{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T19:42:33Z","timestamp":1764099753059,"version":"3.46.0"},"reference-count":37,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Comp Orthop Traumatol"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Objective\u2003The aim of this study was to evaluate the influence of near-cortical over-drilling holes on the mechanical behaviour of locking plate constructs applied in maned wolf's femur by using mechanical testing and finite element method (FEM).<\/jats:p>\n                  <jats:p>Study Design\u2003Seven pairs of adult maned wolves (Chrysocyon brachyurus) femur bones were randomly distributed into four groups. In all groups, a 3.5\u2009mm locking compression plate, designed with 12 combi-holes and one locked, was applied to the lateral surface of the femur. G1 (n\u2009=\u20094) received bicortical locking screws placed in holes 1, 3, 5, 8, 10 and 12. In G2 (n\u2009=\u20095), the plate was applied as used in G1, but the application of the locked screws involved the near-cortical over-drilling technique. In G3 (n\u2009=\u20094), the plate was applied as used in G2, but the size of the near-cortical over-drilling was larger. The combi-holes 6 and 7 were maintained over a 10\u2009mm fracture gap without screws. All constructs were tested for failure in the axial load. The axial load was applied eccentrically to the femoral head.<\/jats:p>\n                  <jats:p>Results\u2003Statistical differences were observed in the maximum load with G3\u2009&gt;\u2009G1 and G3\u2009&gt;\u2009G2, and in the deflection with G2\u2009&gt;\u2009G1 and G2\u2009&gt;\u2009G3. The FEM showed the lowest total displacement of the bone-plate constructs as well as of the plate in G1 compared with G2 and G3.<\/jats:p>\n                  <jats:p>Conclusion\u2003The near-cortical over-drilling technique used in unstable fractures induced in the maned wolf's femur showed by static axial compression test that maximum load and deflection are dependent on drill hole size induced in the near-cortex. Based on FEM, the lowest total displacement of the bone-plate constructs was observed in Group 1.<\/jats:p>","DOI":"10.1055\/s-0042-1748859","type":"journal-article","created":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T19:22:18Z","timestamp":1653420138000},"page":"246-254","source":"Crossref","is-referenced-by-count":0,"title":["Influence of the Near-Cortical Over-Drilling Technique on the Mechanical Behaviour of Locking Plate Constructs Applied in Maned Wolf's Femur"],"prefix":"10.1055","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4683-0478","authenticated-orcid":false,"given":"Rafael C.","family":"Siqueira","sequence":"additional","affiliation":[{"name":"Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, S\u00e3o Paulo State University (UNESP), Rubi\u00e3o J\u00fanior s\/n, Botucatu, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheila C.","family":"Rahal","sequence":"additional","affiliation":[{"name":"Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, S\u00e3o Paulo State University (UNESP), Rubi\u00e3o J\u00fanior s\/n, Botucatu, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciana R.","family":"Mesquita","sequence":"additional","affiliation":[{"name":"Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, S\u00e3o Paulo State University (UNESP), Rubi\u00e3o J\u00fanior s\/n, Botucatu, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiana A.","family":"Voorwald","sequence":"additional","affiliation":[{"name":"Department of Veterinary Surgery, Federal University of Vi\u00e7osa, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin F.","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Department of Materials and Technology, S\u00e3o Paulo State University (UNESP), Guaratinguet\u00e1, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos","family":"Tosati","sequence":"additional","affiliation":[{"name":"Solution Engineering Manager at SAMT - Structural Solutions for Finite Elements, Bauru, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celso R.","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Mechanical and Metallography Testing Laboratory \u2013 LEMM, Ja\u00fa, S\u00e3o Paulo, Rua Luiz Pengo 150, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2861-910X","authenticated-orcid":false,"given":"Paulo S.","family":"Scorsato","sequence":"additional","affiliation":[{"name":"Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, University of Mar\u00edlia (UNIMAR), Mar\u00edlia, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,5,24]]},"reference":[{"issue":"S 02","key":"ref1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.2106\/JBJS.J.00780","article-title":"Effects of construct stiffness on healing of fractures stabilized with locking plates","volume":"92","author":"M Bottlang","year":"2010","journal-title":"J Bone Joint Surg Am"},{"issue":"S 01","key":"ref2","doi-asserted-by":"crossref","first-page":"S35","DOI":"10.1097\/BOT.0b013e3182070f2d","article-title":"Effects of near cortical slotted holes in locking plate constructs","volume":"25","author":"R M Sellei","year":"2011","journal-title":"J Orthop Trauma"},{"key":"ref3","first-page":"91","article-title":"Current concepts to reduce mechanical stiffness in locked plating systems: a review article","volume":"6","author":"N Nanavati","year":"2014","journal-title":"Orthop Res Rev"},{"issue":"S 12","key":"ref4","doi-asserted-by":"crossref","first-page":"S28","DOI":"10.1097\/BOT.0000000000000467","article-title":"Biomechanical concepts for fracture fixation","volume":"29","author":"M Bottlang","year":"2015","journal-title":"J Orthop Trauma"},{"issue":"S 