{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T07:16:57Z","timestamp":1787728617099,"version":"build-2784847793"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ultraschall in Med"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Purpose\u2002We undertook a randomized clinical trial to examine the outcome of a single vs. a double layer uterine closure using ultrasound to assess uterine scar thickness.<\/jats:p>\n                  <jats:p>Materials and Methods\u2002Participating women were allocated to one of three uterotomy suture techniques: continuous single layer unlocked suturing, continuous locked single layer suturing, or double layer suturing. Transvaginal ultrasound of\u00a0uterine scar thickness was performed 6 weeks and 6\u200a\u2013\u200a24\u00a0months after Cesarean delivery. Sonographers were blinded to the closure technique.<\/jats:p>\n                  <jats:p>Results\u2002An \u201cintent-to-treat\u201d and \u201cas treated\u201d ANOVA analysis included 435 patients (n\u200a=\u200a149 single layer unlocked suturing, n\u200a=\u200a157 single layer locked suturing, and n\u200a=\u200a129 double layer suturing). 6\u00a0weeks postpartum, the median scar thickness did\u00a0not differ among the three groups: 10.0 (8.5\u200a\u2013\u200a12.3\u200amm) single layer unlocked vs. 10.1 (8.2\u200a\u2013\u200a12.7\u200amm) single layer locked vs. 10.8 (8.1\u200a\u2013\u200a12.8\u200amm) double layer; (p\u200a=\u200a0.84). At the time of the\u00a0second follow-up, the uterine scar was not significantly (p\u200a=\u200a0.06) thicker if the uterus had been closed with a double layer closure 7.3 (5.7\u200a\u2013\u200a9.1\u200amm), compared to single layer unlocked 6.4\u00a0(5.0\u200a\u2013\u200a8.8\u200amm) or locked suturing techniques 6.8 (5.2\u200a\u2013\u200a8.7\u200amm). Women who underwent primary or elective Cesarean delivery showed a significantly (p\u200a=\u200a0.03, p\u200a=\u200a0.02, \u201cas treated\u201d) increased median scar thickness after double layer closure vs. single layer unlocked suture.<\/jats:p>\n                  <jats:p>Conclusion\u2002A double layer closure of the hysterotomy is associated with a thicker myometrium scar only in primary or elective Cesarean delivery\u00a0patients.<\/jats:p>","DOI":"10.1055\/s-0042-112223","type":"journal-article","created":{"date-parts":[[2016,9,14]],"date-time":"2016-09-14T19:09:33Z","timestamp":1473880173000},"page":"343-351","source":"Crossref","is-referenced-by-count":14,"title":["A Prospective Randomized Clinical Trial of Single vs. Double Layer Closure of Hysterotomy at the Time of Cesarean Delivery: The Effect on Uterine Scar Thickness"],"prefix":"10.1055","volume":"39","author":[{"given":"Christian","family":"Bamberg","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Charit\u00e9-University Medical Center, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joachim","family":"Dudenhausen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Charit\u00e9-University Medical Center, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verena","family":"Bujak","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Charit\u00e9-University Medical Center, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elke","family":"Rodekamp","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Charit\u00e9-University Medical Center, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Brauer","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Charit\u00e9-University Medical Center, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larry","family":"Hinkson","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Charit\u00e9-University Medical Center, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Kalache","sequence":"additional","affiliation":[{"name":"Maternal-Fetal Medicine, Obstetrics & Gynecology Department, Sidra Medical and Research Center, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Henrich","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Charit\u00e9-University Medical Center, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2016,9,14]]},"container-title":["Ultraschall in der Medizin - European Journal of Ultrasound"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0042-112223.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,6,7]],"date-time":"2018-06-07T19:12:51Z","timestamp":1528398771000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0042-112223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,14]]},"references-count":0,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2018,4,24]]},"published-print":{"date-parts":[[2018,6]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0042-112223","relation":{},"ISSN":["0172-4614","1438-8782"],"issn-type":[{"value":"0172-4614","type":"print"},{"value":"1438-8782","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,14]]}}}