{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T01:53:56Z","timestamp":1769306036911,"version":"3.49.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hand and Microsurgery"],"published-print":{"date-parts":[[2023]]},"DOI":"10.1055\/s-0042-1748783","type":"journal-article","created":{"date-parts":[[2022,8,27]],"date-time":"2022-08-27T18:34:23Z","timestamp":1661625263000},"page":"106-115","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Multifactorial Analysis of Treatment of Long-Bone Nonunion with Vascularized and Nonvascularized Bone Grafts"],"prefix":"10.1016","volume":"15","author":[{"given":"Marco","family":"Guidi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4924-5549","authenticated-orcid":false,"given":"Matteo","family":"Guzzini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Civitenga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riccardo Maria","family":"Lanzetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bong-Sung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3821-7163","authenticated-orcid":false,"given":"Inga Swantje","family":"Besmens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Riegger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Lucchina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4372-0561","authenticated-orcid":false,"given":"Maurizio","family":"Calcagni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dario","family":"Perugia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1055\/s-0042-1748783_bib001","first-page":"694","article-title":"The autogenous bone graft","volume":"21","author":"Campbell","year":"1939","journal-title":"J Bone Joint Surg"},{"issue":"05","key":"10.1055\/s-0042-1748783_bib002","doi-asserted-by":"crossref","first-page":"716","DOI":"10.2106\/00004623-200205000-00003","article-title":"Comparison of anterior and posterior iliac crest bone grafts in terms of harvest-site morbidity and functional outcomes","volume":"84","author":"Ahlmann","year":"2002","journal-title":"J Bone Joint Surg Am"},{"issue":"02","key":"10.1055\/s-0042-1748783_bib003","doi-asserted-by":"crossref","first-page":"181","DOI":"10.2106\/00004623-198466020-00004","article-title":"The efficacy of free tissue transfer in the treatment of osteomyelitis","volume":"66","author":"Weiland","year":"1984","journal-title":"J Bone Joint Surg Am"},{"issue":"01","key":"10.1055\/s-0042-1748783_bib004","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/(SICI)1097-0347(199901)21:1<66::AID-HED9>3.0.CO;2-Z","article-title":"Vascularized bone flaps versus nonvascularized bone grafts for mandibular reconstruction: an outcome analysis of primary bony union and endosseous implant success","volume":"21","author":"Foster","year":"1999","journal-title":"Head Neck"},{"issue":"01","key":"10.1055\/s-0042-1748783_bib005","doi-asserted-by":"crossref","first-page":"S70","DOI":"10.1016\/S0020-1383(13)70016-0","article-title":"Vascularized bone grafts for the management of skeletal defects in orthopaedic trauma and reconstructive surgery","volume":"44","author":"Soucacos","year":"2013","journal-title":"Injury"},{"issue":"04","key":"10.1055\/s-0042-1748783_bib006","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1055\/s-2007-1006709","article-title":"Reconstruction of the bones and joints of the upper extremity by vascularized free fibular graft: report of 46 cases","volume":"8","author":"Tang","year":"1992","journal-title":"J Reconstr Microsurg"},{"issue":"03","key":"10.1055\/s-0042-1748783_bib007","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/micr.20841","article-title":"Vascularized fibula transfer for lower limb reconstruction","volume":"31","author":"Beris","year":"2011","journal-title":"Microsurgery"},{"issue":"05","key":"10.1055\/s-0042-1748783_bib008","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1097\/00006534-197505000-00002","article-title":"The free vascularized bone graft. A clinical extension of microvascular techniques","volume":"55","author":"Taylor","year":"1975","journal-title":"Plast Reconstr Surg"},{"issue":"419","key":"10.1055\/s-0042-1748783_bib009","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1097\/00003086-200402000-00007","article-title":"Free vascularized fibular grafts have a high union rate in atrophic nonunions","author":"Gonz\u00e1lez del Pino","year":"2004","journal-title":"Clin Orthop Relat Res"},{"issue":"05","key":"10.1055\/s-0042-1748783_bib0010","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1002\/micr.1920150505","article-title":"Vascularized periosteal bone graft from the supracondylar