{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,31]],"date-time":"2025-08-31T23:11:05Z","timestamp":1756681865531,"version":"3.37.3"},"reference-count":23,"publisher":"Georg Thieme Verlag KG","issue":"S 01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>\n            Introduction\u2003Respiratory conditions are the most common reason for admission of newborns to a neonatal care unit. The index of contractility (ICON) can be used to measure the thoracic fluid content (TFC) in neonates which is a significant parameter in cases presented with transient tachypnea of newborn (TTN).<\/jats:p><jats:p>\n            Objective\u2003The objective was to compare TFC between newborn infants with TTN compared with other causes of respiratory distress (RD). We tested the hypothesis that TFC would be higher in infants with TTN.<\/jats:p><jats:p>\n            Study Design\u2003In total, 105 newborns were enrolled at the delivery room and were categorized into three groups: TTN, other causes of RD, and control, according to physical examination and Chest X-Ray. TFC was measured within the first 6\u2009hours for all infants and at 24 and 48\u2009hours for the first two groups.<\/jats:p><jats:p>\n            Results\u2003Demographic data showed higher male participants and use of antenatal steroid therapy in RD groups. TFC within the first 6\u2009hours was higher in RD groups. However, TFC at 24\u2009hours of \u226424\u2009mL\/kg, and TFC drop rate at 24\u2009hours of &gt;12% are statistically significant discriminators of TTN from non-TTN, with sensitivity and specificity of 97.1 and 47.1%, and 60 and 82.4%, respectively (Fig 1 and 2).<\/jats:p><jats:p>\n            Conclusion\u2003ICON can be used in conjunction with clinical parameters and CXR as a tool for differentiation between TTN and other causes of RD within the first 24\u2009hours of life by using the cutoff value of TFC at 24\u2009hours and TFC drop rate. This will allow earlier and optimum management of different causes of RD.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0042-1750119","type":"journal-article","created":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T09:27:17Z","timestamp":1657531637000},"page":"e109-e113","source":"Crossref","is-referenced-by-count":4,"special_numbering":"S","title":["Thoracic Fluid Content in Neonates Presented with Respiratory Distress as a Predictive Tool for Transient Tachypnea of Newborn"],"prefix":"10.1055","volume":"41","author":[{"given":"Mohamed R.","family":"Bassiouny","sequence":"additional","affiliation":[{"name":"Neonatology Unit, Department of Pediatrics, Faculty of Medicine, Mansoura University, Mansoura, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shimaa E.","family":"Abdelhady","sequence":"additional","affiliation":[{"name":"Neonatology Unit, Mansoura Specialized Hospital, Mansoura, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7047-076X","authenticated-orcid":false,"given":"Ali","family":"Sobh","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Primary Immunodeficiency Unit, Department of Pediatrics, Faculty of Medicine, Mansoura University, Mansoura, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,7,10]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.prrv.2012.02.002","article-title":"Respiratory distress of the term newborn infant","volume":"14","author":"M O Edwards","year":"2013","journal-title":"Paediatr Respir Rev"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"177","DOI":"10.3126\/jnps.v33i3.8447","article-title":"Clinical profile and outcome of neonates admitted to neonatal intensive care unit (NICU) at a tertiary care centre in Eastern Nepal","volume":"33","author":"G S Shah","year":"2013","journal-title":"J Nepal Paediatr"},{"volume-title":"Contemporary Diagnosis and Management of Neonatal Respiratory Diseases. 3rd ed","year":"2003","author":"L E Weisman","key":"ref3"},{"issue":"01","key":"ref4","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.1365-3016.2007.00875.x","article-title":"Severe respiratory disorders in term neonates","volume":"22","author":"J B Gouyon","year":"2008","journal-title":"Paediatr Perinat Epidemiol"},{"issue":"03","key":"ref5","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.prrv.2007.07.001","article-title":"Congenital and neonatal pneumonia","volume":"8","author":"M D Nissen","year":"2007","journal-title":"Paediatr Respir Rev"},{"issue":"04","key":"ref6","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1001\/jama.2010.1015","article-title":"Respiratory morbidity in late preterm births","volume":"304","author":"J