{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:43:16Z","timestamp":1740166996979,"version":"3.37.3"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T00:00:00Z","timestamp":1636588800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\u2003High-resolution computed tomography (HRCT) scans of the temporal bone are used to assess the bony erosion of the middle-ear structures whenever cholesteatoma is suspected.<\/jats:p><jats:p>\n          Objective\u2003To study the differences in HRCT Hounsfield unit (HU) index measurements of middle-ear bony structures between an ears with and without cholesteatoma.<\/jats:p><jats:p>\n          Methods\u2003A retrospective study of 59 patients who underwent surgery due to unilateral cholesteatoma. The HRCT HU index of the scutum, of three middle-ear ossicles, of the lateral semicircular canal (LSCC), and of the fallopian canal was measured in both ears. A comparison was made between the cholesteatoma and the non-cholesteatomatous ear (control). All measurements were conducted by an otolaryngologist. To assess the interobserver bias, 10% of the samples were randomly and independently assessed by another otolaryngologist and a neuroradiologist who were blinded.<\/jats:p><jats:p>\n          Results\u2003The average HU index was lower in the ear with cholesteatoma when compared with the non-cholesteatomatous ear. While the differences were statistically significant regarding the measurements of the scutum (516.02\u2009\u00b1\u2009311.693 versus 855.64\u2009\u00b1\u2009389.999; p\u2009=\u20090.001), the malleus (1049.44\u2009\u00b1\u2009481.765 versus 1413.47\u2009\u00b1\u2009313.376; p\u2009=\u20090.01), and the incus (498.03\u2009\u00b1\u2009264.184 versus 714.25\u2009\u00b1\u2009405.631; p\u2009=\u20090.001), the differences in the measurements of the LSCC (1042.34\u2009\u00b1\u2009301.066 versus 1154.53\u2009\u00b1\u2009359.609; p\u2009=\u20090.69) and of the fallopian canal (467.19\u2009\u00b1\u2009221.556 versus 543.51\u2009\u00b1\u2009263.573; p\u2009=\u20090.108) were not significantly different between both groups. The stapes was immeasurable in both groups due to its small size.<\/jats:p><jats:p>\n          Conclusion\u2003Hounsfield unit index measurements are a useful tool that may aid in the diagnosis of early-stage cholesteatoma.<\/jats:p>","DOI":"10.1055\/s-0041-1736580","type":"journal-article","created":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T23:55:42Z","timestamp":1636674942000},"page":"e414-e421","source":"Crossref","is-referenced-by-count":0,"title":["Are Hounsfield Unit Measurements of Bony Absorption Changes in Cholesteatoma Helpful?"],"prefix":"10.1055","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1760-7058","authenticated-orcid":false,"given":"Shay","family":"Shemesh","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Samson Assuta Ashdod University Hospital, Faculty of Health Sciences, Ben Gurion University, Ashdod, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Luckman","sequence":"additional","affiliation":[{"name":"Department of Radiology, Assuta Medical Centers, Faculty of Health Sciences, Ben Gurion University, Tel Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5514-4376","authenticated-orcid":false,"given":"Tal","family":"Marom","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Samson Assuta Ashdod University Hospital, Faculty of Health Sciences, Ben Gurion University, Ashdod, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4494-1470","authenticated-orcid":false,"given":"Oded","family":"Kraus","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Samson Assuta Ashdod University Hospital, Faculty of Health Sciences, Ben Gurion University, Ashdod, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5093-9310","authenticated-orcid":false,"given":"Sharon Ovnat","family":"Tamir","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Samson Assuta Ashdod University Hospital, Faculty of Health Sciences, Ben Gurion University, Ashdod, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,11,11]]},"reference":[{"key":"ref1","first-page":"854024","article-title":"Updates and knowledge gaps in cholesteatoma research","volume":"2015","author":"C L Kuo","year":"2015","journal-title":"BioMed Res Int"},{"issue":"05","key":"ref2","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1007\/s00405-019-05339-2","article-title":"Ossicular chain erosion in chronic