region of the femur","volume":"15","author":"Doi","year":"1994","journal-title":"Microsurgery"},{"issue":"05","key":"10.1055\/s-0042-1748783_bib0011","doi-asserted-by":"crossref","first-page":"S54","DOI":"10.1016\/j.injury.2019.10.049","article-title":"The medial femoral condyle free corticoperiosteal flap versus traditional bone graft for treatment of nonunions of long bones: a retrospective comparative cohort study","volume":"50","author":"Ciclamini","year":"2019","journal-title":"Injury"},{"issue":"05","key":"10.1055\/s-0042-1748783_bib0012","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1007\/s11999-016-4769-4","article-title":"Vascularized versus nonvascularized bone grafts: what is the evidence?","volume":"474","author":"Allsopp","year":"2016","journal-title":"Clin Orthop Relat Res"},{"key":"10.1055\/s-0042-1748783_bib0013","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1214\/08-AOAS191","article-title":"A weakly informative default prior distribution for logistic and other regression models","volume":"2","author":"Gelman","year":"2008","journal-title":"Ann Appl Stat"},{"key":"10.1055\/s-0042-1748783_bib0014","doi-asserted-by":"crossref","unstructured":"AC Davison DV Hinkley Bootstrap Methods and Their Application. Vol. 1 Cambridge, UK: Cambridge University Press 1997.","DOI":"10.1017\/CBO9780511802843"},{"issue":"03","key":"10.1055\/s-0042-1748783_bib0015","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1097\/00006534-198609000-00001","article-title":"Early microsurgical reconstruction of complex trauma of the extremities","volume":"78","author":"Godina","year":"1986","journal-title":"Plast Reconstr Surg"},{"issue":"06","key":"10.1055\/s-0042-1748783_bib0016","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1097\/01.PRS.0000138811.88807.65","article-title":"One-stage reconstruction of composite bone and soft-tissue defects in traumatic lower extremities","volume":"114","author":"Yazar","year":"2004","journal-title":"Plast Reconstr Surg"},{"issue":"06","key":"10.1055\/s-0042-1748783_bib0017","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1007\/s00264-014-2281-6","article-title":"Free vascularised fibular grafts in orthopaedics","volume":"38","author":"Bumbasirevic","year":"2014","journal-title":"Int Orthop"},{"issue":"04","key":"10.1055\/s-0042-1748783_bib0018","first-page":"436","article-title":"Osseous union in cases of non-union in long bones treated by osteosynthesis","volume":"13","author":"Nwagbara","year":"2010","journal-title":"Niger J Clin Pract"},{"issue":"03","key":"10.1055\/s-0042-1748783_bib0019","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.jse.2004.06.007","article-title":"Free vascularized corticoperiosteal bone graft for the treatment of persistent nonunion of the clavicle","volume":"14","author":"Fuchs","year":"2005","journal-title":"J Shoulder Elbow Surg"},{"issue":"03","key":"10.1055\/s-0042-1748783_bib0020","doi-asserted-by":"crossref","first-page":"S66","DOI":"10.1016\/S0020-1383(17)30661-7","article-title":"The treatment of long bones nonunions of upper limb with microsurgical cortico-periosteal free flap","volume":"48","author":"Guzzini","year":"2017","journal-title":"Injury"},{"issue":"02","key":"10.1055\/s-0042-1748783_bib0021","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1097\/SAP.0b013e318056d6b5","article-title":"The vascularized medial femoral condyle periosteal bone flap for the treatment of recalcitrant bony nonunions","volume":"60","author":"Choudry","year":"2008","journal-title":"Ann Plast Surg"},{"issue":"01","key":"10.1055\/s-0042-1748783_bib0022","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1080\/00016470310013734","article-title":"Recalcitrant posttraumatic nonunion of the humerus: 23 patients reconstructed with vascularized bone graft","volume":"74","author":"Muramatsu","year":"2003","journal-title":"Acta Orthop Scand"},{"issue":"10","key":"10.1055\/s-0042-1748783_bib0023","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.2106\/00004623-199274100-00002","article-title":"Vascularized bone transfer","volume":"74","author":"Han","year":"1992","journal-title":"J Bone Joint Surg Am"},{"issue":"06","key":"10.1055\/s-0042-1748783_bib0024","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1302\/2046-3758.26.2000142","article-title":"The effect of smoking on bone healing: a systematic review","volume":"2","author":"Patel","year":"2013","journal-title":"Bone Joint Res"},{"issue":"09","key":"10.1055\/s-0042-1748783_bib0025","first-page":"590","article-title":"Cigarette smoking and its orthopedic