01","key":"ref5","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1016\/S0020-1383(18)30294-8","article-title":"Evolution of fracture treatment with bone plates","volume":"49","author":"P Augat","year":"2018","journal-title":"Injury"},{"issue":"S 01","key":"ref6","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1097\/BOT.0b013e318207885b","article-title":"Biomechanics of far cortical locking","volume":"25","author":"M Bottlang","year":"2011","journal-title":"J Orthop Trauma"},{"issue":"S 01","key":"ref7","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1097\/BOT.0b013e31820711d3","article-title":"Flexible fixation and fracture healing: do locked plating 'internal fixators' resemble external fixators?","volume":"25","author":"H Schmal","year":"2011","journal-title":"J Orthop Trauma"},{"issue":"07","key":"ref8","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1007\/s11999-016-4885-1","article-title":"From bench to bedside: how stiff is too stiff? Far-cortical locking or dynamic locked plating may obviate the question","volume":"474","author":"B K Potter","year":"2016","journal-title":"Clin Orthop Relat Res"},{"issue":"08","key":"ref9","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.2106\/JBJS.H.01038","article-title":"Far cortical locking can reduce stiffness of locked plating constructs while retaining construct strength","volume":"91","author":"M Bottlang","year":"2009","journal-title":"J Bone Joint Surg Am"},{"issue":"07","key":"ref10","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.2106\/JBJS.I.01111","article-title":"Far cortical locking can improve healing of fractures stabilized with locking plates","volume":"92","author":"M Bottlang","year":"2010","journal-title":"J Bone Joint Surg Am"},{"issue":"S 01","key":"ref11","doi-asserted-by":"crossref","first-page":"S29","DOI":"10.1097\/BOT.0b013e3182070cda","article-title":"Far cortical locking enables flexible fixation with periarticular locking plates","volume":"25","author":"J Doornink","year":"2011","journal-title":"J Orthop Trauma"},{"issue":"04","key":"ref12","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/s00423-010-0636-z","article-title":"The dynamic locking screw (DLS) can increase interfragmentary motion on the near cortex of locked plating constructs by reducing the axial stiffness","volume":"395","author":"S D\u00f6bele","year":"2010","journal-title":"Langenbecks Arch Surg"},{"issue":"10","key":"ref13","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1016\/j.injury.2012.10.022","article-title":"The dynamisation of locking plate osteosynthesis by means of dynamic locking screws (DLS)-an experimental study in sheep","volume":"44","author":"M Plecko","year":"2013","journal-title":"Injury"},{"issue":"04","key":"ref14","doi-asserted-by":"crossref","first-page":"e91933","DOI":"10.1371\/journal.pone.0091933","article-title":"DLS 5.0\u2013the biomechanical effects of dynamic locking screws","volume":"9","author":"S D\u00f6bele","year":"2014","journal-title":"PLoS One"},{"issue":"01","key":"ref15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1754-9493-8-3","article-title":"Controlled dynamic stability as the next step in \u201cbiologic plate osteosynthesis\u201d - 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A review of biomechanical principles and in vitro testing","author":"A H Biedrzycki","year":"2019"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"S17","DOI":"10.1016\/j.otsr.2010.03.008","article-title":"The concept of locking plates","volume":"96S","author":"P Cronier","year":"2010","journal-title":"Orthop Traumatol Surg Res"},{"issue":"125","key":"ref35","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/1746-6148-9-125","article-title":"Effect of plate working length on plate stiffness and cyclic fatigue life in a cadaveric femoral fracture gap model stabilized with a 12-hole 2.4\u2009mm locking compression plate","volume":"9","author":"P Chao","year":"2013","journal-title":"BMC Vet Res"},{"issue":"06","key":"ref36","doi-asserted-by":"crossref","first-page":"712","DOI":"10.2460\/ajvr.78.6.712","article-title":"Biomechanical comparison of a 3.5-mm conical coupling plating system and a 3.5-mm locking compression plate applied as plate-rod constructs to an experimentally created fracture gap in femurs of canine cadavers","volume":"78","author":"G Tremolada","year":"2017","journal-title":"Am J Vet Res"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1136\/inp.g7695","article-title":"Advances in internal fixation locking plates","volume":"37","author":"G Arthurs","year":"2015","journal-title":"In Pract"},{"issue":"01","key":"ref38","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.medengphy.2013.09.005","article-title":"Simulation-based particle swarm optimization and mechanical validation of screw position and number for the fixation stability of a femoral locking compression plate","volume":"36","author":"C H Lee","year":"2014","journal-title":"Med Eng Phys"}],"container-title":["Veterinary and Comparative Orthopaedics and Traumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0042-1748859.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T19:39:44Z","timestamp":1764099584000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0042-1748859"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,24]]},"references-count":37,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2022,8,30]]},"published-print":{"date-parts":[[2022,7]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0042-1748859","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0932-0814","2567-6911"],"issn-type":[{"type":"print","value":"0932-0814"},{"type":"electronic","value":"2567-6911"}],"subject":[],"published":{"date-parts":[[2022,5,24]]}}}