otitis media patients with cholesteatoma or granulation tissue or without those: analysis of 915 cases","volume":"276","author":"M Akarcay","year":"2019","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s00405-018-5198-7","article-title":"Facial canal dehiscence rate: a retrospective analysis of 372 chronic otitis media cases","volume":"276","author":"M T Kalcioglu","year":"2019","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"ref4","volume-title":"Flint M. Cummings Otolaryngology Head and Neck Surgery","author":"W Paul","year":"2015","edition":"6th ed"},{"issue":"02","key":"ref5","first-page":"153","article-title":"HASTE diffusion-weighted MRI for the reliable detection of cholesteatoma","volume":"18","author":"A T Il\u0131ca","year":"2012","journal-title":"Diagn Interv Radiol"},{"issue":"02","key":"ref6","doi-asserted-by":"crossref","first-page":"221","DOI":"10.3174\/ajnr.A2052","article-title":"Neuroradiology of cholesteatomas","volume":"32","author":"K Bar\u00e1th","year":"2011","journal-title":"AJNR Am J Neuroradiol"},{"issue":"07","key":"ref7","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1007\/s00330-006-0160-2","article-title":"The value of diffusion-weighted MR imaging in the diagnosis of primary acquired and residual cholesteatoma: a surgical verified study of 100 patients","volume":"16","author":"J P Vercruysse","year":"2006","journal-title":"Eur Radiol"},{"issue":"02","key":"ref8","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1046\/j.1365-2273.2002.00538.x","article-title":"The role of computerized tomography in the preoperative assessment of chronic suppurative otitis media","volume":"27","author":"P Walshe","year":"2002","journal-title":"Clin Otolaryngol Allied Sci"},{"issue":"05","key":"ref9","first-page":"665","article-title":"Computed medical imaging. Nobel lecture, Decemberr 8, 1979","volume":"4","author":"G N Hounsfield","year":"1980","journal-title":"J Comput Assist Tomogr"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1177\/000348949510400411","article-title":"Measurements of the stapes superstructure","volume":"104","author":"D F aWengen","year":"1995","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"03","key":"ref11","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.amjoto.2010.01.008","article-title":"Usefulness of computed tomography Hounsfield unit density in preoperative detection of cholesteatoma in mastoid ad antrum","volume":"32","author":"M H Park","year":"2011","journal-title":"Am J Otolaryngol"},{"issue":"12","key":"ref12","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1177\/000348941212101204","article-title":"Is preoperative computed tomographic density measurement of soft tissues helpful in the diagnosis of cholesteatoma?","volume":"121","author":"D H Lee","year":"2012","journal-title":"Ann Otol Rhinol Laryngol"},{"volume-title":"Usefulness of Computed Tomography Hounsfield Unit Measurement for Diagnosis of Congenital Cholesteatoma","year":"2014","author":"S H Ahn","key":"ref13"},{"issue":"02","key":"ref14","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0895-6111(99)00043-9","article-title":"CT number variations due to different image acquisition and reconstruction parameters: a thorax phantom study","volume":"24","author":"R Groell","year":"2000","journal-title":"Comput Med Imaging Graph"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.ejmp.2017.11.036","article-title":"Assessment of the variation in CT scanner performance (image quality and Hounsfield units) with scan parameters, for image optimisation in radiotherapy treatment planning","volume":"45","author":"A T Davis","year":"2018","journal-title":"Phys Med"}],"container-title":["International Archives of Otorhinolaryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0041-1736580.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T00:11:56Z","timestamp":1657843916000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0041-1736580"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,11]]},"references-count":15,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2022,7,14]]},"published-print":{"date-parts":[[2022,7]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0041-1736580","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1809-9777","1809-4864"],"issn-type":[{"type":"print","value":"1809-9777"},{"type":"electronic","value":"1809-4864"}],"subject":[],"published":{"date-parts":[[2021,11,11]]}}}