{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T09:44:11Z","timestamp":1768729451202,"version":"3.49.0"},"reference-count":49,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objectives\u2003Cardiac support systems are being used increasingly more due to the growing prevalence of heart failure and cardiogenic shock. Reducing cardiac afterload, intracardiac pressure, and flow support are important factors. Extracorporeal membrane oxygenation (ECMO) and intracardiac microaxial pump systems (Impella) as non-permanent MCS (mechanical circulatory support) are being used increasingly.<\/jats:p><jats:p>\n          Methods\u2003We reviewed the recent literature and developed an international European registry for non-permanent MCS.<\/jats:p><jats:p>\n          Results\u2003Life-threatening conditions that are observed preoperatively often include reduced left ventricular function, systemic hypoperfusion, myocardial infarction, acute and chronic heart failure, myocarditis, and valve vitia. Postoperative complications that are commonly observed include severe systemic inflammatory response, ischemia-reperfusion injury, trauma-related disorders, which ultimately may lead to low cardiac output (CO) syndrome and organ dysfunctions, which necessitates a prolonged ICU stay. Choosing the appropriate device for support is critical. The management strategies and complications differ by system. The \u201cheart-team\u201d approach is inevitably needed.<\/jats:p><jats:p>However despite previous efforts to elucidate these topics, it remains largely unclear which patients benefit from certain systems, when is the right time to initiate (MCS), which support system is appropriate, what is the optimal level and type of support, which therapeutic additive and supportive strategies should be considered and ultimately, what are the future prospects and therapeutic developments.<\/jats:p><jats:p>\n          Conclusion\u2003The European cardiac surgical register ImCarS has been established as an IIT with the overall aim to evaluate data received from the daily clinical practice in cardiac surgery. Interested colleagues are cordially invited to join the register.<\/jats:p><jats:p>\n          Clinical registration number:\u2003DRKS00024560.<\/jats:p><jats:p>\n          Positive Ethics Vote:\u2003AZ 246\/20 Faculty of Medicine, Justus-Liebig-University-Gie\u00dfen.<\/jats:p>","DOI":"10.1055\/s-0042-1749686","type":"journal-article","created":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T22:51:22Z","timestamp":1657579882000},"page":"458-466","source":"Crossref","is-referenced-by-count":5,"title":["Rationale and Initiative of the Impella in Cardiac Surgery (ImCarS) Register Platform"],"prefix":"10.1055","volume":"70","author":[{"given":"Bernd","family":"Niemann","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Giessen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Stoppe","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care Medicine, University Hospital W\u00fcrzburg, W\u00fcrzburg, Bavaria, Germany"},{"name":"Abiomed, Abiomed, Danvers, Massachusetts, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Wittenberg","sequence":"additional","affiliation":[{"name":"Coordinating Center for Clinical Trials, Philipps-University of Marburg, Marburg, Hessia, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne","family":"Rohrbach","sequence":"additional","affiliation":[{"name":"Institute of Physiology, Justus-Liebig-University Giessen, Giessen, Hessen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diyar","family":"Saeed","sequence":"additional","affiliation":[{"name":"Department for Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Billion","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Sch\u00fcchtermann Hospital Bad Rothenfelde, Bad Rothenfelde, Niedersachsen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evgenij","family":"Potapov","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Deutsches Herzzentrum Berlin Ringgold Standard Institution, Berlin, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Oezkur","sequence":"additional","affiliation":[{"name":"Department of Cardiac and Vascular Surgery, University of Mainz, Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6452-8678","authenticated-orcid":false,"given":"Payam","family":"Akhyari","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Medical Faculty, Heinrich Heine University, D\u00fcsseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bastian","family":"Schmack","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University of Essen, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Schibilsky","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University of Freiburg, Freiburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9974-8091","authenticated-orcid":false,"given":"Alexander M.","family":"Bernhardt","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Center Hamburg, Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan D.","family":"Schmitto","sequence":"additional","affiliation":[{"name":"Department of Cardiac-, Thoracic-, Transplantation- and Vascular Surgery, Hannover Medical School, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Hagl","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Masiello","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, San Giovanni di Dio e R.A. 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Karatolios","year":"2018","journal-title":"Resuscitation"},{"issue":"01","key":"ref26","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1161\/CIRCHEARTFAILURE.112.967224","article-title":"Percutaneous left-ventricular support with the Impella-2.5-assist device in acute cardiogenic shock: results of the Impella-EUROSHOCK-registry","volume":"6","author":"A Lauten","year":"2013","journal-title":"Circ Heart Fail"},{"issue":"10","key":"ref27","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1161\/CIRCULATIONAHA.118.036614","article-title":"Impella support for acute myocardial infarction complicated by cardiogenic shock","volume":"139","author":"B Schrage","year":"2019","journal-title":"Circulation"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/S0140-6736(08)60958-7","article-title":"Cardiopulmonary resuscitation with assisted extracorporeal life-support versus conventional cardiopulmonary resuscitation in adults with in-hospital cardiac 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Pappalardo","year":"2017","journal-title":"Eur J Heart Fail"},{"issue":"01","key":"ref42","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/MAT.0000000000000767","article-title":"Simultaneous venoarterial extracorporeal membrane oxygenation and percutaneous left ventricular decompression therapy with Impella is associated with improved outcomes in refractory cardiogenic shock","volume":"65","author":"S M Patel","year":"2019","journal-title":"ASAIO J"},{"issue":"12","key":"ref43","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1016\/j.healun.2015.08.018","article-title":"Benefits of a novel percutaneous ventricular assist device for right heart failure: the prospective RECOVER RIGHT study of the Impella RP device","volume":"34","author":"M B Anderson","year":"2015","journal-title":"J Heart Lung Transplant"},{"issue":"03","key":"ref44","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1002\/ehf2.12148","article-title":"Right ventricular temporal assist 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