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However, deep cartilage layers, intrachondral composition, and the subchondral bone are only partially or not at all visualized with arthroscopy. In contrast, magnetic resonance imaging offers noninvasive evaluation of the cartilage repair site, the subchondral bone, and the soft tissues of the joint pre- and postsurgery. Radiologists need to be familiar with the different surgical procedures available and their characteristic postsurgical imaging appearances to assess treatment success and possible complications adequately. We provide an overview of the most commonly performed surgical procedures for cartilage repair at the knee and typical postsurgical imaging characteristics.<\/jats:p>","DOI":"10.1055\/s-0042-1743405","type":"journal-article","created":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T19:07:08Z","timestamp":1654196828000},"page":"216-229","source":"Crossref","is-referenced-by-count":2,"title":["Update: Posttreatment Imaging of the Knee after Cartilage Repair"],"prefix":"10.1055","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2897-5411","authenticated-orcid":false,"given":"Rafael","family":"Heiss","sequence":"additional","affiliation":[{"name":"Department of Radiology, Universityhospital Erlangen, Friedrich-Alexander University Erlangen-N\u00fcrnberg (FAU), Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Guermazi","sequence":"additional","affiliation":[{"name":"Department of Radiology, VA Healthcare System, West Roxbury, Massachusetts"},{"name":"Department of Radiology, Boston University School of Medicine, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rolf","family":"Janka","sequence":"additional","affiliation":[{"name":"Department of Radiology, Universityhospital Erlangen, Friedrich-Alexander University Erlangen-N\u00fcrnberg (FAU), Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Uder","sequence":"additional","affiliation":[{"name":"Department of Radiology, Universityhospital Erlangen, Friedrich-Alexander University Erlangen-N\u00fcrnberg (FAU), Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinning","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Boston University School of Medicine, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daichi","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Stony Brook University Renaissance School of Medicine, Stony Brook, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank W.","family":"Roemer","sequence":"additional","affiliation":[{"name":"Department of Radiology, Universityhospital Erlangen, Friedrich-Alexander University Erlangen-N\u00fcrnberg (FAU), Erlangen, Germany"},{"name":"Department of Radiology, Boston University School of Medicine, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,6,2]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/S0749-8063(97)90124-9","article-title":"Cartilage injuries: a review of 31,516 knee arthroscopies","volume":"13","author":"W W 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Guermazi","year":"2015","journal-title":"Radiology"},{"issue":"01","key":"ref5","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1177\/0363546503259345","article-title":"Articular cartilage lesions in 993 consecutive knee arthroscopies","volume":"32","author":"A Ar\u00f8en","year":"2004","journal-title":"Am J Sports Med"},{"issue":"07","key":"ref6","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1053\/jars.2002.32839","article-title":"Articular cartilage defects in 1,000 knee arthroscopies","volume":"18","author":"K Hjelle","year":"2002","journal-title":"Arthroscopy"},{"issue":"S 01","key":"ref7","doi-asserted-by":"crossref","first-page":"167S","DOI":"10.1177\/0363546509351650","article-title":"Return to sports participation after articular cartilage repair in the knee: scientific evidence","volume":"37","author":"K Mithoefer","year":"2009","journal-title":"Am J Sports 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Schneider","year":"2008","journal-title":"Osteoarthritis Cartilage"},{"issue":"04","key":"ref38","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s00256-012-1511-5","article-title":"Magnetic resonance transverse relaxation time T2 of knee cartilage in osteoarthritis at 3-T: a cross-sectional multicentre, multivendor reproducibility study","volume":"42","author":"S Balamoody","year":"2013","journal-title":"Skeletal Radiol"},{"issue":"12","key":"ref39","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1016\/j.joca.2017.08.007","article-title":"Editorial: from theory to practice\u2014the challenges of compositional MRI in osteoarthritis research","volume":"25","author":"F W Roemer","year":"2017","journal-title":"Osteoarthritis Cartilage"},{"issue":"03","key":"ref40","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1002\/mrm.22469","article-title":"Influence of knee positions on T2, T*2, and dGEMRIC mapping in porcine knee cartilage","volume":"64","author":"T