consequences","volume":"25","author":"Kwiatkowski","year":"1996","journal-title":"Am J Orthop"},{"issue":"11","key":"10.1055\/s-0042-1748783_bib0026","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.3113\/FAI.2009.1042","article-title":"Early complications following the operative treatment of pilon fractures with and without diabetes","volume":"30","author":"Kline","year":"2009","journal-title":"Foot Ankle Int"},{"issue":"02","key":"10.1055\/s-0042-1748783_bib0027","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/S0020-1383(79)80011-X","article-title":"Open fractures of the shaft of the tibia: analysis of wound and fracture treatment","volume":"11","author":"Widenfalk","year":"1979","journal-title":"Injury"},{"issue":"05","key":"10.1055\/s-0042-1748783_bib0028","doi-asserted-by":"crossref","first-page":"S36","DOI":"10.1097\/BOT.0000000000000979","article-title":"Induced membrane technique: pearls and pitfalls","volume":"31","author":"Masquelet","year":"2017","journal-title":"J Orthop Trauma"},{"issue":"02","key":"10.1055\/s-0042-1748783_bib0029","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.injury.2011.06.015","article-title":"Complications following autologous bone graft harvesting from the iliac crest and using the RIA: a systematic review","volume":"42","author":"Dimitriou","year":"2011","journal-title":"Injury"},{"issue":"03","key":"10.1055\/s-0042-1748783_bib0030","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1097\/PRS.0b013e3182402d9a","article-title":"What is the price to pay for a free fibula flap? A systematic review of donor-site morbidity following free fibula flap surgery","volume":"129","author":"Ling","year":"2012","journal-title":"Plast Reconstr Surg"},{"issue":"02","key":"10.1055\/s-0042-1748783_bib0031","doi-asserted-by":"crossref","first-page":"204","DOI":"10.2106\/00004623-199602000-00006","article-title":"Donor-site morbidity with use of vascularized autogenous fibular grafts","volume":"78","author":"Vail","year":"1996","journal-title":"J Bone Joint Surg Am"},{"issue":"05","key":"10.1055\/s-0042-1748783_bib0032","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1097\/00000637-199705000-00005","article-title":"Leg morbidity and function following fibular free flap harvest","volume":"38","author":"Shpitzer","year":"1997","journal-title":"Ann Plast Surg"},{"key":"10.1055\/s-0042-1748783_bib0033","doi-asserted-by":"crossref","DOI":"10.1007\/s00402-021-03962-5","article-title":"Vascularized fibular grafts for the treatment of long bone defects: pros and cons. A systematic review and meta-analysis","author":"Feltri","year":"2021","journal-title":"Arch Orthop Trauma Surg"},{"issue":"11","key":"10.1055\/s-0042-1748783_bib0034","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1007\/s00402-020-03354-1","article-title":"Free vascularised medial femoral condyle periosteal flaps in recalcitrant long bone non-union: a systematic review","volume":"140","author":"Weir","year":"2020","journal-title":"Arch Orthop Trauma Surg"},{"issue":"01","key":"10.1055\/s-0042-1748783_bib0035","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1186\/s12891-016-1312-4","article-title":"Autologous bone graft in the treatment of post-traumatic bone defects: a systematic review and meta-analysis","volume":"17","author":"Azi","year":"2016","journal-title":"BMC Musculoskelet Disord"}],"container-title":["Journal of Hand and Microsurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0974322724001571?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0974322724001571?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0042-1748783.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T06:12:31Z","timestamp":1760854351000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0974322724001571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023]]}},"alternative-id":["S0974322724001571"],"URL":"https:\/\/doi.org\/10.1055\/s-0042-1748783","relation":{},"ISSN":["0974-3227"],"issn-type":[{"value":"0974-3227","type":"print"}],"subject":[],"published":{"date-parts":[[2023]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multifactorial Analysis of Treatment of Long-Bone Nonunion with Vascularized and Nonvascularized Bone Grafts","name":"articletitle","label":"Article Title"},{"value":"Journal of Hand and Microsurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1055\/s-0042-1748783","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 THE AUTHORS. Published by ELSEVIER B.V. on behalf of Society for Indian Hand Surgery and Micro Surgeons.","name":"copyright","label":"Copyright"}]}}