{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T20:21:07Z","timestamp":1778617267444,"version":"3.51.4"},"reference-count":40,"publisher":"Georg Thieme Verlag KG","issue":"01","funder":[{"name":"Sydney University clinical residency research programme"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Comp Orthop Traumatol"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Objective\u2003The study aims to evaluate the biomechanical properties of feline femora with craniocaudal screw-hole defects of increasing diameter, subjected to three-point bending and torsion to failure at two different loading rates.<\/jats:p><jats:p>Study Design\u2003Eighty femoral pairs were harvested from adult cat cadavers. For each bending and torsional experiment, there were five groups (n\u2009=\u20098 pairs) of increasing craniocaudal screw-hole defects (intact, 1.5\u2009mm, 2.0\u2009mm, 2.4\u2009mm, 2.7mm). Mid-diaphyseal bicortical defects were created with an appropriate pilot drill-hole and tapped accordingly. Left and right femora of each pair were randomly assigned to a destructive loading protocol at low (10\u2009mm\/min; 0.5\u2009degrees\/s) or high rates (3,000\u2009mm\/min; 90\u2009degrees\/s) respectively. Stiffness, load\/torque-to-failure, energy-to-failure and fracture morphology were recorded.<\/jats:p><jats:p>Results\u2003Defect size to bone diameter ratio was significantly different between defect groups within bending and torsional experiments respectively (intact [0%; 0%], 1.5\u2009mm [17.8%; 17.1%], 2.0\u2009mm [22.8%; 23.5%], 2.4\u2009mm [27.8%; 27.6%], 2.7\u2009mm [31.1%; 32.4%]) (p\u2009&lt;\u20090.001). No significant differences in stiffness and load\/torque-to-failure were noted with increasing deficit sizes in all loading conditions. Screw-hole (2.7\u2009mm) defects up to 33% bone diameter had a maximum of 20% reduction in bending and torsional strength compared with intact bone at both loading rates. Stiffness and load\/torque-to-failure in both bending and torsion were increased in bones subjected to higher loading rates (p\u2009&lt;\u20090.001).<\/jats:p><jats:p>Conclusion\u2003Screw-hole defects up to 2.7 mm did not significantly reduce feline bone failure properties in this ex vivo femoral study. These findings support current screw-size selection guidelines of up to 33% bone diameter as appropriate for use in feline fracture osteosynthesis.<\/jats:p>","DOI":"10.1055\/s-0041-1735551","type":"journal-article","created":{"date-parts":[[2021,9,6]],"date-time":"2021-09-06T23:22:16Z","timestamp":1630970536000},"page":"033-046","source":"Crossref","is-referenced-by-count":3,"title":["Influence of Screw-Hole Defect Size on the Biomechanical Properties of Feline Femora in an Ex Vivo Model"],"prefix":"10.1055","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1636-8622","authenticated-orcid":false,"given":"QiCai Jason","family":"Hoon","sequence":"additional","affiliation":[{"name":"Sydney School of Veterinary Science, Faculty of Science, University of Sydney, Sydney, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tian","family":"Wang","sequence":"additional","affiliation":[{"name":"Surgical and Orthopaedic Research Laboratories, Prince of Wales Clinical School, UNSW Sydney, Randwick, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evelyn","family":"Hall","sequence":"additional","affiliation":[{"name":"Sydney School of Veterinary Science, Faculty of Science, University of Sydney, Sydney, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5023-6148","authenticated-orcid":false,"given":"William R.","family":"Walsh","sequence":"additional","affiliation":[{"name":"Surgical and Orthopaedic Research Laboratories, Prince of Wales Clinical School, UNSW Sydney, Randwick, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6207-3924","authenticated-orcid":false,"given":"Kenneth A.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Sydney School of Veterinary Science, Faculty of Science, University of Sydney, Sydney, NSW, 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