{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T08:38:08Z","timestamp":1787906288239,"version":"build-2784847793"},"reference-count":10,"publisher":"Georg Thieme Verlag KG","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:p>\n            Objective\u2003The objective of our study is to determine if human immunodeficiency virus (HIV)-positive pregnant patients have a higher rate of group B streptococcus (GBS) rectovaginal colonization compared with HIV-negative pregnant patients.<\/jats:p><jats:p>\n            Study Design\u2003Our study is a multi-site retrospective study performed at Ochsner Louisiana State University-Health Shreveport and Monroe campuses including patients who delivered between December 2011and June 2019. Rates of GBS rectovaginal colonization between HIV-positive pregnant patients were compared with a control group of HIV-negative patients. The control group was age and race matched in a 2:1 fashion. The primary outcome was to investigate rates of GBS rectovaginal colonization. Secondary outcomes included GBS culture antibiotic sensitivities, presence of GBS urinary tract infection, GBS positivity based on HIV viral load, and GBS positivity based on new vs established diagnosis of HIV. Continuous data were analyzed using an unpaired t-test, and categorical data were analyzed using a Chi-squared test. The probability level of &lt;0.05 was set as statistically significant.<\/jats:p><jats:p>\n            Results\u2003A total of 225 patients were included in the final analysis, 75 HIV-positive and 150 HIV-negative controls. Demographic differences were noted. HIV-positive patients were more likely to deliver preterm and were more likely to deliver via cesarean section. Our primary outcome showed no significant differences in incidence of GBS colonization between HIV-positive patients and control group (n\u2009=\u200931, 41.3% vs n\u2009=\u200946, 30.6%, p\u2009=\u20090.136). Antibiotic resistance patterns showed no significant difference between the two groups. There were no significant differences in GBS positivity based on HIV viral load.<\/jats:p><jats:p>\n            Conclusion\u2003Our study does not show a statistically significant difference in the incidence of GBS colonization between HIV-positive patients and HIV-negative controls.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0041-1739356","type":"journal-article","created":{"date-parts":[[2021,11,16]],"date-time":"2021-11-16T23:52:56Z","timestamp":1637106776000},"page":"1573-1578","source":"Crossref","is-referenced-by-count":5,"title":["Group B Streptococcus Rectovaginal Colonization and Resistance Patterns in HIV-Positive Compared to HIV-Negative Pregnant Patients"],"prefix":"10.1055","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7821-2204","authenticated-orcid":false,"given":"John A.","family":"Morgan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Louisiana State University Health Sciences Center, Shreveport, Louisiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam E.","family":"Hankins","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Louisiana State University Health Sciences Center, Shreveport, Louisiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas A.","family":"Callais","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Louisiana State University Health Sciences Center, Shreveport, Louisiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles W.","family":"Albritton","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Louisiana State University Health Sciences Center, Shreveport, Louisiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Vanchiere","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Louisiana State University Health Sciences Center, Shreveport, Louisiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond E.","family":"Betcher","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Louisiana State University Health Sciences Center, Shreveport, Louisiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David F.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Louisiana State University Health Sciences Center, Shreveport, Louisiana"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,11,16]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"e51","DOI":"10.1097\/AOG.0000000000003668","article-title":"Prevention of group B streptococcal early-onset disease in newborns. 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American College of Obstetricians and Gynecologists","volume":"135","year":"2020","journal-title":"Obstet Gynecol"},{"key":"ref2","first-page":"1","article-title":"Prevention of perinatal group B streptococcal disease\u2013revised guidelines from CDC, 2010","volume":"59","author":"J R Verani","year":"2010","journal-title":"MMWR Recomm Rep"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"13820","DOI":"10.1038\/s41598-017-13218-1","article-title":"Role of HIV exposure and infection in relation to neonatal GBS disease and rectovaginal GBS carriage: a systematic review and meta-analysis","volume":"7","author":"P Cools","year":"2017","journal-title":"Sci Rep"},{"issue":"02","key":"ref4","doi-asserted-by":"crossref","first-page":"e20191881","DOI":"10.1542\/peds.2019-1881","article-title":"Management of infants at risk for group B streptococcal disease","volume":"144","author":"K M Puopolo","year":"2019","journal-title":"Pediatrics"},{"issue":"02","key":"ref5","doi-asserted-by":"crossref","first-page":"605","DOI":"10.4049\/jimmunol.1601355","article-title":"Inside out: HIV, the gut microbiome, and the mucosal immune system","volume":"198","author":"J Liu","year":"2017","journal-title":"J Immunol"},{"issue":"01","key":"ref6","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1097\/COH.0000000000000429","article-title":"Altered gut microbiome composition in HIV infection: causes, effects and potential intervention","volume":"13","author":"A Bandera","year":"2018","journal-title":"Curr Opin HIV AIDS"},{"issue":"11","key":"ref7","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1089\/jwh.2011.2888","article-title":"Group B streptococcus colonization by HIV status in pregnant women: prevalence and risk factors","volume":"20","author":"M Shah","year":"2011","journal-title":"J Womens Health (Larchmt)"},{"issue":"09","key":"ref8","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.3855\/jidc.5030","article-title":"Prevalence of colonization by Streptococcus agalactiae among pregnant women in Bukavu, Democratic Republic of the Congo","volume":"8","author":"K T Mitima","year":"2014","journal-title":"J Infect Dev Ctries"},{"issue":"12","key":"ref9","doi-asserted-by":"crossref","first-page":"ofy320","DOI":"10.1093\/ofid\/ofy320","article-title":"Prevalence, risk factors, and serotype distribution of group B streptococcus colonization in HIV-infected pregnant women living in Belgium: a prospective cohort study","volume":"5","author":"N Dauby","year":"2018","journal-title":"Open Forum Infect Dis"},{"issue":"09","key":"ref10","doi-asserted-by":"crossref","first-page":"742","DOI":"10.3109\/00365548.2011.585178","article-title":"Group B streptococcus in a cohort of HIV-infected pregnant women: prevalence of colonization, identification and antimicrobial susceptibility profile","volume":"43","author":"E C Joao","year":"2011","journal-title":"Scand J Infect Dis"}],"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0041-1739356.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T08:24:10Z","timestamp":1696580650000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0041-1739356"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,16]]},"references-count":10,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2023,10,5]]},"published-print":{"date-parts":[[2023,10]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0041-1739356","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,16]]}}}