{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:23:00Z","timestamp":1792290180395,"version":"4.4.0"},"reference-count":34,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"12","license":[{"start":{"date-parts":[[2021,12,21]],"date-time":"2021-12-21T00:00:00Z","timestamp":1640044800000},"content-version":"vor","delay-in-days":20,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Objective\u2003To evaluate the mean uterine artery pulsatility index (UtAPI) in each trimester of pregnancy as a predictor of early or late pre-eclampsia (PE) in Colombian pregnant women.<\/jats:p><jats:p>Methods\u2003The UtAPI was measured in singleton pregnancies in each trimester. Uterine artery pulsatility index as predictor of PE was evaluated by odds ratio (OR), receiver operating characteristic (ROC) curves, and Kaplan-Meier diagram.<\/jats:p><jats:p>Results\u2003Analysis in the 1st and 3rd trimester showed that abnormal UtAPI was associated with early PE (OR: 5.99: 95% confidence interval [CI]: 1.64\u201321.13; and OR: 10.32; 95%CI: 2.75\u201342.49, respectively). Sensitivity and specificity were 71.4 and 79.6%, respectively, for developing PE (area under the curve [AUC]: 0.922). The Kaplan-Meier curve showed that a UtAPI of 0.76 (95%CI: 0.58\u20131.0) in the 1st trimester was associated with early PE, and a UtAPI of 0.73 (95%CI: 0.55\u20130.97) in the 3rd trimester was associated with late PE.<\/jats:p><jats:p>Conclusion\u2003Uterine arteries proved to be a useful predictor tool in the 1st and 3rd trimesters for early PE and in the 3rd trimester for late PE in a pregnant population with high prevalence of PE.<\/jats:p>","DOI":"10.1055\/s-0041-1740273","type":"journal-article","created":{"date-parts":[[2021,12,21]],"date-time":"2021-12-21T23:32:30Z","timestamp":1640129550000},"page":"904-910","source":"Crossref","is-referenced-by-count":6,"title":["Uterine Artery Pulsatility Index as a Pre-eclampsia Predictor in the 3 Trimesters in Women with Singleton Pregnancies"],"prefix":"10.61622","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3500-0783","authenticated-orcid":false,"given":"Yuly Natalia","family":"Guzm\u00e1n","sequence":"additional","affiliation":[{"name":"Universidad El Bosque, El Bosque Research Group of Maternal Fetal Medicine and Gynecology, Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5987-8633","authenticated-orcid":false,"given":"Montserrat","family":"Uriel","sequence":"additional","affiliation":[{"name":"Universidad El Bosque, El Bosque Research Group of Maternal Fetal Medicine and Gynecology, Ecodiagn\u00f3stico El Bosque SAS, Los Cobos Medical Center, Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0800-1388","authenticated-orcid":false,"given":"Alexandra Porras","family":"Ram\u00edrez","sequence":"additional","affiliation":[{"name":"Universidad El Bosque, Research Group Community Medicine and Collective Health, Los Cobos Medical Center, Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7040-2705","authenticated-orcid":false,"given":"Ximena Carolina","family":"Romero","sequence":"additional","affiliation":[{"name":"Universidad El Bosque, El Bosque Research Group of Maternal Fetal Medicine and Gynecology, Ecodiagn\u00f3stico El Bosque SAS, Los Cobos Medical Center, Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"47794","published-online":{"date-parts":[[2021,12,21]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1002\/uog.14789","article-title":"Uterine artery pulsatility index in the three trimesters of pregnancy: effects of maternal characteristics and medical history","volume":"45","author":"A Tayyar","year":"2015","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"06","key":"ref2","doi-asserted-by":"publisher","first-page":"e323","DOI":"10.1016\/S2214-109X(14)70227-X","article-title":"Global causes of maternal death: a WHO systematic analysis","volume":"2","author":"L Say","year":"2014","journal-title":"Lancet Glob Health"},{"issue":"03","key":"ref3","doi-asserted-by":"publisher","first-page":"160","DOI":"10.18597\/rcog.3075","article-title":"Expectant management in non-severe pre-eclampsia obstetric and perinatal outcomes in a high complexity hospital in Neiva (Colombia)","volume":"69","author":"Y N Guzm\u00e1n-Yara","year":"2018","journal-title":"Rev Colomb Obstet Ginecol"},{"issue":"03","key":"ref4","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1159\/000338470","article-title":"A competing risks model in early screening for preeclampsia","volume":"32","author":"D Wright","year":"2012","journal-title":"Fetal Diagn Ther"},{"issue":"04","key":"ref5","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1002\/uog.18816","article-title":"ASPRE trial: performance of screening for preterm pre-eclampsia","volume":"50","author":"D L Rolnik","year":"2017","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"04","key":"ref6","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.preghy.2016.04.007","article-title":"The utility of first trimester uterine artery Doppler, placental volume and PAPP-A levels alone and in combination to predict preeclampsia","volume":"6","author":"B Y\u00fccel","year":"2016","journal-title":"Pregnancy Hypertens"},{"issue":"06","key":"ref7","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1002\/uog.17455","article-title":"Multicenter screening for pre-eclampsia by maternal factors and biomarkers at 11-13 weeks' gestation: comparison with NICE guidelines and ACOG recommendations","volume":"49","author":"N O'Gorman","year":"2017","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"06","key":"ref8","doi-asserted-by":"publisher","first-page":"e237","DOI":"10.1097\/AOG.0000000000003891","article-title":"Gestational hypertension and preeclampsia. 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