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While a variety of tools and techniques are available for the management of malignant obstructive lesions, advancements and evolution in this therapeutic venue have been somewhat sluggish and limited when compared with other branches of interventional pulmonary medicine (e.g., the early diagnosis of peripheral lung nodules). Indeed, one pragmatic, albeit somewhat uncharitable, reading of this article's title might suggest a wry smile and shug of the shoulders as to imply that relatively little has changed in recent years. That said, the spectrum of interventions for MCAO continues to expand, even if at a less impressive clip. Herein, we present on MCAO and its endoscopic and nonendoscopic management-that which is old, that which is new, and that which is still on the horizon.<\/jats:p>","DOI":"10.1055\/s-0042-1748187","type":"journal-article","created":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T23:32:55Z","timestamp":1654212775000},"page":"512-529","source":"Crossref","is-referenced-by-count":5,"title":["Malignant Central Airway Obstruction: What's New?"],"prefix":"10.1055","volume":"43","author":[{"given":"Brian D.","family":"Shaller","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Allergy and Critical Care Medicine, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darius","family":"Filsoof","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Allergy and Critical Care Medicine, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge M.","family":"Pineda","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Allergy and Critical Care Medicine, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas R.","family":"Gildea","sequence":"additional","affiliation":[{"name":"Respiratory Institute, Cleveland Clinic, Cleveland, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,6,2]]},"reference":[{"issue":"12","key":"ref1","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1164\/rccm.200210-1181SO","article-title":"Central airway obstruction","volume":"169","author":"A Ernst","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"issue":"05","key":"ref2","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1378\/chest.14-1526","article-title":"Therapeutic bronchoscopy 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