{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:15:09Z","timestamp":1787004909904,"version":"build-2736575974"},"reference-count":40,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg A Cent Eur Neurosurg"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background and Study Aims\u2003Spinal instrumentation for spondylodiskitis (SD) remains highly controversial. To date, surgical data are limited to relatively small case series with short-term follow-up data. In this study, we wanted to elucidate the biomechanical, surgical, and neurologic long-term outcomes in these patients.<\/jats:p>\n                  <jats:p>Material and Methods\u2003A retrospective analysis from two German primary care hospitals over a 9-year period (2005\u20132014) was performed. The inclusion criteria were (1) pyogenic lumbar SD, (2) minimum follow-up of 1 year, and (3) surgical instrumentation. The clinical and radiologic outcome was assessed before surgery, at discharge, and at a minimum of 12 months of follow-up. Follow-up included physical examination, laboratory results, CT and MRI scans, as well as assessment of quality of life (QoL) using short-form health survey (SF-36) inventory, Oswestry Disability Questionnaire, and visual analog scale (VAS) spine score.<\/jats:p>\n                  <jats:p>Results\u2003Complete data were available in 70 patients (49 males and 21 females, with an age range of 67\u00b112.3 years) with a median follow-up of 6.6\u2009\u00b1\u20094.2 years. Follow-up data were available in 70 patients after 1 year, in 58 patients after 2 years, and in 44 patients after 6 years. Thirty-five patients underwent posterior stabilization and decompression alone and 35 patients were operated on in a two-stage 360-degree interbody fusion with decompression. Pre- and postoperative angles of the affected motion segment were 17.6\u2009\u00b1\u200910.2 and 16.1\u2009\u00b1\u200910.7 degrees in patients with posterior instrumentation only and 21.0\u2009\u00b1\u200910.2 and 18.3\u2009\u00b1\u200910.5 degrees in patients with combined anterior\/posterior fusion. Vertebral body subsidence was seen in 12 and 6 cases following posterior instrumentation and 360-degree instrumentation, respectively. Nonfusion was encountered in 22 and 11 cases following posterior instrumentation and 360-degree instrumentation, respectively. The length of hospital stay was 35.0\u2009\u00b1\u200924.5 days. Surgery-associated complication rate was 18% (12\/70). New neurologic symptoms occurred in 7% (5\/70). Revision surgery was performed in 3% (2\/70) due to screw misplacement\/hardware failure and in 3% (2\/70) due to intraspinal hematoma. Although patients reported a highly impaired pain deception and vitality, physical mobility was unaffected and pain disability during daily activities was moderate.<\/jats:p>\n                  <jats:p>Conclusion\u2003Surgical treatment of SD with a staged surgical approach (if needed) is safe and provides very good long-term clinical and radiologic outcome.<\/jats:p>","DOI":"10.1055\/s-0042-1748767","type":"journal-article","created":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T19:15:17Z","timestamp":1656357317000},"page":"44-51","source":"Crossref","is-referenced-by-count":4,"title":["Long-Term Clinical and Radiologic Outcome Following Surgical Treatment of Lumbar Spondylodiscitis: A Retrospective Bicenter Study"],"prefix":"10.1055","volume":"84","author":[{"given":"Bj\u00f6rn","family":"Sommer","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospital Erlangen, Erlangen, Germany"},{"name":"Department of Neurosurgery, University Hospital Augsburg, Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo","family":"Babbe-Pekol","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospital Erlangen, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Feulner","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospital Erlangen, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard Heinrich","family":"Richter","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Malteser Waldkrankenhaus St. Marien, University Hospital Erlangen, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Buchfelder","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospital Erlangen, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehab","family":"Shiban","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospital Augsburg, Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Sesselmann","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Malteser Waldkrankenhaus St. Marien, University Hospital Erlangen, Erlangen, Germany"},{"name":"Institute for Medical Engineering, OTH Technical University of Applied Sciences Amberg-Weiden, Amberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raimund","family":"Forst","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Malteser Waldkrankenhaus St. Marien, University Hospital Erlangen, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurt","family":"Wiendieck","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospital Erlangen, Erlangen, Germany"},{"name":"Department of Spine Surgery, Kliniken Dr. Erler GmbH, N\u00fcrnberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,6,27]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s00264-011-1441-1","article-title":"Surgical treatment of spondylodiscitis. 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