Shiomi","year":"2010","journal-title":"Magn Reson Med"},{"issue":"10","key":"ref41","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1007\/s00256-014-1852-3","article-title":"T2* mapping for articular cartilage assessment: principles, current applications, and future prospects","volume":"43","author":"T Hesper","year":"2014","journal-title":"Skeletal Radiol"},{"issue":"03","key":"ref42","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s00256-011-1171-x","article-title":"T2 star relaxation times for assessment of articular cartilage at 3 T: a feasibility study","volume":"41","author":"T C Mamisch","year":"2012","journal-title":"Skeletal Radiol"},{"issue":"06","key":"ref43","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1002\/jmri.23598","article-title":"T2* measurement of the knee articular cartilage in osteoarthritis at 3T","volume":"35","author":"R D Newbould","year":"2012","journal-title":"J Magn Reson 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model","volume":"282","author":"Y Kang","year":"2017","journal-title":"Radiology"},{"issue":"01","key":"ref47","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1002\/jmri.26816","article-title":"Feasibility of using half-dose Gd-BOPTA for delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) at the knee, compared with standard-dose Gd-DTPA","volume":"51","author":"C Rehnitz","year":"2020","journal-title":"J Magn Reson Imaging"},{"issue":"06","key":"ref48","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1007\/s00330-008-0859-3","article-title":"Differentiating normal hyaline cartilage from post-surgical repair tissue using fast gradient echo imaging in delayed gadolinium-enhanced MRI (dGEMRIC) at 3 Tesla","volume":"18","author":"S Trattnig","year":"2008","journal-title":"Eur Radiol"},{"issue":"04","key":"ref49","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.joca.2006.10.001","article-title":"Evaluation of cartilage repair in the distal femur after 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Trattnig","year":"2010","journal-title":"Radiology"},{"issue":"05","key":"ref55","first-page":"422","article-title":"Advanced cartilage imaging for detection of cartilage injuries and osteochondral lesions. [in German]","volume":"58","author":"A S Gersing","year":"2018","journal-title":"Radiologe"},{"issue":"07","key":"ref56","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.joca.2012.03.007","article-title":"CT arthrography of the human knee to measure cartilage quality with low radiation dose","volume":"20","author":"J van Tiel","year":"2012","journal-title":"Osteoarthritis Cartilage"},{"issue":"01","key":"ref57","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/1947603509360209","article-title":"Magnetic resonance imaging of cartilage repair: a review","volume":"2","author":"S Trattnig","year":"2011","journal-title":"Cartilage"},{"issue":"04","key":"ref58","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1055\/s-2001-19044","article-title":"Postoperative magnetic resonance imaging of articular cartilage repair","volume":"5","author":"L Alparslan","year":"2001","journal-title":"Semin Musculoskelet Radiol"},{"issue":"04","key":"ref59","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1148\/rg.284075111","article-title":"MR imaging of cartilage repair in the knee and ankle","volume":"28","author":"Y S Choi","year":"2008","journal-title":"Radiographics"},{"issue":"01","key":"ref60","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1007\/s00330-005-2818-6","article-title":"Normal and pathological MR findings in osteochondral autografts with longitudinal follow-up","volume":"16","author":"T M Link","year":"2006","journal-title":"Eur Radiol"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"571S","DOI":"10.1177\/1947603519865308","article-title":"The MOCART (Magnetic Resonance Observation of Cartilage Repair Tissue) 2.0 Knee Score and Atlas","volume":"13","author":"M M Schreiner","year":"2021","journal-title":"Cartilage"},{"issue":"06","key":"ref62","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.joca.2014.03.014","article-title":"Whole joint MRI assessment of surgical cartilage repair of the knee: cartilage repair osteoarthritis knee score (CROAKS)","volume":"22","author":"F W Roemer","year":"2014","journal-title":"Osteoarthritis Cartilage"},{"issue":"03","key":"ref63","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1177\/1941738113508917","article-title":"Current concepts of articular cartilage restoration techniques in the knee","volume":"6","author":"C L Camp","year":"2014","journal-title":"Sports Health"},{"issue":"18","key":"ref64","doi-asserted-by":"crossref","first-page":"e137","DOI":"10.2106\/JBJS.M.00381","article-title":"Augmented microfracture: Is this the Holy Grail that we have been searching for in the treatment of cartilage injuries?: Commentary on an article by William D. 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