\/jats:bold>\u2003The difference attributed to CSAs between affected NRs in LRN group and unaffected NRs in controls at levels L1-L4 was considered statistically significant (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Receiver operating characteristic analysis revealed mean values to be 8\u2009mm<jats:sup>2<\/jats:sup> (CSA) for L1NR, 11.2\u2009mm<jats:sup>2<\/jats:sup> (CSA) for L2NR, 13.6\u2009mm2 (CSA) for L3NR, and 17.8\u2009mm<jats:sup>2<\/jats:sup> (CSA) for L4NR. There was significant difference between \u0394CSA of LRN patients and controls at L1 to L4 levels (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). CSA measurements of lateral femoral cutaneous nerve (8\u2009mm<jats:sup>2<\/jats:sup>) and femoral nerve (58\u2009mm<jats:sup>2<\/jats:sup>) performed on high-resolution ultrasonography were significantly larger on the affected side as compared with the unaffected side.<\/jats:p>\n<jats:p>\n<jats:bold>Conclusion<\/jats:bold>\u2003Radiculoplexus neuropathy of the lumbar plexus can be reliably diagnosed on high-resolution ultrasonography that can reveal nerve thickening. The laterality of affected NRs was significantly greater in LRN group when compared with controls.<\/jats:p>","DOI":"10.1055\/s-0041-1735322","type":"journal-article","created":{"date-parts":[[2021,9,20]],"date-time":"2021-09-20T23:25:10Z","timestamp":1632180310000},"page":"792-795","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["High-Resolution Ultrasonography in the Assessment of Lumbar Radiculoplexus Neuropathy in Diabetics: Preliminary Results of a Case\u2013Control Study"],"prefix":"10.25259","volume":"12","author":[{"given":"Reddy","family":"Ravikanth","sequence":"first","affiliation":[{"name":"Department of Radiology, St. John's Hospital, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2021,9,20]]},"reference":[{"issue":"4","key":"10.1055\/s-0041-1735322\/ref-1","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1002\/mus.10080","article-title":"Diabetic and nondiabetic lumbosacral radiculoplexus neuropathies: new insights into pathophysiology and treatment","volume":"25","author":"Dyck","year":"2002","journal-title":"Muscle Nerve"},{"issue":"9","key":"10.1055\/s-0041-1735322\/ref-2","doi-asserted-by":"crossref","first-page":"823","DOI":"10.4065\/72.9.823","article-title":"Magnetic resonance imaging in cancer-related lumbosacral plexopathy","volume":"72","author":"Taylor","year":"1997","journal-title":"Mayo Clin Proc"},{"key":"10.1055\/s-0041-1735322\/ref-3","doi-asserted-by":"crossref","first-page":"S71","DOI":"10.4103\/0028-3886.250719","article-title":"High resolution ultrasonography of peripheral nerves in diabetic peripheral neuropathy","volume":"67","author":"Singh","year":"2019","journal-title":"Neurol India"},{"issue":"6","key":"10.1055\/s-0041-1735322\/ref-4","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1002\/ana.22334","article-title":"Painless diabetic motor neuropathy: a variant of diabetic lumbosacral radiculoplexus Neuropathy?","volume":"69","author":"Garces-Sanchez","year":"2011","journal-title":"Ann Neurol"},{"issue":"2","key":"10.1055\/s-0041-1735322\/ref-5","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1097\/01.nrl.0000156314.24508.ed","article-title":"Diabetic neuropathies. Classification, clinical features, and pathophysiological basis","volume":"11","author":"Sinnreich","year":"2005","journal-title":"Neurologist"},{"key":"10.1055\/s-0041-1735322\/ref-6","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1093\/brain\/124.6.1197","article-title":"Non-diabetic lumbosacral radiculoplexus neuropathy: natural history, outcome and comparison with the diabetic variety","volume":"124","author":"Dyck","year":"2001","journal-title":"Brain"},{"issue":"2","key":"10.1055\/s-0041-1735322\/ref-7","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s00401-007-0326-2","article-title":"Inflammatory mediators in diabetic and non-diabetic lumbosacral radiculoplexus neuropathy","volume":"115","author":"Kawamura","year":"2008","journal-title":"Acta Neuropathol"},{"issue":"2","key":"10.1055\/s-0041-1735322\/ref-8","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.clinph.2014.05.023","article-title":"A comparison of ultrasonographic and electrophysiologic \u2018inching\u2019 in ulnar neuropathy at the elbow","volume":"126","author":"Simon","year":"2015","journal-title":"Clin Neurophysiol"},{"issue":"9","key":"10.1055\/s-0041-1735322\/ref-9","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1002\/jcu.20065","article-title":"High-resolution sonography of compressive neuropathies of the wrist","volume":"32","author":"Bianchi","year":"2004","journal-title":"J Clin Ultrasound"},{"key":"10.1055\/s-0041-1735322\/ref-10","first-page":"479","article-title":"Neck pain, cervical radiculopathy, and cervical myelopathy: pathophysiology, natural history, and clinical evaluation","volume":"52","author":"Rao","year":"2003","journal-title":"Instr Course Lect"}],"container-title":["Journal of Neurosciences in Rural Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ruralneuropractice.com\/high-resolution-ultrasonography-in-the-assessment-of-lumbar-radiculoplexus-neuropathy-in-diabetics-preliminary-results-of-a-case-control-study\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ruralneuropractice.com\/high-resolution-ultrasonography-in-the-assessment-of-lumbar-radiculoplexus-neuropathy-in-diabetics-preliminary-results-of-a-case-control-study\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T04:40:02Z","timestamp":1691210402000},"score":1,"resource":{"primary":{"URL":"https:\/\/ruralneuropractice.com\/high-resolution-ultrasonography-in-the-assessment-of-lumbar-radiculoplexus-neuropathy-in-diabetics-preliminary-results-of-a-case-control-study\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,20]]},"references-count":10,"alternative-id":["10.1055\/s-0041-1735322"],"URL":"https:\/\/doi.org\/10.1055\/s-0041-1735322","relation":{},"ISSN":["0976-3147"],"issn-type":[{"value":"0976-3147","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,20]]},"article-number":"792"}}