{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:29:45Z","timestamp":1777501785838,"version":"3.51.4"},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Intraoperative and postoperative bleeding associated with allogeneic blood transfusion and reoperation is still a common and feared complication in patients undergoing surgery due to acute Type A Aortic Dissection (aTAAD). The aim of our study was to identify risk factors for higher transfusion rates.<\/jats:p><jats:p>\n          Methods\u2003In this retrospective single center study we evaluated pre -, intra-, and postoperative data of 121 patients with aTAAD. Depending on the median of received packed red blood cells (PRBCs), patients were divided into Group A (&lt;8 PRBC, n\u2009=\u200953) and Group B (\u22658 PRBC n\u2009=\u200968). Statistical analyses (descriptive statistics, univariable and multivariable logistic regression) were performed using SPSS software 25.0. Statistical significance was assumed at p-value &lt;0.05.<\/jats:p><jats:p>\n          Results\u2003A total of 120 patients received a blood product during their perioperative course. Among others we identified age, hemorrhagic pericardial effusion, and dual antiplatelet therapy as preoperative risk factors, low rectal temperature as intraoperative risk factor and low body temperature, positive fluid balance, high lactate level and beginning development of acute renal failure as postoperative risk factors.<\/jats:p><jats:p>\n          Conclusion\u2003Our study identifies several factors which predict a higher likelihood of bleeding and consecutive blood transfusion. Knowledge of these factors could influence the therapy to reduce transfusion requirements and lead to a targeted and more efficient use of coagulation products.<\/jats:p>","DOI":"10.1055\/s-0041-1741004","type":"journal-article","created":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T23:46:13Z","timestamp":1642549573000},"page":"306-313","source":"Crossref","is-referenced-by-count":7,"title":["Risk Factors for High Blood Product Use in Patients with Stanford Type A Dissection"],"prefix":"10.1055","volume":"70","author":[{"given":"Myriam","family":"Schafigh","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Heart Center, University Hospital Bonn, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armin","family":"Welz","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Heart Center, University Hospital Bonn, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marwan","family":"Hamiko","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Heart Center, University Hospital Bonn, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zaki","family":"Kohistani","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Heart Center, University Hospital Bonn, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hendrik","family":"Treede","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital Mainz, Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris","family":"Probst","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Heart Center, University Hospital Bonn, Bonn, 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