{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T20:53:55Z","timestamp":1761598435359,"version":"3.37.3"},"reference-count":10,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg A Cent Eur Neurosurg"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Spinal cord injury (SCI) is a significant medical condition associated with various secondary complications, including cholelithiasis. Cholelithiasis can cause biliary duct obstruction and result in acute cholecystitis. The development of acute cholecystitis in SCI patients has been well studied in the Taiwanese population, showing an increased risk of acute cholecystitis in patients with SCI. The development of cholecystitis has not been well studied in the United States.<\/jats:p><jats:p>\n          Materials and Methods\u2003A retrospective review was performed on 3,939 propensity score-matched patients aged 18 to 85 years who had SCI\/surgery from 2000 to 2019. Patients were divided based on the development of postoperative complications, specifically cholecystitis with cholecystectomy.<\/jats:p><jats:p>\n          Results\u2003SCI consisted of quadriplegia (42%), paraplegia (53%), unspecified lesion of cervical spinal cord (3%), and thoracic spinal cord (2%). All groups were comparable regarding age, gender, body mass index, smoking status, and Charlson comorbidity Index. The incidence of acute cholecystitis with subsequent cholecystectomy among patients with SCI was 43.0 per 10,000 person-years (95% confidence interval: 41.51\u201344.49). Median follow-up was 36 months. The development of cholecystitis was comparable among females (54.5%) and males (45.5%), and among African Americans (52.5%) and Caucasians (47.5%).<\/jats:p><jats:p>\n          Conclusion\u2003There is an association between SCI and development of acute cholecystitis among U.S. patients. As SCI patients do not present with the classic signs of biliary colic, risk assessment for the development of acute cholecystitis will guide patient management and allow neurosurgeons to weigh the risks and benefits of prophylactic treatment for gallbladder complications.<\/jats:p>","DOI":"10.1055\/s-0041-1740617","type":"journal-article","created":{"date-parts":[[2022,5,29]],"date-time":"2022-05-29T22:34:25Z","timestamp":1653863665000},"page":"478-480","source":"Crossref","is-referenced-by-count":2,"title":["Acute Cholecystitis: An Emerging Complication in Spinal Cord Injury Patients in the United States"],"prefix":"10.1055","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4948-9292","authenticated-orcid":false,"given":"Ariella","family":"Gartenberg","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Albert Einstein College of Medicine\/Montefiore Medical center, Bronx, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Nessim","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Albert Einstein College of Medicine\/Montefiore Medical center, Bronx, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5134-301X","authenticated-orcid":false,"given":"Woojin","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Albert Einstein College of Medicine\/Montefiore Medical center, Bronx, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,5,29]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"24","DOI":"10.5312\/wjo.v6.i1.24","article-title":"Chronic complications of spinal cord injury","volume":"6","author":"N Sezer","year":"2015","journal-title":"World J 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Primer to Develop Analytic Intuition for Medical Homes and Population Health","year":"2015","author":"E Bellin","key":"ref9"},{"issue":"08","key":"ref10","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1097\/ACM.0b013e3181df0f3b","article-title":"Democratizing information creation from health care data for quality improvement, research, and education: the Montefiore Medical Center Experience","volume":"85","author":"E Bellin","year":"2010","journal-title":"Acad Med"}],"container-title":["Journal of Neurological Surgery Part A: Central European 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