{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T20:37:35Z","timestamp":1779395855274,"version":"3.53.1"},"reference-count":32,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T00:00:00Z","timestamp":1651449600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Dent"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objectives\u2003The objective of our study was to assess the current knowledge, the oral health status, and the pro-health needs of patients with hemophilia.<\/jats:p><jats:p>\n          Materials and Methods\u2003The study included 77 patients with known hemophilia. The study included the assessment of dental indicators related to caries incidence (decayed, missing, and filled teeth [DMFT] and decayed, missing, and filled permanent teeth or surfaces [DMFS]), caries treatment (treatment index), oral hygiene status (Approximal Plaque Index [API] and simplified oral hygiene index [OHI-S]), and periodontal status (bleeding on probing [BoP]). A questionnaire addressed symptoms of hemorrhagic diathesis and health-promoting habits. The influence of routine management (\u201con-demand\u201d vs. prophylactic therapy), type of hemophilia (A, B), and severity of clotting factor deficiency (mild, moderate, or severe) on oral health was assessed.<\/jats:p><jats:p>\n          Statistical Analysis\u2003The tests used in the study were Shapiro\u2013Wilk, Mann\u2013Whitney, Kruskal\u2013Wallis, and Dunn's tests. The level of significance was set at p\u2009&lt;\u20090.05.<\/jats:p><jats:p>\n          Results\u2003Patients with hemophilia showed a higher prevalence of caries compared with patients without hemorrhagic diathesis (DMFT 14 and 9, and DMFS 30 and 15, respectively), and they also presented a higher bleeding index value during probing and worse effectiveness of hygienic interdental procedures. The type of therapy and secondary prophylaxis used and the type and severity of hemophilia did not affect the oral health status.<\/jats:p><jats:p>\n          Conclusions\u2003Patients with hemophilia have an increased risk of developing dental caries. Undertaking educational activities related to the prevention of oral diseases is necessary to improve oral health.<\/jats:p>","DOI":"10.1055\/s-0042-1743156","type":"journal-article","created":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T23:04:07Z","timestamp":1651532647000},"page":"161-172","source":"Crossref","is-referenced-by-count":11,"title":["Assessment of Oral Health and Healthy Habits in Adult Patients with Congenital Hemophilia"],"prefix":"10.1055","volume":"17","author":[{"given":"Sylwia","family":"Czajkowska","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Poznan University of Medical Sciences, Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Rupa-Matysek","sequence":"additional","affiliation":[{"name":"Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidia","family":"Gil","sequence":"additional","affiliation":[{"name":"Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9952-0230","authenticated-orcid":false,"given":"Anna","family":"Surdacka","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Poznan University of Medical Sciences, Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,5,2]]},"reference":[{"key":"ref2","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1016\/S0049-3848(16)30354-1","article-title":"The hemostatic role of factor XI","volume":"141","author":"C Puy","year":"2016","journal-title":"Thromb 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