{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T02:42:08Z","timestamp":1771036928731,"version":"3.50.1"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objectives\u2003Aortic stenosis is highly prevalent among patients with concomitant coronary artery disease. Surgical aortic valve replacement with coronary artery bypass grafting is usually the treatment of choice for patients with severe aortic stenosis and significant coronary disease. The aim of this study was to evaluate the outcome and hemodynamic results of the implantation of rapid-deployment valves (Rapid-Deployment Edwards Intuity Valve System [RDAVR]) versus conventional sutured valves (CSAVR) in combined surgery.<\/jats:p><jats:p>\n          Methods\u2003Between January 2012 and January 2017, 120 patients underwent replacement via RDAVR and 133 patients underwent replacement using CSAVR with concomitant coronary bypass grafting. Clinical and echocardiographic data were compared.<\/jats:p><jats:p>\n          Results\u2003The mean age was 76\u2009\u00b1\u20097 for RDAVR patients and 74\u2009\u00b1\u20096 years for CSAVR patients (p\u2009=\u20090.054); 48% in the RDAVR group were female versus 17% in the CSAVR group (p &lt;0.002). Other characteristics such as diabetes mellitus, body-mass index, chronic obstructive pulmonary disease, nicotine consumption, and extracardiac arteriopathy were similar. Coronary three-vessel disease was more common in the RDAVR group (42.5 vs. 27.8%, p\u2009=\u20090.017). Both mean EuroSCORE II (6.6\u2009\u00b1\u20095.4 vs. 4.3\u2009\u00b1\u20093.0, p\u2009=\u20090.001) and STS score (5.4\u2009\u00b1\u20094.4 vs. 3.4\u2009\u00b1\u20092.4, p\u2009=\u20090.001) were significantly higher in the RDAVR group. Mean cross-clamp time (82\u2009\u00b1\u200925 vs. 100\u2009\u00b1\u200930\u2009minutes, p\u2009&lt;\u20090.001) and cardiopulmonary bypass time (119\u2009\u00b1\u200938 vs. 147\u2009\u00b1\u200953\u2009minutes, p\u2009&lt;\u20090.001) were shorter with RDAVR. The mean number of bypass grafts, length of hospital and ICU stays, and mechanical ventilation time were not statistically significant different. Hospital mortality was 2.5% for RDAVR and 9.7% for CSAVR (p\u2009=\u20090.019). There was a similar rate of stroke (5.8 vs. 6.0%, p\u2009=\u20090.990) and postoperative delirium (14.1 vs. 15.8%, p\u2009=\u20090.728). Mean gradients were 8.2\u2009\u00b1\u20094.1\u2009mm Hg in the RDAVR group vs. 11.3\u2009\u00b1\u20094.6\u2009mm Hg in the CSAVR group (p\u2009=\u20090.001) at discharge.<\/jats:p><jats:p>\n          Conclusion\u2003RDAVR combined with coronary artery bypass grafting (CABG) can be performed extremely safely. Cross-clamp and cardiopulmonary bypass times can be significantly reduced with rapid deployment aortic valve system in the scenario of combined CABG. RDAVR resulted in lower gradients than CSAVR in patients implanted with prostheses of the same size.<\/jats:p>","DOI":"10.1055\/s-0042-1742686","type":"journal-article","created":{"date-parts":[[2022,2,12]],"date-time":"2022-02-12T23:36:06Z","timestamp":1644708966000},"page":"519-527","source":"Crossref","is-referenced-by-count":5,"title":["Early-Term Results of Rapid-Deployment Aortic Valve Replacement versus Standard Bioprosthesis Implantation Combined with Coronary Artery Bypass Grafting"],"prefix":"10.1055","volume":"71","author":[{"given":"Zulfugar T.","family":"Taghiyev","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic SurgeryRuhr-University Hospital Bergmannsheil, Bochum, Germany"},{"name":"Department of Adult and Pediatric Cardiovascular Surgery, University Hospital of Giessen and Marburg, Giessen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Bechtel","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic SurgeryRuhr-University Hospital Bergmannsheil, Bochum, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Schl\u00f6micher","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic SurgeryRuhr-University Hospital Bergmannsheil, Bochum, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8312-330X","authenticated-orcid":false,"given":"Dritan","family":"Useini","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic SurgeryRuhr-University Hospital Bergmannsheil, Bochum, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamid Naraghi","family":"Taghi","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic SurgeryRuhr-University Hospital Bergmannsheil, Bochum, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vadim","family":"Moustafine","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic SurgeryRuhr-University Hospital Bergmannsheil, Bochum, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justus T.","family":"Strauch","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic SurgeryRuhr-University Hospital Bergmannsheil, Bochum, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,2,12]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0140-6736(06)69208-8","article-title":"Burden of valvular heart diseases: a population-based study","volume":"368","author":"V T 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