U Hibbard","year":"2010","journal-title":"JAMA"},{"issue":"04","key":"ref7","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s12098-016-2288-7","article-title":"Diagnostic performance of point of care ultrasonography in identifying the etiology of respiratory distress in neonates","volume":"84","author":"H Rachuri","year":"2017","journal-title":"Indian J Pediatr"},{"issue":"09","key":"ref8","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1038\/jp.2017.100","article-title":"Thoracic fluid content by electric bioimpedance correlates with respiratory distress in newborns","volume":"37","author":"G Paviotti","year":"2017","journal-title":"J Perinatol"},{"issue":"01","key":"ref9","first-page":"46","article-title":"Electrical cardiometry compared to transesophageal doppler for hemodynamics monitoring and fluid management in pediatrics undergoing Kasai operation. A randomized controlled trial","volume":"6","author":"M Lotfy","year":"2018","journal-title":"Paediatr Anaesth"},{"issue":"03","key":"ref10","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/s10877-019-00330-y","article-title":"Accuracy and precision of non-invasive cardiac output monitoring by electrical cardiometry: a systematic review and meta-analysis","volume":"34","author":"M Sanders","year":"2020","journal-title":"J Clin Monit Comput"},{"issue":"02","key":"ref11","doi-asserted-by":"crossref","first-page":"131","DOI":"10.3126\/jnhrc.v16i2.20297","article-title":"Analysis of neonatal respiratory distress in neonatal intensive care unit at Nepal Medical College","volume":"16","author":"P Rijal","year":"2018","journal-title":"J Nepal Health Res Counc"},{"issue":"10","key":"ref12","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1542\/pir.35.10.417","article-title":"Respiratory distress in the newborn","volume":"35","author":"S Reuter","year":"2014","journal-title":"Pediatr Rev"},{"issue":"08","key":"ref13","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/BF02011835","article-title":"A radiologic update on medical diseases of the newborn chest","volume":"25","author":"R H Cleveland","year":"1995","journal-title":"Pediatr Radiol"},{"issue":"05","key":"ref14","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1177\/000992289703600506","article-title":"The first chest radiograph in neonates exhibiting respiratory distress at birth","volume":"36","author":"S Kurl","year":"1997","journal-title":"Clin Pediatr (Phila)"},{"issue":"02","key":"ref15","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)\u2014a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"P A Harris","year":"2009","journal-title":"J Biomed Inform"},{"issue":"01","key":"ref16","first-page":"65","article-title":"Neonatal respiratory distress in Omdurman Maternity Hospital, Sudan","volume":"14","author":"S M Abdelrahman","year":"2014","journal-title":"Sudan J Paediatr"},{"issue":"10","key":"ref17","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1038\/jp.2011.191","article-title":"Increased risk for respiratory distress among white, male, late preterm and term infants","volume":"32","author":"J S Anadkat","year":"2012","journal-title":"J Perinatol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"24","DOI":"10.3109\/14767058.2010.507971","article-title":"Transient tachypnea of the newborn: what is new?","volume":"23","author":"M Yurdak\u00f6k","year":"2010","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"06","key":"ref19","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/jp.2016.2","article-title":"Hemodynamic reference for neonates of different age and weight: a pilot study with electrical cardiometry","volume":"36","author":"K H Hsu","year":"2016","journal-title":"J Perinatol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"564902","DOI":"10.3389\/fped.2020.564902","article-title":"Thoracic fluid content (TFC) measurement using impedance cardiography predicts outcomes in critically ill children","volume":"8","author":"L Sumbel","year":"2021","journal-title":"Front Pediatr"},{"issue":"03","key":"ref21","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1002\/ppul.24635","article-title":"Using lung ultrasound to quantitatively evaluate pulmonary water content","volume":"55","author":"H F Zong","year":"2020","journal-title":"Pediatr Pulmonol"},{"key":"ref22","first-page":"1","article-title":"Lung ultrasound to quantitatively evaluate extravascular lung water content and its clinical significance","volume":"16","author":"G Guo","year":"2020","journal-title":"J Matern Fetal Neonatal 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