{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T22:38:02Z","timestamp":1769553482953,"version":"3.49.0"},"reference-count":42,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:p>\n                  Objective\u2003The aim of this article was to evaluate high-frequency positive pressure ventilation (HFPPV) compared with high-frequency oscillatory ventilation (HFOV) as a rescue ventilation strategy for patients with congenital diaphragmatic hernia (CDH). HFPPV is a pressure-controlled conventional ventilation method utilizing high respiratory rate and low positive end-expiratory pressure.<\/jats:p><jats:p>\n                  Study Design\u2003Seventy-seven patients diagnosed with CDH from January 2005 to September 2019 who were treated with stepwise progression from HFPPV to HFOV versus only HFOV were included. Fisher's exact test and the Kruskal\u2013Wallis test were used to compare outcomes.<\/jats:p><jats:p>\n                  Results\u2003Patients treated with HFPPV\u2009+\u2009HFOV had higher survival to discharge (80 vs. 50%, p\u2009=\u20090.007) and to surgical intervention (95.6 vs. 68.8%, p\u2009=\u20090.003), with average age at repair 2 days earlier (p\u2009=\u20090.004). Need for extracorporeal membrane oxygenation (p\u2009=\u20090.490), inhaled nitric oxide (p\u2009=\u20090.585), supplemental oxygen (p\u2009=\u20090.341), and pulmonary hypertension medications (p\u2009=\u20090.381) were similar.<\/jats:p><jats:p>\n                  Conclusion\u2003In CDH patients who fail respiratory support with conventional ventilation, HFPPV may be used as an intermediary mode of rescue ventilation prior to HFOV without adverse effects.<\/jats:p><jats:p>\n                  Key Points\n               <\/jats:p>","DOI":"10.1055\/s-0041-1740076","type":"journal-article","created":{"date-parts":[[2021,12,17]],"date-time":"2021-12-17T01:22:00Z","timestamp":1639704120000},"page":"255-262","source":"Crossref","is-referenced-by-count":4,"title":["High-Frequency Positive Pressure Ventilation as Primary Rescue Strategy for Patients with Congenital Diaphragmatic Hernia: A Comparison to High-Frequency Oscillatory Ventilation"],"prefix":"10.1055","volume":"41","author":[{"given":"Claire","family":"Gerall","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of Surgery, Columbia University Vagelos College of Physicians and Surgeons\/NewYork-Presbyterian Morgan Stanley Children's Hospital, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron","family":"Wallman-Stokes","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Medicine, University of Vermont Medical Center\/University of Vermont Medical Center Children's Hospital, Burlington, Vermont"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Latoya","family":"Stewart","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of Surgery, Columbia University Vagelos College of Physicians and Surgeons\/NewYork-Presbyterian Morgan Stanley Children's Hospital, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Price","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of Surgery, Columbia University Vagelos College of Physicians and Surgeons\/NewYork-Presbyterian Morgan Stanley Children's Hospital, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Kabagambe","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of Surgery, Columbia University Vagelos College of Physicians and Surgeons\/NewYork-Presbyterian Morgan Stanley Children's Hospital, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weijia","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Columbia University Mailman School of Public Heath, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Hernan","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of Surgery, Columbia University Vagelos College of Physicians and Surgeons\/NewYork-Presbyterian Morgan Stanley Children's Hospital, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jen","family":"Wung","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rakesh","family":"Sahni","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons, New York, New 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