{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T18:08:28Z","timestamp":1785175708694,"version":"3.55.0"},"reference-count":7,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T00:00:00Z","timestamp":1656547200000},"content-version":"vor","delay-in-days":29,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Radiol Imaging"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report magnetic resonance imaging (MRI) in a case with otosyphilis, which is a rare manifestation of neurosyphilis. A 50-year-old male presented with progressive hearing loss on the left side and recent-onset palsy of the left 7th and 12th cranial nerves. Computed tomography imaging showed destructive bone lesions involving the petrous temporal bone, middle ear, and mastoid region with a pathognomonic pattern of bone destruction depicted in the volume rendering technique images. MRI showed features of destructive bone lesions (gummatous lesion), meningoneuritis, and labyrinthitis. Pathological examination and treponemal antibody absorption test favored the diagnosis. Otosyphilis should be considered as a differential diagnosis in an adult patient with destructive lesions of the petrous temporal bone. To the best of our knowledge, MRI in otosyphilis has not been reported.<\/jats:p>","DOI":"10.1055\/s-0042-1744523","type":"journal-article","created":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T23:30:17Z","timestamp":1656631817000},"page":"278-284","source":"Crossref","is-referenced-by-count":5,"title":["Magnetic Resonance Imaging in Otosyphilis: A Rare Manifestation of Neurosyphilis"],"prefix":"10.1055","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1509-7007","authenticated-orcid":false,"given":"Rajsekar","family":"Chandrasekharan","sequence":"additional","affiliation":[{"name":"Department of Radiology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chinmay","family":"Kulkarni","sequence":"additional","affiliation":[{"name":"Department of Radiology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreekumar Karumathil","family":"Pullara","sequence":"additional","affiliation":[{"name":"Department of Radiology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8587-7930","authenticated-orcid":false,"given":"Srikanth","family":"Moorthy","sequence":"additional","affiliation":[{"name":"Department of Radiology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,6,30]]},"reference":[{"issue":"04","key":"ref2","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jrid.2015.11.006","article-title":"MRI of neurosyphilis presenting as brain tumor: A case report","volume":"2","author":"M Chu","year":"2015","journal-title":"Radiol Infect Dis"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1086\/318719","article-title":"An unusual manifestation of acquired syphilis","volume":"32","author":"I A Gurland","year":"2001","journal-title":"Clin Infect Dis"},{"issue":"07","key":"ref4","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1148\/rg.287085135","article-title":"From the archives of the AFIP: central nervous system infections associated with human immunodeficiency virus infection: radiologic-pathologic correlation","volume":"28","author":"A B Smith","year":"2008","journal-title":"Radiographics"},{"issue":"04","key":"ref5","first-page":"332","article-title":"Lesions of the skull in secondary syphilis","volume":"36","author":"R G Thompson","year":"1952","journal-title":"Am J Syph Gonorrhea Vener Dis"},{"issue":"04","key":"ref6","first-page":"703","article-title":"Neurosyphilis in HIV-positive and HIV-negative patients: neuroimaging findings","volume":"16","author":"T C Brightbill","year":"1995","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1097\/00129492-200209000-00033","article-title":"Manifestations of otosyphilis as visualized with computed tomography","volume":"23","author":"J E Sonne","year":"2002","journal-title":"Otol Neurotol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1017\/S0022215113003575","article-title":"Computed tomography features of luetic osteitis (otosyphilis) of the temporal bone","volume":"128","author":"A Ogungbemi","year":"2014","journal-title":"J Laryngol Otol"}],"container-title":["Indian Journal of Radiology and Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0042-1744523.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T08:45:18Z","timestamp":1717749918000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0042-1744523"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":7,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2022,7,30]]},"published-print":{"date-parts":[[2022,6]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0042-1744523","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0971-3026","1998-3808"],"issn-type":[{"value":"0971-3026","type":"print"},{"value":"1998-3808","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6]]}}}