{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T11:38:28Z","timestamp":1784547508605,"version":"3.55.0"},"reference-count":16,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr Surg"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Aim\u2003To assess the risk factors for anastomotic stricture (AS) in end-to-end anastomosis (EEA) in patients with esophageal atresia (EA).<\/jats:p><jats:p>\n          Methods\u2003With ethical consent, hospital records of 341 EA patients from 1980 to 2020 were reviewed. Patients with less than 3 months survival (n\u2009=\u200930) with Gross type E EA (n\u2009=\u200924) and with primary reconstruction (n\u2009=\u200921) were excluded. Outcome measures were revisional surgery for anastomotic stricture (RSAS) and number of dilatations required for anastomotic patency without RSAS. The factors that were tested for risk of RSAS or dilatations were distal tracheoesophageal fistula (TEF) at the carina in C-type EA (congenital TEF [CTEF]), type A\/B EA, antireflux surgery (ARS), anastomotic leakage, recurrent TEF, and Spitz group and congenital heart disease.<\/jats:p><jats:p>\n          Main Results\u2003A total of 266 patients, Gross type A (n\u2009=\u200917), B (n\u2009=\u20093), C (n\u2009=\u2009237), or D (n\u2009=\u20099) underwent EEA (early n\u2009=\u2009240, delayed n\u2009=\u200926). Early anastomotic breakdown required secondary reconstruction in five patients. Of the remaining 261 patients, 17 (6.1%) had RSAS, whereas 244 patients with intact end to end required a median of five (interquartile range: 2\u20138) dilatations for anastomotic patency. Main risk factors for RSAS or (&gt; 8) dilatations were CTEF, type A\/B, ARS, and anastomotic leakage that increased the risk of RSAS or dilatations from 4.6- to 11-fold.<\/jats:p><jats:p>\n          Conclusion\u2003The risk of severe AS is associated with long-gap EA, significant gastroesophageal reflux, and anastomotic leakage.<\/jats:p>","DOI":"10.1055\/s-0041-1739422","type":"journal-article","created":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T23:42:43Z","timestamp":1637883763000},"page":"056-060","source":"Crossref","is-referenced-by-count":9,"title":["Anastomotic Stricture in End-to-End Anastomosis\u2014Risk Factors in a Series of 261 Patients with Esophageal Atresia"],"prefix":"10.1055","volume":"32","author":[{"given":"Antti","family":"Koivusalo","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Children's Hospital, Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annika","family":"Mutanen","sequence":"additional","affiliation":[{"name":"Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janne","family":"Suominen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Children's Hospital, Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikko","family":"Pakarinen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Hospital for Children and Adolescents, University of Helsinki, Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,11,25]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1055\/s-0039-1693116","article-title":"ERNICA consensus conference on the management of patients with esophageal atresia and tracheoesophageal fistula: diagnostics, preoperative, operative, and postoperative management","volume":"30","author":"C Dingemann","year":"2020","journal-title":"Eur J Pediatr Surg"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.jpedsurg.2014.11.004","article-title":"Revisional surgery for recurrent tracheoesophageal fistula and anastomotic complications after repair of esophageal atresia in 258 infants","volume":"50","author":"A I Koivusalo","year":"2015","journal-title":"J Pediatr Surg"},{"issue":"03","key":"ref3","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1055\/s-0033-1347917","article-title":"Anastomotic stricture after esophageal atresia repair: a critical review of recent literature","volume":"23","author":"R Baird","year":"2013","journal-title":"Eur J Pediatr 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Endosc"},{"issue":"06","key":"ref14","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1055\/s-0032-1331459","article-title":"Long-gap esophageal atresia: a meta-analysis of jejunal interposition, colon interposition, and gastric pull-up","volume":"22","author":"G Gallo","year":"2012","journal-title":"Eur J Pediatr Surg"},{"issue":"04","key":"ref15","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1111\/dote.12047","article-title":"Refractory strictures post-esophageal atresia repair: what are the alternatives?","volume":"26","author":"D L\u00e9vesque","year":"2013","journal-title":"Dis Esophagus"},{"issue":"11","key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/dote\/doy061","article-title":"Experience with fully covered self-expandable metal stents for anastomotic stricture following esophageal atresia repair","volume":"31","author":"B Lange","year":"2018","journal-title":"Dis Esophagus"}],"container-title":["European Journal of Pediatric 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