{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T08:37:00Z","timestamp":1777365420921,"version":"3.51.4"},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003This study aimed to compare the short- and long-term outcomes of saphenous vein grafts (SVGs) and in situ left internal thoracic artery (LITA) grafts to the left circumflex artery (LCX) territory.<\/jats:p><jats:p>\n          Methods\u2003This study included 678 patients who underwent LITA-left anterior descending (LAD)\u2009+\u2009SVG-LCX grafts and 286 patients who underwent right internal thoracic artery (RITA)-LAD\u2009+\u2009in situ LITA-LCX grafts from January 2002 to December 2020. Short-term and long-term clinical outcomes were compared using inverse probability of treatment weighting adjustment to reduce selection bias.<\/jats:p><jats:p>\n          Results\u2003In-hospital mortality was significantly higher for the SVG-LCX group (p\u2009=\u20090.008), whereas deep sternal wound infection was significantly higher in the LITA-LCX group (p\u2009=\u20090.013).<\/jats:p><jats:p>Survival rates at 5 and 10 years were 83.12 and 71.45% in the SVG-LCX group, whereas 75.24 and 65.54% in the LITA-LCX group (log-rank p\u2009=\u20090.114). Rates of freedom from cardiac events at 5 and 10 years were 92.82 and 85.24% in the SVG-LCX group, whereas 94.89 and 89.46% in the LITA-LCX group (log-rank p\u2009=\u20090.179).<\/jats:p><jats:p>Univariate and multivariate logistic regression analysis showed that proximal severe stenosis was significantly protective against graft dysfunction before discharge (odds ratio, 0.43; 95% confidence interval, 0.23\u20130.81).<\/jats:p><jats:p>\n          Conclusion\u2003Deep sternal wound infection was significantly higher for LITA to LCX bypass whereas in-hospital mortality was higher for SVG to LCX. In situ LITA to LCX bypass grafting exhibited similar long-term outcomes with SVG to LCX bypass grafting in adjusted patient cohorts. Proximal severe stenosis of LCX was protective against graft dysfunction.<\/jats:p>","DOI":"10.1055\/s-0042-1750038","type":"journal-article","created":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T22:51:22Z","timestamp":1657579882000},"page":"441-447","source":"Crossref","is-referenced-by-count":1,"title":["Bypass Grafting to Circumflex: Left Internal Thoracic Artery versus Saphenous Vein"],"prefix":"10.1055","volume":"71","author":[{"given":"Gaku","family":"Uchino","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Hyogo Brain and Heart Center, Himeji, Hyogo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirohisa","family":"Murakami","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Hyogo Brain and Heart Center, Himeji, Hyogo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhiko","family":"Mukohara","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Hyogo Brain and Heart Center, Himeji, Hyogo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Hyogo Brain and Heart Center, Himeji, Hyogo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshikatsu","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Hyogo Brain and Heart Center, Himeji, Hyogo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunsuke","family":"Miyahara","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Hyogo Brain and Heart Center, Himeji, Hyogo, 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