{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:27:40Z","timestamp":1787164060845,"version":"build-2736575974"},"reference-count":32,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr Surg"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Introduction\u2003Prenatal ultrasound-guided laser coagulation (USLC) for complicated bronchopulmonary sequestrations has been described but a consensus on the procedure and on the following management is still lacking. We present our experience and provide a literature review.<\/jats:p>\n                  <jats:p>Methods\u2003Retrospective review of patients treated in our center. Literature review and combined analysis of perinatal data were performed.<\/jats:p>\n                  <jats:p>Results\u2003Five cases were treated at our center, all presenting with severe hydrothorax. Four met the criteria for fetal hydrops. Four cases underwent postnatal computed tomography (CT) scan: in one case, there was no evidence of persistent bronchopulmonary sequestration. The other three underwent thoracoscopic resection, in two, a viable sequestration was found. Including our series, 57 cases have been reported, with no mortality and a success rate of 94.7%. Mean gestational age (GA) at the procedure was 28\u2009\u00b1\u20093.4 weeks and mean GA at birth and birth weight (BW) were 38.6\u2009\u00b1\u20092.3 weeks and 3,276\u2009\u00b1\u2009519.8\u2009g, respectively. In 80.6% of the cases investigated postnatally, a residual mass was found, 50% of cases who showed prenatal arterial flow cessation had a persistent sequestration postnatally, and 26.3% of cases underwent postnatal sequestrectomy. Both patients in our series had pathology examination confirming a viable bronchopulmonary sequestration.<\/jats:p>\n                  <jats:p>Conclusion\u2003Prenatal USLC seems to be a valid option for bronchopulmonary sequestration complicated by severe hydrothorax and\/or fetal hydrops. Authors believe that this procedure should aim to reverse fetal distress and allow pregnancy continuation, and it should not be considered a definitive treatment. The currently available data do not support changes of the common postnatal management.<\/jats:p>","DOI":"10.1055\/s-0042-1744149","type":"journal-article","created":{"date-parts":[[2022,3,14]],"date-time":"2022-03-14T20:00:24Z","timestamp":1647288024000},"page":"536-542","source":"Crossref","is-referenced-by-count":7,"title":["Intrauterine Ultrasound-Guided Laser Coagulation as a First Step for Treatment of Prenatally Complicated Bronchopulmonary Sequestration: Our Experience and Literature Review"],"prefix":"10.1055","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6857-0518","authenticated-orcid":false,"given":"Andrea","family":"Zanini","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Macchini","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Boito","sequence":"additional","affiliation":[{"name":"Department of Fetal Medicine and Surgery Service, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Morandi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuditta","family":"Ferrara","sequence":"additional","affiliation":[{"name":"Department of Fetal Medicine and Surgery Service, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Persico","sequence":"additional","affiliation":[{"name":"Department of Fetal Medicine and Surgery Service, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardia, Italy"},{"name":"Department of Clinical Sciences and Community Health, University of Milan, Milano, Lombardia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernesto","family":"Leva","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardia, Italy"},{"name":"Department of Clinical Sciences and Community Health, University of Milan, Milano, Lombardia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,3,14]]},"reference":[{"issue":"02","key":"ref1","first-page":"103","article-title":"Fetal thoracic lesions","volume":"2","author":"N S 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