{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T22:52:45Z","timestamp":1772751165161,"version":"3.50.1"},"reference-count":80,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":87,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Radiol Imaging"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Pulmonary infections are the major cause of morbidity and mortality in immunocompromised patients and almost one-third of intensive care unit patients with pulmonary infections belong to the immunocompromised category. Multiple organisms may simultaneously infect an immunocompromised patient and the overwhelming burden of mixed infections further predisposes critically ill patients to acute hypoxemic respiratory failure. Notwithstanding that lung ultrasound is coming into vogue, the primary imaging investigation is a chest radiograph, followed by thoracic CT scan. This review based on our experience at tertiary care teaching hospitals provides insights into the spectrum of imaging features of various pulmonary infections occurring in immunocompromised patients. This review is unique as, firstly, the imaging spectrum described by us is categorized on basis of the etiological infective agent, comprehensively and emphatically correlated with the clinical setting of the patient. Secondly, a characteristic imaging pattern is emphasized in the clinical setting-imaging-pattern conglomerate, to highlight the most likely diagnosis possible in such a combination. Thirdly, the simulating conditions for a relevant differential diagnosis are discussed in each section. Fourthly, not only are the specific diagnostic and tissue sampling techniques for confirmation of the suspected etiological agent described, but the recommended pharmaco-therapeutic agents are also enumerated, so as to provide a more robust insight to the radiologist. Last but not the least, we summarize and conclude with a diagnostic algorithm, derived by us from the characteristic illustrative cases. The proposed algorithm, illustrated as a flowchart, emphasizes a diagnostic imaging approach comprising: correlation of the imaging pattern with clinical setting and with associated abnormalities in the thorax and in other organs\/systems, which is comprehensively analyzed in arriving at the most likely diagnosis. Since a rapid evaluation and emergent management of such patients is of pressing concern not only to the radiologist, but also for the general physicians, pulmonologists, critical care specialists, oncologists and transplant surgery teams, we believe our review is very informative to a wide spectrum reader audience.<\/jats:p>","DOI":"10.1055\/s-0042-1743418","type":"journal-article","created":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T23:34:56Z","timestamp":1653694496000},"page":"081-112","source":"Crossref","is-referenced-by-count":11,"title":["Imaging Approach to Pulmonary Infections in the Immunocompromised Patient"],"prefix":"10.1055","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7691-494X","authenticated-orcid":false,"given":"Shabnam Bhandari","family":"Grover","sequence":"additional","affiliation":[{"name":"Department of Radiology, VMMC and Safdarjung Hospital, New Delhi (Former and source of this work)"},{"name":"Department of Radiology and Imaging, Sharda School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India (Current)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hemal","family":"Grover","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging, Icahn School of Medicine at Mount Sinai West, New York, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neha","family":"Antil","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging, Stanford University, California, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayantan","family":"Patra","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manas Kamal","family":"Sen","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepthi","family":"Nair","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,5,27]]},"reference":[{"issue":"05","key":"ref1","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1097\/RTI.0000000000000351","article-title":"Pulmonary infections in immunocompromised hosts: Clinical","volume":"33","author":"C Vazquez Guillamet","year":"2018","journal-title":"J Thorac Imaging"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1148\/radiology.217.3.r00dc35647","article-title":"Pulmonary infections in immunocompromised hosts: the importance of correlating the conventional radiologic 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