{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T10:44:33Z","timestamp":1788345873931,"version":"build-2803163510"},"reference-count":17,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2021,9,14]],"date-time":"2021-09-14T00:00:00Z","timestamp":1631577600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003This study aimed to assess short-term outcomes of patients with failed aortic valve bioprosthesis undergoing valve-in-valve transcatheter aortic valve replacement (ViV-TAVR) or redo surgical aortic valve replacement (rSAVR).<\/jats:p><jats:p>\n          Methods\u2003Between 2009 and 2019, 90 patients who underwent ViV-TAVR (n\u2009=\u200973) or rSAVR (n\u2009=\u200917) due to failed aortic valve bioprosthesis fulfilled the inclusion criteria. Groups were compared regarding clinical end points, including in-hospital all-cause mortality. Patients with endocarditis and in a need of combined cardiac surgery were excluded from the study.<\/jats:p><jats:p>\n          Results\u2003ViV-TAVR patients were older (78.0\u2009\u00b1\u20097.4 vs. 62.1\u2009\u00b1\u200916.2 years, p\u2009=\u20090.012) and showed a higher prevalence of baseline comorbidities such as atrial fibrillation, diabetes mellitus, hyperlipidemia, and arterial hypertension. In-hospital all-cause mortality was higher for rSAVR than in the ViV-TAVR group (17.6 vs. 0%, p\u2009&lt;\u20090.001), whereas intensive care unit stay was more often complicated by blood transfusions for rSAVR patients without differences in cerebrovascular events. The paravalvular leak was detected in 52.1% ViV-TAVR patients compared with 0% among rSAVR patients (p\u2009&lt;\u20090.001).<\/jats:p><jats:p>\n          Conclusion\u2003ViV-TAVR can be a safe and feasible alternative treatment option in patients with degenerated aortic valve bioprosthesis. The choice of treatment should include the patient's individual characteristics considering ViV-TAVR as a standard of care.<\/jats:p>","DOI":"10.1055\/s-0041-1735476","type":"journal-article","created":{"date-parts":[[2021,9,14]],"date-time":"2021-09-14T22:49:52Z","timestamp":1631659792000},"page":"094-100","source":"Crossref","is-referenced-by-count":12,"title":["Valve-in-Valve TAVR versus Redo Surgical Aortic Valve Replacement: Early Outcomes"],"prefix":"10.1055","volume":"71","author":[{"given":"Amila","family":"Cizmic","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Heart Center Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elmar","family":"Kuhn","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Heart Center Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6941-7785","authenticated-orcid":false,"given":"Kaveh","family":"Eghbalzadeh","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Heart Center Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8490-5549","authenticated-orcid":false,"given":"Carolyn","family":"Weber","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Heart Center Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parwis Baradaran","family":"Rahmanian","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Heart Center Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matti","family":"Adam","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heart Center Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Mauri","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heart Center Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Rudolph","sequence":"additional","affiliation":[{"name":"Clinic for General and Interventional Cardiology\/Angiology, Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Baldus","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heart Center Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thorsten","family":"Wahlers","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Heart Center Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,9,14]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/j.athoracsur.2015.04.062","article-title":"Contemporary outcomes of repeat aortic valve replacement: a benchmark for transcatheter valve-in-valve procedures","volume":"100","author":"T Kaneko","year":"2015","journal-title":"Ann Thorac Surg"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1093\/icvts\/ivw300","article-title":"Transcatheter valve-in-valve implantation versus redo surgical aortic valve replacement in 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