{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T23:21:22Z","timestamp":1772234482345,"version":"3.50.1"},"reference-count":17,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:p>\n            Objective\u2003The objective of this paper was to describe peri-procedural events and complications of infants requiring laser photocoagulation for retinopathy of prematurity (ROP) in a level IV neonatal intensive care unit.<\/jats:p><jats:p>\n            Study Design\u2003A retrospective chart review was performed of neonates requiring ROP exams from January 2017 to August 2020. Baseline maternal and neonatal characteristics, ROP exam findings, and associated treatment were analyzed. Group characteristics were compared based on the need for laser photocoagulation. Subgroup analysis of the laser group including respiratory outcomes, cardiorespiratory index (CRI) scores, and pain scores was also performed.<\/jats:p><jats:p>\n            Results\u2003Neonatal and maternal characteristics in the laser (n\u2009=\u200927) and non-laser (n\u2009=\u2009172) groups were assessed. Of the 81.5% (22\/27) that required re-intubation for laser, 36% (8\/22) had &gt;1 intubation and 18% (4\/22) had &gt;1 extubation attempt. The average duration of intubation following laser was 2.46\u2009\u00b1\u20097.13 days, with 40% (9\/22) needing peri-extubation steroids and 18% (4\/22) racemic epinephrine to facilitate extubation. Mean total respiratory support time post-laser was 8.65\u2009\u00b1\u200915.23 days. Mean neonatal pain, agitation, and sedation scores after laser were zero immediately after the procedure, 0.09\u2009\u00b1\u20090.33 at 12\u2009hours, 0.11\u2009\u00b1\u20090.47 at 24\u2009hours, and 0.11\u2009\u00b1\u20090.51 at 48\u2009hours. The mean CRI scores were 1\u2009\u00b1\u20090 immediately after the procedure, 1.17\u2009\u00b1\u20090.4 at 12\u2009hours, 1.41\u2009\u00b1\u20090.20 at 24\u2009hours, and 1\u2009\u00b1\u20090 at 48\u2009hours.<\/jats:p><jats:p>\n            Conclusion\u2003Nearly all infants undergoing laser photocoagulation for ROP in our cohort required intubation and continued respiratory support. Despite stability during the procedure, complications from intubation were common.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0041-1740347","type":"journal-article","created":{"date-parts":[[2021,12,11]],"date-time":"2021-12-11T00:05:49Z","timestamp":1639181149000},"page":"439-444","source":"Crossref","is-referenced-by-count":4,"title":["Respiratory Complications in Infants with Retinopathy of Prematurity (ROP) Requiring Laser Photocoagulation"],"prefix":"10.1055","volume":"41","author":[{"given":"Novisi","family":"Arthur","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, St. Christopher's Hospital for Children, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9740-6899","authenticated-orcid":false,"given":"Emma","family":"Byrne","sequence":"additional","affiliation":[{"name":"Drexel University College of Medicine, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Folasade","family":"Kehinde","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, St. Christopher's Hospital for Children, Philadelphia, Pennsylvania"},{"name":"Drexel University College of Medicine, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vineet","family":"Bhandari","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, St. Christopher's Hospital for Children, Philadelphia, Pennsylvania"},{"name":"Drexel University College of Medicine, Philadelphia, Pennsylvania"},{"name":"Division of Neonatology, Department of Pediatrics, The Children's Regional Hospital at Cooper, Cooper University Healthcare, Camden, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vilmaris","family":"Quinones Cardona","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, St. Christopher's Hospital for Children, Philadelphia, Pennsylvania"},{"name":"Drexel University College of Medicine, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,12,10]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1016\/S0140-6736(13)60178-6","article-title":"Retinopathy of prematurity","volume":"382","author":"A Hellstr\u00f6m","year":"2013","journal-title":"Lancet"},{"issue":"20","key":"ref2","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s40942-018-0125-z","article-title":"Incidence and risk factors for retinopathy of prematurity: a retrospective cohort study","volume":"4","author":"A M Freitas","year":"2018","journal-title":"Int J Retina 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