{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T17:06:45Z","timestamp":1751216805965,"version":"3.37.3"},"reference-count":34,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"01","license":[{"start":{"date-parts":[[2022,1,29]],"date-time":"2022-01-29T00:00:00Z","timestamp":1643414400000},"content-version":"vor","delay-in-days":28,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003To compare the perinatal outcomes of fetuses with isolated congenital diaphragmatic hernia after fetal endoscopic tracheal occlusion (FETO) and antenatal expectant management.<\/jats:p><jats:p>\n          Data sources\u2003In this rapid review, searches were conducted in the MEDLINE, PMC, EMBASE and CENTRAL databases between August 10th and September 4th, 2020. Randomized controlled trials (RCTs), quasi-RCTs or cluster-RCTs published in English in the past ten years were included.<\/jats:p><jats:p>\n          Study selection\u2003We retrieved 203 publications; 180 studies were screened by abstract. Full-text selection was performed for eight studies, and 1 single center RCT met the inclusion criteria (41 randomized women; 20 in the FETO group, and 21 in the control group).<\/jats:p><jats:p>\n          Data collection\u2003Data collection was performed independently, by both authors, in two steps (title and abstract and full-text reading).<\/jats:p><jats:p>\n          Data synthesis\u2003There were no cases of maternal mortality. The mean gestational age at delivery was of 35.6\u2009\u00b1\u2009\u20092.4 weeks in the intervention group, and of 37.4\u2009\u00b1\u2009\u20091.9 weeks among the controls (p\u2009&lt;\u20090.01). Survival until 6 months of age was reported in 50% of the intervention group, and in 5.8% of the controls (p\u2009&lt;\u20090.01; relative risk: 10.5; 95% confidence interval [95%CI]: 1.5\u201374.7). Severe postnatal pulmonary hypertension was found in 50% of the infants in the intervention group, and in 85.7% of controls (p = 0.02; relative risk: 0.6; 95%CI: 0.4\u20130.9). An analysis of the study indicated some concerns of risk of bias. The quality of evidence was considered moderate to low.<\/jats:p><jats:p>\n          Conclusion\u2003Current evidence is limited but suggests that FETO may be an effective intervention to improve perinatal outcomes.<\/jats:p>","DOI":"10.1055\/s-0041-1740596","type":"journal-article","created":{"date-parts":[[2022,1,29]],"date-time":"2022-01-29T23:30:32Z","timestamp":1643499032000},"page":"074-082","source":"Crossref","is-referenced-by-count":1,"title":["Perinatal Outcomes after Fetal Endoscopic Tracheal Occlusion for Isolated Congenital Diaphragmatic Hernia: Rapid Review"],"prefix":"10.61622","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2708-350X","authenticated-orcid":false,"given":"Juliana","family":"da-Costa-Santos","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Universidade Estadual de Campinas, Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2607-0720","authenticated-orcid":false,"given":"Jo\u00e3o Renato","family":"Bennini","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Universidade Estadual de Campinas, Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"47794","published-online":{"date-parts":[[2022,1,29]]},"reference":[{"issue":"09","key":"ref2","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1002\/pd.5297","article-title":"Proposal for standardized prenatal ultrasound assessment of the fetus with congenital diaphragmatic hernia by the European reference network on rare inherited and congenital anomalies (ERNICA)","volume":"38","author":"F M Russo","year":"2018","journal-title":"Prenat Diagn"},{"issue":"04","key":"ref3","doi-asserted-by":"publisher","first-page":"E103","DOI":"10.1503\/cmaj.170206","article-title":"Diagnosis and 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