{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:47:47Z","timestamp":1792133267471,"version":"4.4.0"},"reference-count":23,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"07","license":[{"start":{"date-parts":[[2022,2,9]],"date-time":"2022-02-09T00:00:00Z","timestamp":1644364800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003To review literature and estimate the occurrence of preeclampsia and its complications in Brazil.<\/jats:p><jats:p>\n          Methods\u2003We performed an integrative review of the literature, and included observational studies published until August 2021 on the SciELO and PubMed databases that evaluated preeclampsia among pregnant women in Brazil. Other variables of interests were maternal death, neonatal death, hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome, and eclampsia. Three independent reviewers evaluated all retrieved studies and selected those that met inclusion criteria. A metanalysis of the prevalence of preeclampsia and eclampsia was also performed, to estimate a pooled frequency of those conditions among the studies included.<\/jats:p><jats:p>\n          Results\u2003We retrieved 304 studies after the initial search; of those, 10 were included in the final analysis, with a total of 52,986 women considered. The pooled prevalence of preeclampsia was of 6.7%, with a total of 2,988 cases reported. The frequency of eclampsia ranged from 1.7% to 6.2%, while the occurrence of HELLP syndrome was underreported. Prematurity associated to hypertensive disorders ranged from 0.5% to 1.72%.<\/jats:p><jats:p>\n          Conclusion\u2003The frequency of preeclampsia was similar to that reported in other international studies, and it is increasing in Brazil, probably due to the adoption of new diagnostic criteria. The development of a national surveillance network would be essential to understand the problem of hypertensive disorders of pregnancy in Brazil.<\/jats:p>","DOI":"10.1055\/s-0042-1742680","type":"journal-article","created":{"date-parts":[[2022,2,9]],"date-time":"2022-02-09T23:53:28Z","timestamp":1644450808000},"page":"686-691","source":"Crossref","is-referenced-by-count":36,"title":["Prevalence of Preeclampsia in Brazil: An Integrative Review"],"prefix":"10.61622","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3648-6159","authenticated-orcid":false,"given":"Jos\u00e9 Paulo de Siqueira","family":"Guida","sequence":"additional","affiliation":[{"name":"Departament of Tocoynecology, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Estadual de Campinas, Campinas, SP, Brazil"},{"name":"Faculdade de Medicina e Odontologia e Centro de Pesquisas Odontol\u00f3gicas S\u00e3o Leopoldo Mandic, Campinas, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5628-1513","authenticated-orcid":false,"given":"Beatriz Gadioli de","family":"Andrade","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina e Odontologia e Centro de Pesquisas Odontol\u00f3gicas S\u00e3o Leopoldo Mandic, Campinas, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9046-3847","authenticated-orcid":false,"given":"Luis Gabriel Ferreira","family":"Pissinatti","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina e Odontologia e Centro de Pesquisas Odontol\u00f3gicas S\u00e3o Leopoldo Mandic, Campinas, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4858-1468","authenticated-orcid":false,"given":"Bruna Fagundes","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina e Odontologia e Centro de Pesquisas Odontol\u00f3gicas S\u00e3o Leopoldo Mandic, Campinas, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5278-1599","authenticated-orcid":false,"given":"Caio Augusto","family":"Hartman","sequence":"additional","affiliation":[{"name":"Departament of Tocoynecology, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Estadual de Campinas, Campinas, SP, Brazil"},{"name":"Faculdade de Medicina e Odontologia e Centro de Pesquisas Odontol\u00f3gicas S\u00e3o Leopoldo Mandic, Campinas, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8280-3234","authenticated-orcid":false,"given":"Maria Laura","family":"Costa","sequence":"additional","affiliation":[{"name":"Departament of Tocoynecology, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Estadual de Campinas, Campinas, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"47794","published-online":{"date-parts":[[2022,2,9]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1186\/s12884-016-1055-0","article-title":"Situational analysis of facilitators and barriers to availability and utilization of magnesium sulfate for eclampsia and severe preeclampsia in the public health system in Brazil","volume":"16","author":"F A Lotufo","year":"2016","journal-title":"BMC Pregnancy Childbirth"},{"issue":"05","key":"ref2","doi-asserted-by":"publisher","first-page":"e97401","DOI":"10.1371\/journal.pone.0097401","article-title":"The burden of eclampsia: results from a multicenter study on surveillance of severe maternal morbidity in Brazil","volume":"9","author":"J C Giordano","year":"2014","journal-title":"PLoS 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